Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) ELISA Kits

CYP2J2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2J2 Antibodies (93) and CYP2J2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP2J2 1573 P51589
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More ELISA Kits for CYP2J2 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) interaction partners

  1. Our findings demonstrate that CYP2J2 improves cardiac function by increasing the concentration of circulating EETs, and boosting angiogenesis via the Jagged1/Notch1 signaling pathway in MI-induced heart failure.

  2. A functionally relevant polymorphism of the CYP2J2 gene was independently associated with an increased risk of CAD.

  3. There were 15 genetic variants identified in CYP2J2 genes in three Chinese populations: Han, Tibetan and Uighur.

  4. CYP2J2 50 G>T polymorphism is associated with increased risk of cerebral small vessel disease in Han Chinese.

  5. Single Nucleotide Polymorphism in CYP2J2, which synthesize epoxyeicosatrienoic acids, may modify Cardiovascular outcomes in Renal Transplant recipients.

  6. Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression.

  7. Cell survival decreases with ROS exposure when CYP2J2 is chemically inhibited.

  8. In the villous trophoblast, CYP2C8 was the most abundant protein. Its expression is higher than the CYP2C9 and CYP2J2 in the cytotrophoblast in the embryonic stage of development and remains higher in syncytiotrophoblast of term placenta.

  9. Data show the importance of the formation of a hydrogen bond between cytochrome P450 2J2 arginine 117 (R117) and the keto group of the substrates.

  10. these data can aid the design of other analogues that have reduced cardiotoxicity, which do not modulate CYP2J2's arachidonic acid metabolism.

  11. demonstrate that doxorubicin (DOX) and 7-de-aDOX inhibit CYP2J2-mediated AA metabolism and 7-de-aDOX binds close to the active site to alter the ratio of cardioprotective epoxyeicosatrienoic acids.

  12. The use of LKY-047 as a selective CYP2J2 inhibitor.

  13. Angiotensin II receptor blockers exhibit different degrees of inhibition of the metabolism of arachidonic acid by recombinant CYP2C9, CYP2J2 and liver microsomes.

  14. a computational investigation of the binding of arachidonic acid (AA) to CYP2J2 using homology modelling, induced fit docking (IFD) and molecular dynamics (MD) simulations.

  15. Study found a significant interaction between CYP2J2- rs890293 and PPAR -gamma- rs1805192 and participants with GT or TT of rs890293 and CG or GG of rs1805192 genotype have the highest late-onset Alzheimer's disease risk, compared to participants with GG of rs890293 and CC of rs1805192 genotype.

  16. dysregulation of the CYP epoxyeicosanoid pathway is a key pathological consequence of NASH

  17. CYP2J2 is widely expressed in tissues, especially heart, vascular smooth muscle, salivary glands and placenta. Recent studies have shown that overexpression of CYP2J2 in vivo reverses several pathological processes in animals, including hypertension and other cardiovascular pathologies and insulin resistance.

  18. Homocysteine (Hcy) facilitated cytochrome P-450 CYP2J2 (CYP2J2) upregulation in hepatocellular carcinoma (HCC) cells by DNA demethylation.

  19. Endothelial overexpression of CYP2J2 significantly changed oxylipin profiles.

  20. MAPK signaling pathway was involved in the up-regulation of CYP2J2 levels by glutamate in U251 cells.

Cow (Bovine) Cytochrome P450, Family 2, Subfamily J, Polypeptide 2 (CYP2J2) interaction partners

  1. CYP2J2 should be considered a prime candidate for understanding both genetic and physiological factors affecting serum 25OHD concentrations in cattle and, therefore, vitamin D status.

CYP2J2 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.

Gene names and symbols associated with CYP2J2

  • cytochrome P450 family 2 subfamily J member 2 (CYP2J2) antibody
  • cytochrome P450, family 2, subfamily J, polypeptide 20 (CYP2J20) antibody
  • cytochrome P450 family 2 subfamily J member 2 L homeolog (cyp2j2.L) antibody
  • cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2) antibody
  • CPJ2 antibody
  • CYP2J2 antibody

Protein level used designations for CYP2J2

CYPIIJ2 , arachidonic acid epoxygenase , cytochrome P450 2J2 , cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2 , flavoprotein-linked monooxygenase , microsomal monooxygenase , cytochrome P450, family 2, subfamily J, polypeptide 2 , LOW QUALITY PROTEIN: cytochrome P450 2J2

1573 Homo sapiens
424678 Gallus gallus
100158388 Xenopus laevis
510406 Bos taurus
610195 Canis lupus familiaris
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