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EF-Hand Domain Family, Member D2 (EFHD2) ELISA Kits

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Additionally we are shipping EF-Hand Domain Family, Member D2 Antibodies (48) and EF-Hand Domain Family, Member D2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EFHD2 79180 Q96C19
EFHD2 298609 Q4FZY0
EFHD2 27984  
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Top EF-Hand Domain Family, Member D2 ELISA Kits at antibodies-online.com

Showing 4 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse
  96 Tests Log in to see 11 to 18 Days
$653.82
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Rat
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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More ELISA Kits for EF-Hand Domain Family, Member D2 Interaction Partners

Human EF-Hand Domain Family, Member D2 (EFHD2) interaction partners

  1. Data demonstrate that EFhd2 shows unique structural and biological features as an EF-hand containing F-actin bundling protein. For F-actin bundling activity, structural stabilization of the EF-hand domains was found to occur in the presence of Ca2+. The core region of EFhd2 maintains its structure in the absence of Ca2+ ; however, changes in local conformational flexibility reduce F-actin bundling activity of EFhd2.

  2. Phosphorylation at Ser183 of EFhd2 causes changes in the local conformational dynamics and the surface charge distribution of the actin-binding site, resulting in a re-coordination of the actin-binding sites in the dimer structure.

  3. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state.

  4. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia.

  5. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity.

  6. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  7. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  8. the human Shu complex (hSWS1.SWSAP1) has an evolutionarily conserved function in homologous recombination

  9. This protein has been found differentially expressed in thalami from patients with schizophrenia.

  10. Its predominant presence in CD8 lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes.

  11. These results suggest that swiprosin-1 is a PKC-beta I/eta-inducible gene and it modulates mast cell activation through NF-kappaB-dependent pathway.

  12. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia.

EF-Hand Domain Family, Member D2 (EFHD2) Antigen Profile

Antigen Summary

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity).

Gene names and symbols associated with EFHD2

  • EF-hand domain family member D2 (EFHD2) antibody
  • EF-hand domain family, member D2 (Efhd2) antibody
  • EF-hand domain family member D2 (efhd2) antibody
  • EF-hand domain family member D2 L homeolog (efhd2.L) antibody
  • EF hand domain containing 2 (Efhd2) antibody
  • EF-hand domain family, member D2 (efhd2) antibody
  • 2600015J22Rik antibody
  • AA408606 antibody
  • D4Wsu27e antibody
  • EFHD2 antibody
  • MGC131292 antibody
  • si:dkey-72l14.9 antibody
  • SWS1 antibody
  • wu:fb80e07 antibody

Protein level used designations for EFHD2

EF hand domain containing 2 , EF hand domain family, member D2 , EF-hand domain-containing protein D2 , swiprosin 1 , swiprosin-1 , EF-hand domain family, member D2

GENE ID SPECIES
79180 Homo sapiens
298609 Rattus norvegicus
430669 Gallus gallus
496711 Xenopus (Silurana) tropicalis
514259 Bos taurus
694155 Macaca mulatta
735013 Xenopus laevis
747200 Pan troglodytes
100345208 Oryctolagus cuniculus
27984 Mus musculus
100380618 Salmo salar
571114 Danio rerio
607254 Canis lupus familiaris
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