Deleted In Azoospermia 4 Proteins (DAZ4)

DAZ4 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Additionally we are shipping Deleted In Azoospermia 4 Antibodies (56) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DAZ4 57135 Q86SG3
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Top Deleted In Azoospermia 4 Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days

DAZ4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Deleted In Azoospermia 4 (DAZ4) Interaction Partners

Human Deleted In Azoospermia 4 (DAZ4) interaction partners

  1. study reported a new type of AZFc deletion (gr/gr-DAZ2-DAZ4-CDY1b) and hypothesis that this new deletion is the result of 2 successive events favored by the unstable structure of AZFc region; also demonstrated that this deletion constitutes a relative high-risk factor for male infertility in Tunisian population

  2. Studies indicate that partial RNA-binding proteins DAZ1/2 deletion was associated wih male infertility, but partial RNA-binding proteins DAZ3/4 deletion was not associated with male infertility.

  3. Oligospermia seems to be promoted by removing DAZ4 copy. Deletion of DAZ2 and DAZ4 gene copies is associated with male infertility.

  4. a common variant of the human Y chromosome lacks the DAZ3/DAZ4 and BPY2.2/BPY2.3 doublets in distal AZFc and thus these genes cannot be required for male fertility

  5. AZFc subdeletions do not seem to cause severe impairment of spermatogenesis in Chilean men.

  6. All four DAZ genes are expressed in the human testis, and their products are highly polymorphic among men

Deleted In Azoospermia 4 (DAZ4) Protein Profile

Protein Summary

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications\; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat\; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified\; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with DAZ4

  • deleted in azoospermia 4 (DAZ4)
  • DAZ4 protein
  • pDP1680 protein
  • pDP1681 protein

Protein level used designations for DAZ4

deleted in azoospermia protein 4 , deleted in azoospermia 4

57135 Homo sapiens
749910 Pan troglodytes
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