anti-F-Box Protein 45 (FBXO45) Antibodies

Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. Additionally we are shipping FBXO45 Kits (18) and FBXO45 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FBXO45 200933 P0C2W1
FBXO45 268882 Q8K3B1
FBXO45    
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Top anti-FBXO45 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FBXO45 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell 100 μL 2 to 3 Days
$319.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunohistochemical staining of human thyroid with FBXO45 polyclonal antibody shows strong cytoplasmic and nuclear positivity in glandular cells. Immunofluorescent staining of human cell line A-431 with FBXO45 polyclonal antibody at 1-4 ug/mL dilution shows positivity in cytoplasm. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit HRP IHC (p), WB   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit FITC IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL 14 to 21 Days
$416.90
Details

More Antibodies against FBXO45 Interaction Partners

Human F-Box Protein 45 (FBXO45) interaction partners

  1. Genetic variations in FBXO45 are associated with emotional expression.

  2. FBXO45 does not simply function in substrate recognition but is important for assembly of the PAM/FBXO45/SKP1 complex.

  3. Relatively low FBXO45 expression in gastric cancer tissues is associated with cancer progression and constitutes an independent prognostic factor

  4. Data show that epithelial-mesenchymal transition (EMT)-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 (SPFFbxo45).

  5. Fbxo45 is the substrate-receptor subunit of a functional E3 ligase for Par-4 that has a critical role in cancer cell survival.

  6. Study found that the R108C mutation in FBXO45 is a rare variant with a modest effect on schizophrenia risk that may disrupt the structure and function of the FBXO45 protein

  7. FBXO45 gene consisting of 3 exons, and the vicinity of the transcriptional start site had several estrogen receptor binding consensus sequences.

  8. FBXO45 promotes the proteasome-dependent degradation of p73.

Mouse (Murine) F-Box Protein 45 (FBXO45) interaction partners

  1. Fbxo45 binds to N-cadherin intracellularly and prevents its degradation thereby playing a key role in promoting N-cadherin-mediated neuronal differentiation.

  2. Data suggest that Fbxo45 plays an important role in the regulation of neurotransmission by modulating Munc13-1 at the synapse.

  3. Results suggest that Fbxo45 forms a novel Fbxo45-PAM ubiquitin ligase complex that plays an important role in neural development.

FBXO45 Antigen Profile

Protein Summary

Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004

Gene names and symbols associated with FBXO45

  • F-box protein 45 (FBXO45) antibody
  • F-box protein 45 (fbxo45) antibody
  • F-box protein 45 (Fbxo45) antibody
  • F-box protein 45 S homeolog (fbxo45.S) antibody
  • 3g27 antibody
  • 2610017J04Rik antibody
  • AI463119 antibody
  • BC026799 antibody
  • Fbx45 antibody
  • zgc:65875 antibody

Protein level used designations for FBXO45

F-box protein 45 , F-box/SPRY domain-containing protein 1 , F-box only protein 45 , hFbxo45 , mFbxo45 , cyclin-like F-box and SPla/RYanodine receptor SPRY (36.8 kD) (3G27)

GENE ID SPECIES
471091 Pan troglodytes
533064 Bos taurus
100216147 Xenopus (Silurana) tropicalis
100340768 Oryctolagus cuniculus
200933 Homo sapiens
268882 Mus musculus
393567 Danio rerio
380431 Xenopus laevis
770111 Gallus gallus
488031 Canis lupus familiaris
100714245 Cavia porcellus
101123179 Ovis aries
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