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CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Kits (20) and CYP2C19 Proteins (3) and many more products for this protein.
Showing 10 out of 33 products:
Cow (Bovine) Polyclonal CYP2C19 Primary Antibody for WB - ABIN2777003
Ji, Olson, Zhang, Hildebrandt, Wang, Ingle, Fredericksen, Sellers, Miller, Dixon, Brauch, Eichelbaum, Justenhoven, Hamann, Ko, Brüning, Chang-Claude, Wang-Gohrke, Schaid, Weinshilboum: Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. in Cancer research 2008
Nerolidol induces endoplasmic reticulum stress and apoptosis in Human HepG2 Cells through extensive CYP2C19 and CYP1A2 (show CYP1A2 Antibodies) mediated drug oxidation.
Our results suggest that CYP2C19 LOF alleles (*2 and *3) significantly impact the prognosis of patients on clopidogrel therapy after CAS (show CSE1L Antibodies) and that the CYP2C19*2 and CYP2C19*3 alleles have the same effects on prognosis
Behcet's disease patients had lower CYP2C19 enzyme activity and lower frequency of the CYP2C19*17 allele as compared to those of the healthy controls.
CYP2C19 polymorphism does not affect rosuvastatin pharmacokinetics in healthy Taiwanese in a clinically meaningful way.
On-treatment platelet reactivity was compared between patients stratified by diabetes mellitus (DM), CYP2C19*2 status and clopidogrel dose. Both DM and CYP2C19*2 were independently associated with elevated on-treatment platelet reactivity with clopidogrel 75 mg daily.
REVIEW: CYP2C19 and CYP2D6 (show CYP2D6 Antibodies) genotypes in Pacific peoples
PON1 (show PON1 Antibodies) and CYP2C19 polymorphisms were associated with lower clopidogrel responsiveness in this sample. Despite differences in CYP2C19 polymorphisms across white and non-white patients, genetic admixture by itself was not able to identify clopidogrel hyporesponsiveness.
The study showed that the CYP1A2 (show CYP1A2 Antibodies) (-163C>A) Rs762551 C/C genotype was associated with an increased risk of age-related macular degeneration.
Genetic testing of CYP2C19 may help in prescribing a dose according to genetic makeup and represent the initial steps towards the development of diagnostic tests and therapeutic strategies that will substantially improve human health.
rs4244285 of CYP2C19 have the main effects on coronary heart disease risk.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
cytochrome P450 2C
, (R)-limonene 6-monooxygenase
, (S)-limonene 6-monooxygenase
, (S)-limonene 7-monooxygenase
, S-mephenytoin 4-hydroxylase
, cytochrome P-450 II C
, cytochrome P450 2C19
, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19
, cytochrome P450-11A
, cytochrome P450-254C
, flavoprotein-linked monooxygenase
, mephenytoin 4'-hydroxylase
, mephenytoin 4-hydroxylase
, microsomal monooxygenase
, xenobiotic monooxygenase