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CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Antibodies (81) and CYP2B6 Proteins (5) and many more products for this protein.
Showing 5 out of 15 products:
Mouse (Murine) CYP2B6 ELISA Kit for Sandwich ELISA - ABIN426458
Cao, Hua, Wang, Chen: Exposure of pregnant mice to triclosan impairs placental development and nutrient transport. in Scientific reports 2017
Case Reports: CYP2B6-deficient alleles may be responsible for an increased conversion of ifosfamide into neurotoxic metabolites, leading to encephalopathy.
The concentration-time curve (AUC(0(R)96)), maximum plasma concentration (Cmax), and terminal half-life (t1/2) values of Bupropion in CYP2B6*1/*4 were lower than those of CYP2B6*1/*1. The hydroxybupropion (HBUP) Cmax values in CYP2B6*4/*6 and CYP2B6*1/*4 increased by 1.12-fold and 1.97-fold, whereas the HBUP Cmax value in CYP2B6*1/*6 decreased to a value 1.64-fold lower than that in CYP2B6*1/*1
CYP2B6-efavirenz analog complex provides a useful platform to investigate computationally as well as biophysically the effect of genetic polymorphisms on binding of the widely studied efavirenz.
results indicate that the amino acid substitutions in the CYP2B6 variants suppressed the metabolic activation of CPS. CYP2B6 variants have altered capacity to bioactivate CPF (show NR5A2 ELISA Kits) and may affect individual susceptibility of CPF (show NR5A2 ELISA Kits)
The findings of this study indicate that CYP2B6 contribute to the metabolism of MDMA to MDA in humans
The first data of several CYP2B6 polymorphisms in Roma population.
With consensus recommendations on downregulation, CYP2C (show CYP2C19 ELISA Kits) induction, and CYP2B6 positive control.
Genotyping of CYP2B6 may therefore be of value when assessing dose requirements in methadone maintenance treatment.
Genomic variation in CYP2B6 may explain, at least in part, severity of Neonatal Abstinence Syndrome
CYP2B6 haplotype predicts efavirenz plasma concentration in black South African HIV-1-Infected children.
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
cytochrome P450 2B6
, cytochrome P450 CYP2B30
, cytochrome P450, family 2, subfamily B, polypeptide 6
, cytochrome P450 PBD-2
, cytochrome P450, family 2, subfamily B, polypeptide 11
, cytochrome P450 2B3
, cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
, cytochrome P450IIB3
, 1,4-cineole 2-exo-monooxygenase
, cytochrome P450 IIB1