Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) ELISA Kits

CYP1A2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1A2 Antibodies (185) and CYP1A2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP1A2 1544 P05177
CYP1A2 13077 P00186
CYP1A2 24297 P04799
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Top CYP1A2 ELISA Kits at

Showing 10 out of 21 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Rat 0.118 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
Human 0.264 ng/mL 0.62 ng/mL - 40 ng/mL 96 Tests 13 to 16 Days
Mouse 0.112 ng/mL 0.31 ng/mL - 20 ng/mL   96 Tests 13 to 16 Days
Rabbit 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Guinea Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests 12 to 14 Days
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
Monkey 0.094 ng/mL 0.156-10 ng/mL   96 Tests 12 to 14 Days
Sheep 0.469 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests 11 to 18 Days
  96 Tests 15 to 18 Days

Top referenced CYP1A2 ELISA Kits

  1. Rat (Rattus) CYP1A2 ELISA Kit for Sandwich ELISA - ABIN433558 : Kim, Gallaher, Chen, Yao, Trudo: Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats. in The Journal of nutrition 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human CYP1A2 ELISA Kit for Sandwich ELISA - ABIN418985 : Padmini, Tharani: Differential expression of HO-1 and CYP1A2 during up-regulation of ERK in stressed fish hepatocytes. in Environmental monitoring and assessment 2014 (PubMed)

More ELISA Kits for CYP1A2 Interaction Partners

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. The safety of pomalidomide when administered with CYP1A2 inducers and inhibitors in two studies in healthy volunteers is reported.

  2. The method correctly evaluated the potency of five CYP1A2 inhibitors.

  3. CYP1A2 genetic variants were not associated with treatment resistance when compared to responders to clopidogrel therapy.

  4. The findings of this study do not support the hypothesis of an interaction between the CYP1A2-rs762551 polymorphism and caffeine intake in determining Parkinson disease risk.

  5. CYP1A2 SNPs are significantly associated with the risk for adenomyosis.

  6. The effect of CKD on CYP1A2, CYP2C9, and CYP2C19 was variable and modest compared to CYP2C8 and OATP.

  7. Our findings show that both 2 and 4 caffeine improve 10-km cycling time, but only in those with the AA genotype. Caffeine had no effect in those with the AC genotype and diminished performance at 4 in those with the CC genotype. CYP1A2 genotype should be considered when deciding whether an athlete should use caffeine for enhancing endurance performance.

  8. Review/Meta-analysis: -163C>A polymorphism in intron 1 may play a key role for the inducibility of CYP1A2 activity in the human body, particularly in the presence of an inducer, such as cigarette smoking.

  9. CYP1A2*1F polymorphism is associated with esophageal squamous cell carcinoma risk and the risk is modified in salt tea drinkers in Kashmir population.

  10. In conclusion, acute ingestion of caffeine significantly enhanced resistance exercise performance in resistance-trained men who were homozygous for the A allele, but not for C allele carriers.

  11. The in vitro studies of Pristimerin (PTM) with CYP isoforms indicate that PTM has the potential to cause pharmacokinetic drug interactions with other co-administered drugs metabolized by CYP1A2, 3A4 and 2C9.

  12. Phenotyping of CYP 4501A2 Activity by Total Overnight Salivary Caffeine Assessment (TOSCA) in Patients on Warfarin Treatment

  13. Both CYP1A2 and CYP2B4 activities were affected by their coexpression in a manner consistent with formation of the high-affinity POR-CYP1A2-CYP2B4 complex.

  14. The influence of CYP1A2 genotype in the basal and post-caffeine blood pressure response to caffeine ingestion is modified by physical activity status and caffeine consumption level.

  15. The metabolites are predominantly catalyzed by CYP3A4 (77% approximately 87%), with a moderate contribution from CYP3A5 (5% approximately 15%) and CYP1A2 (3.7% approximately 7.5%).

  16. the genetic variations of the CYP1A2 gene did not affect the ergogenicity or side effects derived from the consumption of a moderate dose of caffeine.

  17. The findings of this study indicate that CYP2C19 contribute to the metabolism of MDMA to MDA in humans

  18. a positive association between caffeine intake and abstract reasoning exists in the CC homozygous of the -163C>A polymorphism of CYP1A2 gene.

  19. CYP1A2 C164A polymorphism has an interaction with maternal caffeine intake that affects infant birth size in a Japanese cohort study

  20. findings provide evidences that miR-320 might inhibit the development of Steroid-induced avascular necrosis of femoral head by targeting CYP1A2.

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. CYP1A1 and CYP1A2 localization into different lipid microdomains is governed by their N-terminal and internal protein regions

  2. Removal of cholesterol (an important constituent of ordered domains) led to the relocation of CYP1A2, CYP2B4 and CPR to the disordered regions.

  3. Oxidation kinetics of toluene in CYP1A2-CYP2B4 mixtures with and without cytochrome p450 reductase (CPR) are consistent with a model in which CYP1A2 has a higher affinity for CPR binding.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. Its mRNA expression is decreased by the high level of MRSA, but the low level of MRSA increased its expression.

  2. results demonstrate that 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside enhances hepatic expression of CYP3A4, CYP2E1 and CYP1A2, and thus exacerbates the hepatotoxicity induced by acetaminophen in mice.

  3. Distribution of parent PCB congeners also varied by genotype with strikingly high levels of PCB 77 in poor-affinity Ahr (d) Cyp1a2(-/-) while Ahr (b) Cyp1a2(+/+) mice effectively sequestered coplanar PCBs in the liver.

