EF-Hand Domain Family, Member D2 (EFHD2) ELISA Kits

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Additionally we are shipping EF-Hand Domain Family, Member D2 Antibodies (47) and EF-Hand Domain Family, Member D2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EFHD2 79180 Q96C19
EFHD2 298609 Q4FZY0
EFHD2 27984  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top EF-Hand Domain Family, Member D2 ELISA Kits at antibodies-online.com

Showing 4 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse
  96 Tests Log in to see 11 to 18 Days
$653.82
Details
Rat
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for EF-Hand Domain Family, Member D2 Interaction Partners

Human EF-Hand Domain Family, Member D2 (EFHD2) interaction partners

  1. Data demonstrate that EFhd2 shows unique structural and biological features as an EF-hand containing F-actin bundling protein. For F-actin bundling activity, structural stabilization of the EF-hand domains was found to occur in the presence of Ca2 (show CA2 ELISA Kits)+. The core region of EFhd2 maintains its structure in the absence of Ca2 (show CA2 ELISA Kits)+ ; however, changes in local conformational flexibility reduce F-actin bundling activity of EFhd2.

  2. Phosphorylation at Ser183 of EFhd2 causes changes in the local conformational dynamics and the surface charge distribution of the actin-binding site, resulting in a re-coordination of the actin-binding sites in the dimer structure.

  3. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state.

  4. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia.

  5. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity.

  6. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (show CFL1 ELISA Kits) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  7. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  8. the human Shu complex (hSWS1.SWSAP1) has an evolutionarily conserved function in homologous recombination

  9. Its predominant presence in CD8 (show CD8A ELISA Kits) lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes.

  10. These results suggest that swiprosin-1 is a PKC-beta (show PRKCB ELISA Kits) I/eta-inducible gene and it modulates mast cell activation through NF-kappaB (show NFKB1 ELISA Kits)-dependent pathway.

Mouse (Murine) EF-Hand Domain Family, Member D2 (EFHD2) interaction partners

  1. These results indicate that swiprosin-1 in the vestibular nuclei is a critical determinant of the susceptibility to motion sickness.

  2. this study shows that EFhd2/swiprosin-1 regulates LPS (show TLR4 ELISA Kits)-induced macrophage recruitment via enhancing actin polymerization and cell migration

  3. These results show that EFhd2 is not essential for platelet function in mice indicating that other cytoskeletal adaptors may functionally compensate its loss.

  4. EFhd2 is a neuronal protein that interferes with kinesin-mediated transport.

  5. a role is found for EFhd2 as a negative regulator of germinal center-dependent humoral type 2 immunity, with implications for the generation of IgE.

  6. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin (show CFL1 ELISA Kits) through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183

  7. Characterized EFhd2's calcium binding activity. Results showed mutations of a conserved aspartate on either EF-hand motif disrupted calcium binding activity, indicating that these motifs work in pair as a functional calcium binding domain.

  8. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration.

  9. Swip-1 provides a membrane scaffold that is required for the Syk (show SYK ELISA Kits)-, SLP-65 (show BLNK ELISA Kits)-, and PLCgamma2 (show PLCG2 ELISA Kits)-dependent BCR (show BCR ELISA Kits)-induced calcium flux.

  10. study shows that swiprosin-1 may regulate lifespan and BCR (show BCR ELISA Kits) signaling thresholds in immature B cells

EF-Hand Domain Family, Member D2 (EFHD2) Antigen Profile

Antigen Summary

May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity).

Gene names and symbols associated with EFHD2

  • EF-hand domain family member D2 (EFHD2) antibody
  • EF-hand domain family, member D2 (Efhd2) antibody
  • EF-hand domain family member D2 (efhd2) antibody
  • EF-hand domain family member D2 L homeolog (efhd2.L) antibody
  • EF hand domain containing 2 (Efhd2) antibody
  • EF-hand domain family, member D2 (efhd2) antibody
  • 2600015J22Rik antibody
  • AA408606 antibody
  • D4Wsu27e antibody
  • EFHD2 antibody
  • MGC131292 antibody
  • si:dkey-72l14.9 antibody
  • SWS1 antibody
  • wu:fb80e07 antibody

Protein level used designations for EFHD2

EF hand domain containing 2 , EF hand domain family, member D2 , EF-hand domain-containing protein D2 , swiprosin 1 , swiprosin-1 , EF-hand domain family, member D2

GENE ID SPECIES
79180 Homo sapiens
298609 Rattus norvegicus
430669 Gallus gallus
496711 Xenopus (Silurana) tropicalis
514259 Bos taurus
694155 Macaca mulatta
735013 Xenopus laevis
747200 Pan troglodytes
100345208 Oryctolagus cuniculus
27984 Mus musculus
100380618 Salmo salar
571114 Danio rerio
607254 Canis lupus familiaris
Selected quality suppliers for EF-Hand Domain Family, Member D2 (EFHD2) ELISA Kits
Did you look for something else?