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The protein encoded by DDX43 is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression.. Additionally we are shipping and DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 43 Proteins (2) and many more products for this protein.
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Human Polyclonal DDX43 Primary Antibody for ICC, IF - ABIN4304647
Abdel-Fatah, McArdle, Johnson, Moseley, Ball, Pockley, Ellis, Rees, Chan: HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer. in British journal of cancer 2014
results demonstrate that DDX43 is a dual helicase and the KH domain is required for its full unwinding activity.
HAGE expression is a potential prognostic marker and a predictor of response to anthracycline treatment in triple negative breast cancer.
DDX43 induces RAS protein expression and signaling, mediating a novel mechanism of MEK inhibitor resistance.
Suggest that the helicase HAGE has a key role in the resistance of ABCB5+ malignant melanoma stem cells to IFNalpha treatment by promoting SOCS1 expression.
DDX43 gene is activated by promoter hypomethylation and DDX43 hypomethylation may be a favorable prognostic factor in acute myeloid leukemia.
data suggest that hypomethylation of the DDX43 promoter may be an early and frequent molecular event in the development of CML in Chinese patients
HAGE cDNA expression is relevant to specific subtypes of acute myeloid leukemiaand to the progression of chronic myeloid leukemia.
DDX43 promoter in frequently hypomethylated in myelodysplastic syndrome and is associated with favourable outcome.
the helicase HAGE is required for ABCB5+ MMIC-dependent tumor growth through promoting RAS protein expression
HAGE protein expression was confirmed in 75% (12/16) of carcinomas as compared to normal tissues
HAGE is a cancer/testis antigen with potential for melanoma immunotherapy
The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression.
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
, probable ATP-dependent RNA helicase DDX43
, DEAD box polypeptide 43
, probable ATP-dependent RNA helicase DDX43-like
, DEAD box protein 43
, DEAD box protein HAGE
, DEAD-box protein 43
, cancer/testis antigen 13
, helical antigen