  4. our results suggest a more important contribution of CYP1A2 to the in vivo plasma clearance and thus detoxification of 4-Aminobiphenyl

  5. hepatic CYP1A2 plays a critical role in the attenuation of hyperoxic lung injury by decreasing lipid peroxidation and oxidative stress in vivo.

  6. Suggest an important role for CYP1A enzymes in the gender-specific modulation of hyperoxic lung injury.

  7. Aryl hydrocarbon receptor mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1.

  8. Results indicate Cyp1a2 genotype is important in susceptibility to PCB-induced deficits in learning and memory.

  9. Miroestrol and deoxymiroestrol significantly up-regulated CYP2B9 while suppressing CYP1A2 at both transcriptional and enzymatic levels.

  10. A report of uroporphyria development in Cyp1a2-/- mice additionally null for both alleles of the hemochromatosis (Hfe) gene and heterozygous for deletion of the uroporphyrinogen decarboxylase (Urod) gene (genotype: Cyp1a2-/-;Hfe-/-;Urod+/-).

  11. High levels of maternal hepatic CYP1A2 protect against deficits in learning and memory in offspring exposed to a mixture of coplanar and noncoplanar PCBs; high-affinity AHR is the next most important factor in protection of offspring.

  12. In rodents, aristolochic acid demethylation, mediated by CYP1A2, is a primary pathway of aristolochic acid detoxication.

  13. The expression of Cyp1a1, Cyp1a2, and OGG1genes was significantly up-regulated in mice given diets containing 375 ppm dicyclanil or more.

  14. the TRE element in E1 is essential for constitutive expression of the mouse Cypla2 gene

  15. Liver-specific CYP1A2 plays an important role in persistent induction of CYP1A1 in liver, but not lung.

  16. CYP1A2 is not required for TCDD-induced immunosuppression in the mouse.

  17. Cyp1a2 is regulated by histone deacetylase inhibitors in mouse hepatocytes.

  18. A link not only between CYP1A2, iron metabolism, and the induction of uroporphyria by polychlorinated biphenyls, but also with subsequent hepatocarcinogenesis.

  19. We speculate that such mitochondrial CYPs may be involved in the generation, or mitigation, of the well-known TCDD-inducible oxidative stress response.

  20. maternal hepatic CYP1A2, by sequestering dioxin and thus altering the pharmacokinetics, protects the embryos from toxicity and birth defects

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. In the present study, CYP1A2 expression in liver increased in groups exposed to single exposures of 5 mgkg-bw- 1 (p = 0.044) and 20 mgkg-bw- 1 (p = 0.033) relative to controls

  2. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 in pigs.

  3. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A2 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  4. Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2

  5. Effect of beta-napthoflavone on AHR-related gene, CYP1A2, in the pig is reported.

CYP1A2 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Gene names and symbols associated with CYP1A2

  • cytochrome P450 family 1 subfamily A member 2 (CYP1A2) antibody
  • cytochrome P450 1A2 (CYP1A2) antibody
  • cytochrome P450 LM4 (LOC100328937) antibody
  • cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2) antibody
  • cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2) antibody
  • cytochrome P450 1A2 (VDBG_06455) antibody
  • cytochrome P450 1A2-like (LOC101825565) antibody
  • cytochrome P450 1A2 (LOC102130662) antibody
  • CP12 antibody
  • CP450 antibody
  • CYP-IA2 antibody
  • Cyp1a1 antibody
  • CYP1A2 antibody
  • CYP1A5 antibody
  • CYPD45 antibody
  • CYPIA2 antibody
  • P-450d antibody
  • P3-450 antibody
  • P450(PA) antibody
  • P450-3 antibody
  • P450-PM4 antibody
  • RATCYPD45 antibody

Protein level used designations for CYP1A2

CYPIA2 , P450 form 4 , aryl hydrocarbon hydroxylase , cytochrome P(3)450 , cytochrome P450 1A2 , cytochrome P450 4 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 , cytochrome P450-P3 , dioxin-inducible P3-450 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , P450 LM4 , P450 isozyme 4 , cytochrome P450 isozyme 4 , cytochrome P450-PM4 , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 1 , cytochrome P450, 1a2, aromatic compound inducible , cytochrome P450-P2 , Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d) , P-448 , P450-D , cytochrome P-448 , cytochrome P-450d , cytochrome P450, 1a2 , cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d) , cytochrome P450-D , CYPIA5 , cytochrome P450 1A5 , cytochrome P450 TCDDAA , Cytochrome P450-MC4 , Hepatic cytochrome P-450MC1 , cytochrome P-450 form 4 , cytochrome P-450IA2 , pulmonary cytochrome P-450MC1 , Cholesterol 25-hydroxylase , cholesterol 25-hydroxylase , cytochrome P-450 , cytochrome P450, family 1, subfamily A, polypeptide 2

1544 Homo sapiens
554345 Felis catus
100328937 Oryctolagus cuniculus
100172368 Pongo abelii
13077 Mus musculus
24297 Rattus norvegicus
494010 Canis lupus familiaris
9536166 Verticillium alfalfae VaMs.102
100135513 Cavia porcellus
100152910 Sus scrofa
396051 Gallus gallus
101825565 Mesocricetus auratus
100392712 Callithrix jacchus
102130662 Macaca fascicularis
503552 Bos taurus
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