Cyclin Y Proteins (CCNY)

Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009].. Additionally we are shipping Cyclin Y Antibodies (58) and Cyclin Y Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCNY 219771 Q8ND76
CCNY 67974 Q8BGU5
Rat CCNY CCNY 361261  
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Top Cyclin Y Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days

CCNY Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)

More Proteins for Cyclin Y (CCNY) Interaction Partners

Fruit Fly (Drosophila melanogaster) Cyclin Y (CCNY) interaction partners

  1. CycY/Eip63E form a cyclin (show PCNA Proteins)/Cdk (show CDK4 Proteins) complex that is essential for several developmental processes.

Human Cyclin Y (CCNY) interaction partners

  1. increased expression of CCNY was significantly associated with cell proliferation and migration.

  2. Amplification of gene CCNY is associated with metastatic lung adenocarcinoma.

  3. findings revealed an unrecognized role of Caprin-2 (show CAPRIN2 Proteins) in facilitating LRP5 (show LRP5 Proteins)/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14 (show CDK14 Proteins), Cyclin Y, and LRP5 (show LRP5 Proteins)/6.

  4. we believe that CCNY has biological effect in breast cancer (BC) development, and its inhibition via an RNA interference lentiviral system may provide a therapeutic option for BC

  5. CCNY was significantly upregulated in ovarian cancer cell lines and tissues. Significant association was observed between CCNY expression and clinicopathological stage and lymph node metastasis. It significantly exacerbated proliferation, migration, and invasion of A2780 cells, in vitro and in nude mice. It significantly increased c-Myc (show MYC Proteins), cyclin D1 (show CCND1 Proteins), PFTK1 (show CDK14 Proteins), ki67 (show MKI67 Proteins), and OGT (show OGT Proteins) protein expressions in xenograft tumor tissues.

  6. Activation of PCTAIRE-1 (show CDK16 Proteins) is mediated through interaction with the phosphorylated form of cyclin Y in complex with 14-3-3 (show YWHAQ Proteins).

  7. Our findings highlight a PFTK1 (show CDK14 Proteins)-CCNY complex in activating noncanonical Wnt (show WNT2 Proteins) signaling in HCC (show FAM126A Proteins) cells.

  8. Human cyclin Y (CCNY) is a phosphoprotein in vivo and phosphorylation of CCNY by CDK14 (show CDK14 Proteins) triggers its ubiquitination and degradation.

  9. Cyclin Y regulates the expression and membrane trafficing of PCTAIRE (show CDK16 Proteins) kinases (PCTK). (Review)

  10. CCNY (show CDK16 Proteins)binding to CDK16 required a region upstream of the kinase domain and was found to be inhibited by phosphorylation of serine 153, a potential PKA phosphorylation site.

Mouse (Murine) Cyclin Y (CCNY) interaction partners

  1. Here we show that Cyclin Y-like 1 (Ccnyl1) and Cyclin Y (Ccny) have overlapping function and are crucial for mouse embryonic development and mammary stem/progenitor cell functions. Double knockout of Ccnys results in embryonic lethality at E16.5

  2. these results provide a new link between CCNY and lipid metabolism in mice.

  3. CDK16 (show CDK16 Proteins) isolated from testis was unphosphorylated, interacted with CCNY, and exhibited kinase activity.

Cyclin Y (CCNY) Protein Profile

Protein Summary

Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009

Gene names and symbols associated with Cyclin Y Proteins (CCNY)

  • cyclin Y (CCNY)
  • Cyclin Y (CycY)
  • cyclin Y (Ccny)
  • cyclin Y like 1 (CCNYL1)
  • 1700025H17Rik protein
  • 3110050L10Rik protein
  • 4631402G10Rik protein
  • 5730405I09Rik protein
  • anon-WO0118547.165 protein
  • C10orf9 protein
  • CBCP1 protein
  • CCNX protein
  • CFP1 protein
  • CG14939 protein
  • Dcyclin Y protein
  • Dmel\\CG14939 protein
  • i182 protein
  • RGD1565969 protein

Protein level used designations for Cyclin Y Proteins (CCNY)

cyclin Y , cyclin-Y-like , CG14939-PA , CG14939-PB , CycY-PA , CycY-PB , drosophila cyclin Y , cyc-Y , cyclin box protein 1 , cyclin fold protein 1 , cyclin-X , cyclin-Y , cyclin-box carrying protein 1

428412 Gallus gallus
450402 Pan troglodytes
698889 Macaca mulatta
100397648 Callithrix jacchus
34593 Drosophila melanogaster
219771 Homo sapiens
613711 Bos taurus
67974 Mus musculus
361261 Rattus norvegicus
100861154 Capra hircus
101122455 Ovis aries
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