anti-Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) Antibodies

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Additionally we are shipping Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHORDC1 26973 Q9UHD1
CHORDC1 315447 D4A4T9
CHORDC1 66917 Q9D1P4
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Top anti-Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CHORDC1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: CHORDC1 Antibody [NBP1-78304] - Antibody was tested in HeLa cells with FITC (green). Nuclei were counterstained with DAPI (blue). Immunohistochemistry: CHORDC1 Antibody [NBP1-78304] - Analysis of CHORDC1 in mouse prostate using DAB with hematoxylin counterstain. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CHORDC1 Antibody [NBP1-85629] - Staining of human stomach, upper shows moderate cytoplasmic and nuclear positivity in glandular cells. Western Blot: CHORDC1 Antibody [NBP1-85629] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CHORDC1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated WB CHORDC1 Antibody (Center) (ABIN1881199) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the CHORDC1 antibody detected the CHORDC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of CHORDC1 in 293 cell lysate with CHORDC1 antibody at (A) 1 and (B) 2 µg/ml. 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ICC, IF, ELISA, WB   100 μg Log in to see 15 to 19 Days
$523.71
Details

Top referenced anti-Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Antibodies

  1. Human Polyclonal CHORDC1 Primary Antibody for WB - ABIN1881199 : Gano, Simon: A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. in Molecular & cellular proteomics : MCP 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CHORDC1 Primary Antibody for ICC, IF - ABIN4298077 : Zhao, Xu, Zhou, Wang, Xie, Ren, Liu, Zhu: MicroRNA-26b inhibits hepatitis B virus transcription and replication by targeting the host factor CHORDC1 protein. in The Journal of biological chemistry 2014 (PubMed)

More Antibodies against Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Interaction Partners

Human Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) interaction partners

  1. NF-kappaB activation in breast cancer cells depends on the presence of the CHORDC1 gene product Morgana.

  2. suppression of miR (show MLXIP Antibodies)-26b expression up-regulates its target gene CHORDC1, which increases HBV enhancer/promoter activities and promotes viral transcription, gene expression, and replication

  3. morgana causes PTEN destabilization, by inhibiting ROCK activity

  4. Chp-1 (show CHP Antibodies) and melusin (show ITGB1BP2 Antibodies) can interact with cochaperones PP5 (show PPP5C Antibodies) and Sgt1 (show SUGT1 Antibodies) and with each other in an ATP-dependent manner

  5. A novel ADP-dependent HSP90 (show HSP90 Antibodies) interaction with the cysteine- and histidine-rich domain (CHORD)-containing protein CHORDC1, is characterized.

  6. This paper described the cloning of a barley CHORD containing protein, but it also described the CHORD containing proteins in other species including human and characterized the CHORD domains.

Mouse (Murine) Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) interaction partners

  1. Morgana silencing blocks metastasis formation in breast cancer mouse models and this phenotype is reverted by IkappaBalpha (show NFKBIA Antibodies) downregulation.

  2. Loss of Morgana expression is associated with drug resistance and chronic myeloid leukemia (show BCL11A Antibodies).

  3. morgana causes PTEN destabilization, by inhibiting ROCK activity

  4. Chp-1 and melusin (show ITGB1BP2 Antibodies) can interact with cochaperones PP5 (show PPP5C Antibodies) and Sgt1 (show SUGT1 Antibodies) and with each other in an ATP-dependent manner

  5. Overexpression of morgana/CHP-1 in NIH3T3 cells leads to the increased stress resistance of the cells.

  6. Morgana/chp-1 downregulation promotes the interaction between ROCK II (show ROCK2 Antibodies) and nucleophosmin (show NPM1 Antibodies), leading to an increased ROCK II (show ROCK2 Antibodies) kinase activity, which results in centrosome amplification.

  7. Full length sequence, gene structure and expression of Chp-1.

  8. The first biochemical evidence demonstrating that mammalian Chp-1 is a novel Hsp90 (show HSP90 Antibodies)-interacting protein.

  9. results suggest that Chordc1 mRNA is under complex and widespread transcriptional regulation during development and implicate Chordc1 in circadian and/or homeostatic mechanisms in mammalian brain.

Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1) Antigen Profile

Protein Summary

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity).

Gene names and symbols associated with CHORDC1

  • cysteine and histidine rich domain containing 1 (CHORDC1) antibody
  • cysteine and histidine rich domain containing 1 (Chordc1) antibody
  • cysteine and histidine-rich domain-containing protein (LOC412067) antibody
  • cysteine and histidine rich domain containing 1 S homeolog (chordc1.S) antibody
  • cysteine and histidine rich domain containing 1 (chordc1) antibody
  • cysteine and histidine-rich domain (CHORD)-containing 1 (Chordc1) antibody
  • cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 (Chordc1) antibody
  • cysteine and histidine-rich domain (CHORD) containing 1b (chordc1b) antibody
  • 1110001O09Rik antibody
  • AA409036 antibody
  • Chp-1 antibody
  • CHP1 antibody
  • MGC89160 antibody
  • morgana antibody
  • NV16801 antibody
  • zgc:63894 antibody

Protein level used designations for CHORDC1

CHORD-containing protein 1 , CHP-1 , chord domain-containing protein 1 , cysteine and histidine-rich domain (CHORD)-containing 1 , cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 , cysteine and histidine-rich domain-containing protein 1 , protein morgana , CHORD domain-containing protein 1 , morgana , cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1 , CHORD containing protein-1

GENE ID SPECIES
26973 Homo sapiens
315447 Rattus norvegicus
412067 Apis mellifera
414542 Xenopus laevis
419009 Gallus gallus
448329 Xenopus (Silurana) tropicalis
466743 Pan troglodytes
476773 Canis lupus familiaris
505144 Bos taurus
694312 Macaca mulatta
100120564 Nasonia vitripennis
100134961 Sus scrofa
100172001 Pongo abelii
66917 Mus musculus
393310 Danio rerio
100726003 Cavia porcellus
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