anti-DEP Domain Containing 2 Antibodies

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP.

Data Quality
  • 2
Type
  • 12
    Primary antibodies
Antigen
  • 12
Reactivity
  • 12
  • 5
  • 1
  • 1
  • 1
Application
  • 9
  • 7
  • 1
  • 1
Host
  • 9
  • 3
Clonality
  • 12
Binding Specificity
  • 4
  • 3
  • 2
  • 1
  • 1
Conjugate
  • 7
  • 2
  • 2
  • 1
Isotype
  • 8
Format
  • 9
  • 1
Suggested next Filters
12 Products
ReactivityCow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2791874
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN529238
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, WB
Order details Cat. No. ABIN2751157
$462.69
100 μg
Plus shipping costs $45.00
Delivery in 1 to 2 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, IF/ICC, IHC, WB
Order details Cat. No. ABIN6090029
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083294
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083296
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083298
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, WB
Order details Cat. No. ABIN5558713
$534.62
100 μg
Plus shipping costs $45.00
Delivery in 1 to 2 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, WB
Order details Cat. No. ABIN2751158
$534.62
100 μg
Plus shipping costs $45.00
Delivery in 1 to 2 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6752877
$581.17
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2340842
$625.43
50 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2598261
$837.83
50 μg
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
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DEP Domain Containing 2 (DEPDC2) Antigen Profile

Protein Summary

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase (By similarity).

Gene names and symbols associated with DEPDC2

  • phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 (PREX2) antibody
  • phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (Prex2) antibody
  • 6230420N16Rik antibody
  • AI316880 antibody
  • AI553603 antibody
  • C030045D06Rik antibody
  • D430013K02 antibody
  • DEP.2 antibody
  • Depdc2 antibody
  • P-Rex2 antibody

Protein level used designations for DEPDC2

DEP domain-containing protein 2 , PtdIns(3,4,5)-dependent Rac exchanger 2 , phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein , DEP domain containing 2 , ptdIns(3,4,5)-dependent Rac exchanger 2

GENE ID SPECIES
80243 Homo sapiens
109294 Mus musculus
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