anti-Coagulation Factor XIII, A1 Polypeptide (F13A1) Antibodies

F13A1 encodes the coagulation factor XIII A subunit. Additionally we are shipping Coagulation Factor XIII, A1 Polypeptide Kits (49) and Coagulation Factor XIII, A1 Polypeptide Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
F13A1 60327 O08619
F13A1 2162 P00488
F13A1 74145 Q8BH61
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Top anti-Coagulation Factor XIII, A1 Polypeptide Antibodies at antibodies-online.com

Showing 10 out of 300 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238563 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A:H1299 7.5 % SDS PAGE antibody diluted at 1:1000 IHC-P Image Factor XIIIa antibody [N1N3] detects Factor XIIIa protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. Factor XIIIa antibody [N1N3] , diluted at 1:500. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated WB Western blot analysis of Factor XIII A expression in HeLa (A), A549 (B), rat heart (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human A549 cell lysate; Primary Ab: 3µg/ml Rabbit Anti-Mouse F13A1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
$342.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Human A549 Cells. 100 μg Log in to see 13 to 16 Days
$332.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Rat Serum. 100 μg Log in to see 13 to 16 Days
$362.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$522.50
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Human Placenta (formalin-fixed, paraffin-embedded) stained with F13A1 antibody ABIN462397 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Anti-F13A1 / Factor XIIIa antibody IHC staining of human skin, dermal inflammatory cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN462397 concentration 3 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details

Top referenced anti-Coagulation Factor XIII, A1 Polypeptide Antibodies

  1. Human Polyclonal F13A1 Primary Antibody for ELISA, WB - ABIN548008 : Higaki, Nakano, Onaka, Amano, Tanioka, Harada, Hashimoto, Sakaida, Okita: Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease. in Journal of gastroenterology and hepatology 2006 (PubMed)

  2. Human Monoclonal F13A1 Primary Antibody for ELISA, FACS - ABIN5577653 : Davie, Fujikawa, Kisiel: The coagulation cascade: initiation, maintenance, and regulation. in Biochemistry 1991 (PubMed)

More Antibodies against Coagulation Factor XIII, A1 Polypeptide Interaction Partners

Cow (Bovine) Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. kinetic and structural analysis of interactions between thrombin and the Factor XIII activation peptide

Human Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. this study characterized a novel mutation in AP-FXIII representing only the fourth case of the rare FXIII-A type II deficiency

  2. Overall, genetically-determined FXIIIA levels have a significant long-term prognostic role, suggesting that a pharmacogenetics approach might help to select those AMI patients at risk of poor prognosis in the need of dedicated treatments.

  3. Inflammatory monocytes highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for lung squamous carcinomas cell invasion and metastases.

  4. Effect of factor XIII levels and polymorphisms on the risk of myocardial infarction in young patients

  5. Polymorphisms of F2, PROC, PROZ, and F13A1 Genes are Associated With Recurrent Spontaneous Abortion in Chinese Han Women.

  6. Coagulation factor FXIII-A (FXIIIA) was found to express specifically in the fetal beta islets but not in the alpha/delta islets.

  7. Factor XIIIa (AC-1A1) is a sensitive and specific nuclear marker for sebaceous differentiation...which can be utilized to aid in the diagnosis of sebaceous neoplasms.

  8. Our meta-analysis supports an association between F13A1 Val34Leu and recurrent pregnancy loss.

  9. A brief history of some key events in the conversion of fibrinogen to fibrin has been reviewed. (Review)

  10. The results of this study suggest that these biomarker F13A1 can serve as a potential non-invasive early diagnosis platform reflecting PiB-PET imaging for Mild Cognitive Impairment and Alzheimer's Disease.

  11. F13A1 gene mutations in 73 patients treated with recombinant FXIII-A2

  12. Results show that the missense mutations-causing mild FXIII de fi ciency influence different aspects of FXIII function and can be functionally categorized on the basis of their expression phenotype.

  13. These findings provide insight into assembly of the fibrinogen/FXIII-A2B2 complex in both physiologic and therapeutic situations.

  14. FXIIIa exhibits a preference for Q237 in crosslinking reactions within fibrinogen alphaC (233-425) followed by Q328 and Q366.

  15. factor XIII Val34Leu polymorphism is associated with coronary artery diseases risk, especially myocardial infarction. Age and sex did not affect the relationship between factor XIII Val34Leu polymorphism and diseases risk (Meta-Analysis)

  16. Mounting evidence now suggests that platelet FXIII-A modulates hemostasis by several different mechanisms. This condensed review discusses recent advances in the understanding of the novel intracellular and extracellular functions of platelet FXIII-A. [review]

  17. It is a unique case showing the combination of a highly aggressive angiosarcoma and presence of inherited FXIII deficiency. It is also a rare example demonstrating the benefit of FXIII genotyping besides the expected acquired FXIII deficiency possibly due to neoplasm induced increased consumption by elevated crosslinking of fibrin fibers.

