Protein Summary

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CCDC88A

• coiled-coil domain containing 88A (CCDC88A) antibody
• coiled coil domain containing 88A (Ccdc88a) antibody

• A430106J12Rik antibody
• AI848406 antibody
• Ape antibody
• C130096N06Rik antibody
• C330012F17Rik antibody
• Show all synonym aliases
• D130005J21Rik antibody
• DKFZp459N1815 antibody
• Girdin antibody
• Giv antibody
• Grdn antibody
• Hkrp1 antibody
• KIAA1212 antibody
• RGD1306694 antibody

Protein level used designations for CCDC88A

AKT-phosphorylation enhancer , Hook-related protein 1 , g alpha-interacting vesicle-associated protein , girders of actin filament , girders of actin filaments , girdin , Akt-phosphorylation enhancer , coiled-coil domain-containing protein 88A , coiled-coil domain containing 88A , Galpha-interacting vesicle-associated protein