Deoxyribonuclease I-Like 3 (DNASE1L3) ELISA Kits

DNASE1L3 encodes a member of the deoxyribonuclease I family. Additionally we are shipping DNASE1L3 Antibodies (50) and DNASE1L3 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNASE1L3 1776 Q13609
DNASE1L3 116687 O89107
DNASE1L3 13421 O55070
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Top DNASE1L3 ELISA Kits at

Showing 3 out of 16 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 5.86 pg/mL 23.44-1500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Mouse 0.054 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
  96 Tests Log in to see 11 to 18 Days

More ELISA Kits for DNASE1L3 Interaction Partners

Human Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. The authors found a significant reduction in serum DNase1l3 level in dermatomyositis/polymyositis and systemic lupus erythematosus, which may associate with clinic features and disease activity.

  2. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1, DNASE1L3, and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  3. Data indicate a likely functional variant influencing scleroderma susceptibility at deoxyribonuclease I-like 3 protein DNASE1L3 missense polymorphism rs35677470.

  4. Single nucleotide polymorphisms in the DNASE1L3 is associated with autoimmune diseases.

  5. DNASE1L3 mutations occur in hypocomplementemic urticarial vasculitis syndrome.

  6. These results suggest a cooperative activity between CAD and DNAS1L3 to accomplish internucleosomal DNA fragmentation .

  7. We identified a rare autosomal recessive form of systemic lupus erythematosus, in which autozygome analysis revealed a null mutation in the DNASE1L3 gene

  8. investigates the distribution of DNASE1L3 gene SNPs in exons of the gene in eight Asian, three African, and three Caucasian populations worldwide using newly devised genotyping methods.

  9. The Poly(ADP-ribose) polymerase-1-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells.

  10. Identification of two functional nuclear localization signals in DNase gamma that have a role in apoptotic DNA fragmentation.

  11. DNase gamma is involved in the generation of resected double-strand DNA breaks associated with somatic hypermutation

  12. DNAS1L3 plays an active role in lymphoma cell sensitization to VP-16 and its deficiency may constitute a novel mechanism of drug resistance in these cells

  13. A Caucasian-specific allele in SNP R206C produces an inactive form of DNase Il3.

  14. Results distinguish DNase gamma-dependent and CAD/DFF40-dependent DNA fragmentations, and show that even if DNA fragmentation is initiated by CAD/DFF40, DNase gamma is required for the more complete digestion of the genomic DNA in dying cells.

Xenopus laevis Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. Cloning and apoptotic DNase activity of Xenopus laevis DNase gamma

Mouse (Murine) Deoxyribonuclease I-Like 3 (DNASE1L3) interaction partners

  1. These results support a distinct role of DNASE1L3 as a regulator of the physical form and availability of cell-free DNA and may have important implications for the mechanism whereby this enzyme prevents autoimmunity.

  2. DNase1 and DNase1-like 3 are independently expressed and thus provide dual host protection against deleterious effects of intravascular neutrophil extracellular traps.

  3. Study reports that DNASE1L3-deficient mice rapidly develop autoantibodies to DNA and chromatin, followed by an systemic lupus erythematosus-like disease. Circulating DNASE1L3 is produced by dendritic cells and macrophages, and its levels inversely correlate with anti-DNA antibody response.

  4. DNase gamma, but not CAD, is the effector endonuclease for INDF in cells undergoing necrosis.

  5. A comparison of the expression and transport of DNAse1 from rats and DNAse1L3 from mice is reported.

  6. These results suggest that DNasegamma provides an alternative mechanism for inducing nuclear changes when the working apoptotic cascade is unsuitable for caspase-activated DNase activation.

  7. serum contains two nucleases, DNase1 and DNase1l3, which may substitute or cooperate with each other during DNA degradation, providing effective clearance after exposure or release from dying cells.

DNASE1L3 Antigen Profile

Antigen Summary

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with DNASE1L3

  • deoxyribonuclease 1 like 3 (DNASE1L3) antibody
  • deoxyribonuclease 1-like 3 (Dnase1l3) antibody
  • deoxyribonuclease I-like 3 S homeolog (dnase1l3.S) antibody
  • deoxyribonuclease I-like 3 (dnase1l3) antibody
  • Dhp2 antibody
  • dnas1l3 antibody
  • DNasegamma antibody
  • drng-a antibody
  • Lsd antibody
  • MGC64241 antibody
  • MGC76250 antibody
  • MGC89816 antibody
  • SLEB16 antibody

Protein level used designations for DNASE1L3

DNase I homolog protein 2 , DNase I homolog protein DHP2 , DNase I-like 3 , DNase gamma , LS-DNase , Liver and spleen DNase , deoxyribonuclease I-like III , deoxyribonuclease gamma , DNaseY , deoxyribonuclease I-like 3 , deoxyribonuclease 1-like 3 , DNase-gamma , liver and spleen DNase , macrophage specific DNase I

1776 Homo sapiens
116687 Rattus norvegicus
379439 Xenopus laevis
394515 Xenopus (Silurana) tropicalis
416008 Gallus gallus
460477 Pan troglodytes
476576 Canis lupus familiaris
512512 Bos taurus
702613 Macaca mulatta
100225960 Taeniopygia guttata
13421 Mus musculus
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