Complement Factor H-Related 1 (CFHR1) ELISA Kits

CFHR1 encodes a secreted protein belonging to the complement factor H protein family. Additionally we are shipping CFHR1 Antibodies (63) and CFHR1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CFHR1 CFHR1 50702  
Anti-Rat CFHR1 CFHR1 289057  
CFHR1 3078 Q03591
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Top CFHR1 ELISA Kits at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 12.5 ng/mL 25-1600 ng/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Details
Human 0.014 ng/mL n/a   96 Tests 11 to 16 Days
$673.75
Details
Human < 0.263 ng/mL 0.625 ng/mL - 40 ng/mL   96 Tests 11 to 18 Days
$966.52
Details

Top referenced CFHR1 ELISA Kits

  1. Human CFHR1 ELISA Kit for Sandwich ELISA - ABIN1450245 : Popek, Kapka-Skrzypczak, Sawicki, Wolińska, Skrzypczak, Czajka: IL‑6 and IL‑8 enhance factor H binding to the cell membranes. in Molecular medicine reports 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human CFHR1 ELISA Kit for Competition ELISA - ABIN831963 : Westwood, Liu, Baird, Anand, Nevado-Holgado, Newby, Pikkarainen, Hallikainen, Kuusisto, Streffer, Novak, Blennow, Andreasson, Zetterberg, Smith, Laakso, Soininen, Lovestone: The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology. in Alzheimer's research & therapy 2018 (PubMed)

More ELISA Kits for CFHR1 Interaction Partners

Human Complement Factor H-Related 1 (CFHR1) interaction partners

  1. These data highlight an unexpected role for FHR1 during sterile inflammation.

  2. FHR-1 acts as a protective factor in human immunity by counteracting factor H-mediated microbial complement evasion

  3. Here, we report the identification of mutations in the CFHR1 gene that generate by gene conversion events and that are undetectable by the current Next-generation massive parallel DNA sequencing (NGS) analysis approaches.

  4. In conclusion, the CFHR3,1D genotype did not associate with progression toward CKD stages 3 and 5 in our white population of patients with IgAN, although it did associate with a reduced level of glomerular immune deposits.

  5. Novel genetic rearrangement generated from a heterozygous deletion spanning 146 Kbp involving multiple CFHR genes leading to a CFHR1-R5 hybrid protein. This deletion was found in four family members presenting with a familial dominant glomerulopathy.

  6. Plasma FHR-1 and the FHR-1/fH ratio were elevated in IgA nephropathy and associated with progressive disease.

  7. A role of FHR-1 in IgA nephropathy pathogenesis is to compete with complement regulation by factor H.

  8. We conclude that the relationship between complement-regulatory proteins CFHR1 and CFHR3 and response to anti-CD20 mAb therapy varies based on the specific anti-CD20 mAb used.

  9. To our knowledge, this is the first evaluation of the involvement of the CFHR3/CFHR1 deletion and age-related macular degeneration in CFH Y402H polymorphism Brazilian patients.

  10. These results identify C-reactive protein as a ligand for FHR-1 and suggest that FHR-1 enhances, rather than inhibits, complement activation, which may explain the protective effect of FHR-1 deficiency in age-related macular degeneration.

  11. The CFHR1 level in plasma of T2DM patients were significantly higher than that of the healthy controls.

  12. CFHL-1 is a CFH gene splice variant.

  13. We investigated whether the causal sequence variant resides in the CFH gene or the neighboring complement factor H-related 1 (CFHR1) gene, and fine mapping Implicates a deletion of CFHR1 in protection from IgA nephropathy in Han Chinese

  14. Next-generation sequencing of the CFH region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR1]

  15. Studies indicate that complement factor H-related proteins (FHR1-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  16. These results suggest that the combination of quantitative and qualitative variations in the complement proteins encoded by CFH, CFHR3 and CFHR1 genes is key for the association of these haplotypes with disease.

  17. Genetic variants in CFH, CFHR3, and CFHR1 affect complement activation and thereby predispose patients to develop IgA nephropathy.

  18. An average of 15.2% of factor H-autoantibody positive individuals with rheumatic diseases or hemolytic uremic syndrome had homozygous deficiency of CFHR1.

  19. Data indicate that the autoantigenic epitope of complement factor H (CFH) and its homologous site in CFH-related protein-1(CFHR1) are structurally different

  20. Prompt use of immunosuppressive agents and plasma exchanges are useful for improving outcomes in pediatric patients with anti-complement factor H-associated HUS.

CFHR1 Antigen Profile

Antigen Summary

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Gene names and symbols associated with CFHR1

  • complement factor H-related 1 (Cfhr1) antibody
  • complement factor H-related protein 1 (LOC735590) antibody
  • complement factor H-related protein 1 (LOC746429) antibody
  • complement factor H related 1 (CFHR1) antibody
  • AI194696 antibody
  • CFHL antibody
  • CFHL1 antibody
  • CFHL1P antibody
  • CFHR1P antibody
  • CFHRB antibody
  • FHR1 antibody
  • H36-1 antibody
  • H36-2 antibody
  • HFL1 antibody
  • HFL2 antibody

Protein level used designations for CFHR1

complement component factor h-like 1 , complement factor H-related protein , complement factor H-related protein 1 , complement factor H-related 1 , FHR-1 , H factor (complement)-like 1 , H factor (complement)-like 2 , H-factor-like 1 , H36 , complement factor H-related 1 pseudogene , h factor-like protein 1

GENE ID SPECIES
50702 Mus musculus
289057 Rattus norvegicus
735590 Pan troglodytes
746429 Pan troglodytes
3078 Homo sapiens
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