Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Additionally we are shipping Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 Proteins (10) and many more products for this protein.
Showing 10 out of 63 products:
Human Polyclonal CHORDC1 Primary Antibody for WB - ABIN1881199
Gano, Simon: A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. in Molecular & cellular proteomics : MCP 2010
Show all 3 Pubmed References
Human Polyclonal CHORDC1 Primary Antibody for ICC, IF - ABIN4298077
Zhao, Xu, Zhou, Wang, Xie, Ren, Liu, Zhu: MicroRNA-26b inhibits hepatitis B virus transcription and replication by targeting the host factor CHORDC1 protein. in The Journal of biological chemistry 2014
NF-kappaB activation in breast cancer cells depends on the presence of the CHORDC1 gene product Morgana.
suppression of miR-26b expression up-regulates its target gene CHORDC1, which increases HBV enhancer/promoter activities and promotes viral transcription, gene expression, and replication
morgana causes PTEN destabilization, by inhibiting ROCK activity
Chp-1 and melusin can interact with cochaperones PP5 and Sgt1 and with each other in an ATP-dependent manner
A novel ADP-dependent HSP90 interaction with the cysteine- and histidine-rich domain (CHORD)-containing protein CHORDC1, is characterized.
This paper described the cloning of a barley CHORD containing protein, but it also described the CHORD containing proteins in other species including human and characterized the CHORD domains.
Morgana silencing blocks metastasis formation in breast cancer mouse models and this phenotype is reverted by IkappaBalpha downregulation.
Loss of Morgana expression is associated with drug resistance and chronic myeloid leukemia.
Overexpression of morgana/CHP-1 in NIH3T3 cells leads to the increased stress resistance of the cells.
Morgana/chp-1 downregulation promotes the interaction between ROCK II and nucleophosmin, leading to an increased ROCK II kinase activity, which results in centrosome amplification.
Full length sequence, gene structure and expression of Chp-1.
The first biochemical evidence demonstrating that mammalian Chp-1 is a novel Hsp90-interacting protein.
results suggest that Chordc1 mRNA is under complex and widespread transcriptional regulation during development and implicate Chordc1 in circadian and/or homeostatic mechanisms in mammalian brain.
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity).
CHORD-containing protein 1
, chord domain-containing protein 1
, cysteine and histidine-rich domain (CHORD)-containing 1
, cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
, cysteine and histidine-rich domain-containing protein 1
, protein morgana
, CHORD domain-containing protein 1
, cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1
, CHORD containing protein-1