Protein Summary

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Gene names and symbols associated with DAND5

• DAN domain BMP antagonist family member 5 (DAND5) antibody
• DAN domain family member 5, BMP antagonist S homeolog (dand5.S) antibody
• DAN domain family member 5, BMP antagonist (Dand5) antibody

• 51-B6 antibody
• cer2 antibody
• Cerl-2 antibody
• cerl2 antibody
• Cerr2 antibody
• Show all synonym aliases
• cktsf1b3 antibody
• coco antibody
• crl2 antibody
• dante antibody
• Dte antibody
• grem3 antibody
• SP1 antibody
• xCoco antibody

Protein level used designations for DAND5

DAN domain family member 5 , DAN domain family, member 5 , cerberus 2 , cerberus-like 2 , cerberus-like protein 2 , cerl-2 , cysteine knot superfamily 1, BMP antagonist 3 , gremlin-3 , cerberus-like 2 protein , dante