  18. The Val34Leu polymorphism of FXIII was not found in Korean people, and compared with Caucasians, a noticeably low incidence of deep vein thrombosis was shown.

  19. Genetic basis of severe factor XIII deficiency in a large cohort of Indian patients has been uncovered.

  20. Our meta-analysis suggests that there is no evidence for strong association between FXIII Val34Leu polymorphisms and intracerebral hemorrhage--{review}

Mouse (Murine) Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. Factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.

  2. Suggest that resident macrophages maintain plasma FXIII-A and exclude the platelet lineage as a major contributor.

  3. These findings provide insight into assembly of the fibrinogen/FXIII-A2B2 complex in both physiologic and therapeutic situations.

  4. Mast cells have the ability to produce and degrade FXIIIA depending on their chymase expression profile: mast cells expressing chymase degrade FXIIIA, whereas mast cells that do not express chymase mainly produce FXIIIA

  5. A lack of factor XIII leads to prolonged clotting times, increased signs of inflammation, and elevated bacterial dissemination in streptococcal skin diseases.

  6. FXIII is a significant determinant of mucosal healing and clinical outcome following inflammatory colitis induced mucosal injury

  7. These findings expose a newly recognized, essential role for fibrin crosslinking during whole blood clot formation and consolidation and establish FXIIIa activity as a key determinant of thrombus composition and size.

  8. related to islet dysfunction during the development of type 2 diabetes

  9. 5-HT inhibits Factor XIII-A-mediated plasma fibronectin matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation

  10. High Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion.

  11. Fibrinogen from mice harboring the Fibgamma390-396A mutation exhibited reduced binding to FXIII, and plasma from these mice exhibited delayed FXIII activation and fibrin crosslinking, indicating these residues mediate FXIII binding and activation.

  12. FXIII-A serves as a preadipocyte-bound proliferation/differentiation switch that mediates effects of hepatocyte-produced circulating pFN.

  13. Physiological significance of mouse TG2 and Factor XIII through identification of substrate proteins in MC3T3-E1 cells.

  14. Studies indicate that in FXIII-A-knockout mice, tail-tip bleeding times are doubled and clot stability, assessed by thromboelastography, was impaired compared with wild-type mice.

  15. FXIIIA mRNA was regulated by the MAP kinase pathway.

  16. Data indicate that FXIIIa-targeted probe signals showed good overlap with immune-fluorescent fibrin staining images.

  17. factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics

  18. Inhibition of TG2 and FXIIIA during early development of lesions reduced the macrophage content in the media of atherosclerotic vessels, while not affecting lesion size or geometric remodeling

  19. Knockout mouse studies suggest that plasma FXIII-A does not derive primarily (if at all) from circulating platelets and indeed may not derive from the megakaryocyte lineage.

  20. All FXIII2/2 and FXIII2/+ mice died within 5 days after MI from left ventricular (LV) rupture and had locally reduced levels of FXIII.

Coagulation Factor XIII, A1 Polypeptide (F13A1) Antigen Profile

Protein Summary

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

Gene names and symbols associated with F13A1

  • coagulation factor XIII A1 chain (F13a1) antibody
  • coagulation factor XIII, A1 polypeptide b (f13a1b) antibody
  • coagulation factor XIII A chain (F13A1) antibody
  • coagulation factor XIII, A1 subunit (F13a1) antibody
  • coagulation factor XIII A chain (F13a1) antibody
  • 1200014I03Rik antibody
  • AI462306 antibody
  • F13A antibody
  • F13A1 antibody
  • wu:fo83d04 antibody
  • zgc:153334 antibody

Protein level used designations for F13A1

coagulation factor XIII A chain , coagulation factor XIII, A1 subunit , coagulation factor XIIIa , protein-glutamine gamma-glutamyltransferase A chain , transglutaminase A chain , FX111a-87 , fo83d04 , coagulation factor XIII A1 subunit , coagulation factor XIII, A1 polypeptide , blood coagulation factor XIII A1 subunit , coagulation factor XIIIA , Coagulation factor XIII A chain , FSF, A subunit , TGase , bA525O21.1 (coagulation factor XIII, A1 polypeptide) , coagulation factor XIII, A polypeptide , factor XIIIa , fibrin stabilizing factor, A subunit , fibrinoligase , transglutaminase. plasma , Factor XIIIA , coagulation factor XIII, alpha subunit , coagulation factor XIII A chain-like

GENE ID SPECIES
60327 Rattus norvegicus
561287 Danio rerio
478711 Canis lupus familiaris
462413 Pan troglodytes
100060428 Equus caballus
617881 Bos taurus
395420 Gallus gallus
711264 Macaca mulatta
2162 Homo sapiens
74145 Mus musculus
100020636 Monodelphis domestica
100401849 Callithrix jacchus
100479900 Ailuropoda melanoleuca
100539806 Meleagris gallopavo
100581513 Nomascus leucogenys
100153504 Sus scrofa
100719684 Cavia porcellus
101108612 Ovis aries
101671512 Mustela putorius furo
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