Desmoglein 4 (DSG4) ELISA Kits

DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. Additionally we are shipping Desmoglein 4 Antibodies (40) and Desmoglein 4 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DSG4 147409 Q86SJ6
DSG4 16769 Q7TMD7
DSG4 291754 Q6W3B0
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Top Desmoglein 4 ELISA Kits at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human
  96 Tests Log in to see 21 to 31 Days
$796.95
Details
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Mouse < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details

More ELISA Kits for Desmoglein 4 Interaction Partners

Human Desmoglein 4 (DSG4) interaction partners

  1. Case Report: autosomal recessive keratosis pilaris atrophicans caused by mutation in DSG4.

  2. This study further extends the body of evidence that mutations in the DSG4 gene result in both hypotrichosis and monilethrix-like scalp hair.

  3. Genetic analysis of striate palmoplantar keratoderma and hypotrichosis identified their responsible genes as desmogleins 1 and 4, respectively.

  4. Epitopes of Dsg4 may play a role in the pathogenesis of pemphigus vulgaris .

  5. show that HOXC13, LEF1 and FOXN1 repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  6. the human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.

  7. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. We also show that DSG4 is an autoantigen in pemphigus vulgaris.

  8. DSG4 is pathogenic in pemphigus and staphylococcal scalded skin syndrome.

  9. A large, intragenic deletion in the desmoglein 4 gene (DSG4) is the underlying mutation in an autosomal recessive form of hypotrichosis.

  10. The DSG4 protein is expressed in the more highly differentiated layers of the epidermis.

  11. identification of a single nucleotide deletion within exon 3 of DSG4, designated 87delG in a Pakistani family with localized autosomal recessive hypotrichosis; this results in a frameshift and premature termination codon 162 bp downstream of the deletion

Mouse (Murine) Desmoglein 4 (DSG4) interaction partners

  1. show that HOXC13, LEF1 and FOXN1 repress DSG4 transcription and provide in vitro and in vivo evidence correlating the Notch pathway with the activation and/or maintenance of DSG4 expression in the hair follicle.

  2. Desmogleins 4, 5, and 6 are all expressed in the epidermis but are expressed during different times of mouse development.

  3. The abnormal hair follicles in the mutant mice develop an amorphous keratinized bleb at the bulb of the hair follicle.

  4. Mast cell hyperplasia is associated with Dsg4-deficient hypotrichosis mice.

  5. Smad4 loss-associated Dsg4 depletion contributed, at least in part, to hair follicles degeneration in Smad4 deficient skin.

Desmoglein 4 (DSG4) Antigen Profile

Antigen Summary

This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Desmoglein 4 (DSG4) ELISA Kits

  • desmoglein 4 (DSG4) antibody
  • desmoglein-4 (LOC100543458) antibody
  • desmoglein 4 (Dsg4) antibody
  • CDGF13 antibody
  • CDHF13 antibody
  • DSG4 antibody
  • lah antibody

Protein level used designations for Desmoglein 4 (DSG4) ELISA Kits

desmoglein 4 , desmoglein-4-like , CDH family member 13 , cadherin family member 13 , desmoglein-4 , lanceolate hair

GENE ID SPECIES
537755 Bos taurus
612592 Canis lupus familiaris
743297 Pan troglodytes
100065957 Equus caballus
100414081 Callithrix jacchus
100454393 Pongo abelii
100468693 Ailuropoda melanoleuca
100543458 Meleagris gallopavo
100591286 Nomascus leucogenys
147409 Homo sapiens
16769 Mus musculus
291754 Rattus norvegicus
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