anti-F-Box and Leucine-Rich Repeat Protein 4 (FBXL4) Antibodies

FBXL4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping FBXL4 Kits (12) and FBXL4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FBXL4 26235 Q9UKA2
FBXL4 269514 Q8BH70
FBXL4 313101  
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Top anti-FBXL4 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-FBXL4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: COLO205 cell lysate WB Suggested Anti-FBXL4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: COLO205 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Fruit Fly Rabbit Un-conjugated WB   50 μg 11 to 13 Days
$415.84
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-FbxL4 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-FbxL4 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Lung Tissue Lysate Lane 3: HELA Cell Lysate Lane 4: PANC Cell Lysate 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of FBL5 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of FBL5 expression in HEK293T (A), mouse brain (B), mouse lung (C), rat testis (D), rat lung (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Fruit Fly Rabbit Un-conjugated WB   100 μL 2 to 3 Days
$306.90
Details
Human Mouse Un-conjugated WB Western Blot analysis of FBXL4 expression in transfected 293T cell line by FBXL4 MaxPab polyclonal antibody.Lane 1: FBXL4 transfected lysate(68.31 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB   100 μg 11 to 14 Days
$463.83
Details
Human Mouse Un-conjugated DB   50 μg 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.67 KDa) . 50 μL 11 to 12 Days
$305.71
Details

More Antibodies against FBXL4 Interaction Partners

Human F-Box and Leucine-Rich Repeat Protein 4 (FBXL4) interaction partners

  1. Study found a common genomic copy number loss at 6q16.1-16.2, containing the FBXL4 gene in prostate cancer bone metastases. Loss of FBXL4 was also detected in primary tumors and it was highly associated with prognostic factors including high Gleason score, PSA, as well as poor patient survival, suggesting that FBXL4 loss contributes to prostate cancer progression.

  2. Biallelic pathogenic variants in FBXL4 are associated with an encephalopathic mtDNA maintenance defect syndrome that is a multisystem disease.

  3. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis

  4. On clinical indication of mitochondrial encephalomyopathy, sequencing of FBXL4 should be performed, even when the activity levels of the MRC enzymes are normal

  5. A clinical pattern of early-onset encephalopathy, persistent lactic acidosis, profound muscular hypotonia and typical facial dysmorphism should prompt initiation of molecular genetic analysis of FBXL4.

  6. Mutations in FBXL4 are disease causing and establish FBXL4 as a mitochondrial protein with a possible role in maintaining mtDNA integrity and stability.

  7. These data strongly support a role for FBXL4 in controlling bioenergetic homeostasis and mtDNA maintenance.

  8. SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein

Fruit Fly (Drosophila melanogaster) F-Box and Leucine-Rich Repeat Protein 4 (FBXL4) interaction partners

  1. This study uncovered a critical molecular linkage between the circadian clock and the electrical activity of pacemaker neurons and demonstrated that CLOCK-dependent Fbxl4 expression rhythmically downregulates GABAA receptor level to increase the activity of pacemaker neurons and promote wakefulness.

  2. Calmodulin/CAMTA/Fbxl4 may mediate a long-term feedback regulation of the activity of Ca(2+)-stimulating G protein-coupled receptor, which could prevent cell damage due to extra Ca(2+) influx.

FBXL4 Antigen Profile

Protein Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.

Gene names and symbols associated with FBXL4

  • F-box and leucine rich repeat protein 4 (FBXL4) antibody
  • F box and leucine-rich-repeat gene 4 (Fbxl4) antibody
  • F-box and leucine-rich repeat protein 4 (Fbxl4) antibody
  • F-box and leucine-rich repeat protein 4 (fbxl4) antibody
  • F-box and leucine-rich repeat protein 4 (FBXL4) antibody
  • F-box/LRR-repeat protein 4 (LOC551738) antibody
  • F-box and leucine rich repeat protein 4 (fbxl4) antibody
  • F-box/RNI-like superfamily protein (AT4G15475) antibody
  • 4732456I21 antibody
  • AI836810 antibody
  • CG1839 antibody
  • dFbxl4 antibody
  • Dmel\\CG1839 antibody
  • FBL4 antibody
  • FBL5 antibody
  • FBXL4 antibody
  • GB14438 antibody
  • zgc:92297 antibody

Protein level used designations for FBXL4

F-box/LRR-repeat protein 4 , F-box and leucine-rich repeat protein 4 , CG1839-PA , Fbxl4-PA , F box and leucine-rich-repeat gene 4 , F-box/LRR-repeat protein 4-like , f-box/LRR-repeat protein 4-like

GENE ID SPECIES
26235 Homo sapiens
462894 Pan troglodytes
693683 Macaca mulatta
32378 Drosophila melanogaster
269514 Mus musculus
313101 Rattus norvegicus
421798 Gallus gallus
481932 Canis lupus familiaris
492349 Danio rerio
535452 Bos taurus
551738 Apis mellifera
100027180 Monodelphis domestica
100066051 Equus caballus
100392659 Callithrix jacchus
100457811 Pongo abelii
100468171 Ailuropoda melanoleuca
100549816 Meleagris gallopavo
100552837 Anolis carolinensis
100603611 Nomascus leucogenys
101104499 Ovis aries
827219 Arabidopsis thaliana
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