Early Growth Response 3 Proteins (EGR3)

EGR3 encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. Additionally we are shipping EGR3 Antibodies (65) and EGR3 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EGR3 1960 Q06889
EGR3 13655 P43300
EGR3 25148 P43301
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Top EGR3 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2 to 3 Days
$814.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,067.17
Details

EGR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Early Growth Response 3 (EGR3) Interaction Partners

Human Early Growth Response 3 (EGR3) interaction partners

  1. KSRP (show KHSRP Proteins) decreased EGR3 mRNA stability in an ARE-independent manner.

  2. miR (show MLXIP Proteins)-718 acts as a tumor suppressive microRNA in hepatocellular carcinoma via regulating the expression of EGR3, which may provide a new diagnostic marker and treatment target for HCC (show FAM126A Proteins)

  3. Egr2 (show EGR2 Proteins) and Egr3 have emerged as regulatory molecules that suppress excessive immune responses. Mice deficient for Egr2 (show EGR2 Proteins) and Egr3 develop a lupus-like disease with dysregulated activation of effector T cells. Egr2 (show EGR2 Proteins) and Egr3 confer suppressive activity to CD4 (show CD4 Proteins)(+) T cells and regulate the production of inhibitory cytokines such as IL-10 (show IL10 Proteins) and TGF-beta1 (show TGFB1 Proteins).

  4. EGR3 contributes to cell growth inhibition via upregulation of FasL (show FASL Proteins) in Hepatocellular carcinoma.

  5. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2 (show NR4A2 Proteins))early growth response (EGR)2 (show EGR2 Proteins) and NR4A2EGR3. Therefore, RUNX1 (show RUNX1 Proteins), NR4A2 (show NR4A2 Proteins), EGR2 (show EGR2 Proteins), EGR3 and ID4 (show ID4 Proteins) may be key genes associated with the pathogenesis of DS.

  6. These findings support previously reported associations between EGR3 and schizophrenia.

  7. EGR3 promotes excessive production of IL6 (show IL6 Proteins) and IL8 (show IL8 Proteins) observed during the progression of prostate cancer.

  8. Data shows association of Egr3 genetic polymorphisms and coronary artery disease in the Uygur and Han of China

  9. Genetic variation in EGR3 may affect prefrontal function through neurodevelopment

  10. These results provide the first evidence that Egr-3, is up-regulated in scleroderma and is necessary and sufficient for profibrotic responses.

Mouse (Murine) Early Growth Response 3 (EGR3) interaction partners

  1. Egr2 (show EGR2 Proteins) and Egr3 expressed in T cells cooperatively prevent humoral immune responses by supporting TGF-beta3 (show TGFB3 Proteins) secretion.

  2. Study demonstrates in mice that explored novel spatial environments, the involvement of Egr3 in regulating the late protein-dependent phase of Arc (show NOL3 Proteins) expression in the dentate gyrus.

  3. Egr2 (show EGR2 Proteins) and 3 are upstream regulators of effector CD4 (show CD4 Proteins) and CD8 (show CD8A Proteins) T cells that are essential for optimal responses with limited immunopathology.

  4. Egr2 and 3 are antagonists of T-bet function in effector T cells and are important for the control of inflammatory responses of T cells.

  5. Egr3 knockout mice, lacking muscle spindles, but not Golgi tendon organs, displayed a less severe prepubertal scoliosis.

  6. Egr3 is involved in myoblast proliferation by interaction with survival signaling.

  7. Study showed that acute stress activates 5-HT2AR expression in the mouse cortex and this activation requires the immediate early (show JUN Proteins) gene Egr3

  8. demonstrate a novel function of EGR2 (show EGR2 Proteins)/3 that is important for Tfh cell development and Tfh cell-mediated B cell immune responses

  9. Gene expression profiling and further functional validation revealed that Egr3 was a strong limiting factor for the proliferative potential of hematopoietic stem cells in leukemia.

  10. Egr3 overexpression in medium spiny neurons subtypes oppositely mediates behavioral responses to cocaine. Egr3 regulates cocaine-associated genes transcriptionally

Medaka Early Growth Response 3 (EGR3) interaction partners

  1. Expression of both the egr1 (show EGR1 Proteins) and egr3 mRNAs were observed in the telencephalon, hypothalamus, and optic tectum, however, the positions at which the genes were expressed were different.

EGR3 Protein Profile

Protein Summary

This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with Early Growth Response 3 Proteins (EGR3)

  • early growth response 3 (EGR3)
  • early growth response 3 (Egr3)
  • early growth response 3 (egr3)
  • EGR-3 protein
  • Pilot protein
  • zgc:92020 protein

Protein level used designations for Early Growth Response 3 Proteins (EGR3)

early growth response protein 3 , zinc finger protein pilot , EGR-3 , early growth response 3 , early growth response protein 3-like

GENE ID SPECIES
1960 Homo sapiens
13655 Mus musculus
25148 Rattus norvegicus
464048 Pan troglodytes
526233 Bos taurus
100272164 Oryzias latipes
100414808 Callithrix jacchus
436920 Danio rerio
486121 Canis lupus familiaris
100057675 Equus caballus
100516296 Sus scrofa
100728858 Cavia porcellus
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