anti-Dachsous 1 (Drosophila) (DCHS1) Antibodies

DCHS1 is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCHS1 308912  
DCHS1 233651  
DCHS1 8642 Q96JQ0
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Top anti-DCHS1 Antibodies at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti DCHS1 Polyclonal Antibody, Unconjugated (ABIN1385853) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin-embedded human colon carcinoma labeled with Anti-DCHS1 Polyclonal Antibody, Unconjugated (ABIN1385853) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IF/ICC, WB 100 μg Log in to see 11 to 16 Days
$383.76
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: DCHS1 Antibody [NBP2-13901] - Staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells. Immunocytochemistry/Immunofluorescence: DCHS1 Antibody - Staining of human cell line HUVEC TERT2 shows localization to plasma membrane. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Hamster Goat Un-conjugated ELISA   100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, WB   100 μL Log in to see 13 to 16 Days
$500.28
Details
Mouse Goat Un-conjugated ELISA   100 μg Log in to see 11 to 13 Days
$382.67
Details

More Antibodies against DCHS1 Interaction Partners

Zebrafish Dachsous 1 (Drosophila) (DCHS1) interaction partners

  1. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis.

  2. zebrafish Dchs1b is required for atrioventricular canal development

Mouse (Murine) Dachsous 1 (Drosophila) (DCHS1) interaction partners

  1. Dchs1-Fat4 planar cell polarity pathway controls cell orientation in the early skeletal condensation to define the shape and relative dimensions of the mouse sternum.

  2. Fat4 and Dachsous1 are critical regulators of lymphatic valve morphogenesis.

  3. novel mechanisms of Fat4-Dchs1 signalling have evolved to control cell proliferation within the developing vertebrae.

  4. Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

  5. Dchs1 is a Fat4 receptor in stromal signaling essential for kidney development.

  6. DCHS1 deficiency in mitral valve prolapse patient mitral valve interstitial cells (MVICs), as well as in Dchs1(+/-) mouse MVICs, result in altered migration and cellular patterning, supporting these processes as aetiological underpinnings for the disease

  7. These findings suggest that Fat and Dachsous self-bend due to the loss of Ca(2+)-binding amino acids from specific EC-EC linkers, and can therefore adapt to confined spaces.

  8. Dchs1 and Fat4 function as a ligand-receptor pair during murine development, and novel requirements for Dchs1-Fat4 signaling in multiple organs are identified

  9. data are compatible with conservation and sub-functionalization of dachsous 1, Fj, and Fat signaling in higher vertebrates

  10. Results highlight the importance of the Fat4-Dachsous1-Pals1 complex in organizing the apical membrane architecture of neural progenitor cells.

Human Dachsous 1 (Drosophila) (DCHS1) interaction partners

  1. p.R2330C and p.R2513H were not identified in this cohort. found eight missense variants including six considered deleterious. This includes one novel variant (p.A2464P) and two rare variants (p.R2770Q and p.R2462Q). These variants are predicted to be deleterious with combined annotation-dependent depletion (CADD) scores greater than 25, which are in the same range as p.R2330C (CADD = 28.0) and p.R2513H (CADD = 24.3).

  2. The infant was diagnosed with van Maldergem syndrome on the basis of the clinical features and this was subsequently confirmed with genetic analysis, which indicated a homozygous mutation (c.7204G>A p. D2402N ) in the DCHS1 gene

  3. Study shows that when key regulators during mammalian cerebral cortical development are disrupted due to DCHS1-FAT4 mutations, functional cerebral asymmetries are stronger.

  4. In sum, we establish Dchs1 as a component of the membrane domain surrounding the ciliary base. This suggests a specific role of Dchs1 in PCP-dependent organization of ciliary function and a possible role in lung disease.

  5. DCHS1 deficiency in mitral valve prolapse patient mitral valve interstitial cells (MVICs), as well as in Dchs1(+/-) mouse MVICs, result in altered migration and cellular patterning, supporting these processes as aetiological underpinnings for the disease

  6. These findings suggest that Fat and Dachsous self-bend due to the loss of Ca(2+)-binding amino acids from specific EC-EC linkers, and can therefore adapt to confined spaces.

  7. findings show that mutations in genes encoding the receptor-ligand cadherin pair DCHS1 and FAT4 lead to a recessive syndrome in humans that includes periventricular neuronal heterotopia

DCHS1 Antigen Profile

Protein Summary

This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing.

Gene names and symbols associated with DCHS1

  • dachsous cadherin-related 1 (Dchs1) antibody
  • dachsous cadherin-related 1 (DCHS1) antibody
  • dachsous cadherin-related 1b (dchs1b) antibody
  • protocadherin-16 (LOC100447453) antibody
  • dachsous 1 (Drosophila) (Dchs1) antibody
  • 3110041P15Rik antibody
  • C130033F22Rik antibody
  • CDH25 antibody
  • CDHR6 antibody
  • dchs1 antibody
  • FIB1 antibody
  • Gm165 antibody
  • im:7136458 antibody
  • im:7156059 antibody
  • PCDH16 antibody
  • pcdh16l antibody

Protein level used designations for DCHS1

dachsous 1 , dachsous 1 (Drosophila) , protocadherin-16-like , cadherin-19 , cadherin-25 , cadherin-related family member 6 , fibroblast cadherin 1 , fibroblast cadherin FIB1 , fibroblast cadherin-1 , protein dachsous homolog 1 , protocadherin 16 , protocadherin-16

GENE ID SPECIES
308912 Rattus norvegicus
476837 Canis lupus familiaris
515576 Bos taurus
100055264 Equus caballus
419073 Gallus gallus
451001 Pan troglodytes
553300 Danio rerio
711938 Macaca mulatta
100030982 Monodelphis domestica
100357034 Oryctolagus cuniculus
100447453 Pongo abelii
100601098 Nomascus leucogenys
100623166 Sus scrofa
233651 Mus musculus
8642 Homo sapiens
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