FK506 Binding Protein 10, 65 KDa Proteins (FKBP10)

The protein encoded by FKBP10 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Additionally we are shipping FK506 Binding Protein 10, 65 KDa Antibodies (65) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FKBP10 14230 Q61576
Rat FKBP10 FKBP10 360627  
FKBP10 60681 Q96AY3
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Top FK506 Binding Protein 10, 65 KDa Proteins at

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days

FKBP10 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , ,
, ,

More Proteins for FK506 Binding Protein 10, 65 KDa (FKBP10) Interaction Partners

Mouse (Murine) FK506 Binding Protein 10, 65 KDa (FKBP10) interaction partners

  1. FKBP65 regulates LH2-mediated collagen cross-linking.

  2. the altered collagen crosslinking through Fkbp10 ablation in osteoblasts primarily leads to a qualitative defect in the skeleton.

  3. FKBP10 plays a crucial role in hypertrophic scar formation and maybe a therapeutic target for hypertrophic scars.

  4. Data suggest a requirement for FKBP65 function during embryonic connective tissue development in mice; its expression is restricted postnatally in bone, ligaments and tendons.

  5. FKBP65 may act as an elastin chaperone in vivo by controlling both the coacervation and the maturation stages of its selfassembly into fibrils.

Human FK506 Binding Protein 10, 65 KDa (FKBP10) interaction partners

  1. Study identified a private pathogenic splice site mutation in FKBP10 gene with nearly full decrease in the level of FKBP10 expression in the proband and around 75% decrease in its level in the carriers of the mutation suggesting its involvement in Osteogenesis imperfect.

  2. FKBP10 interacts with collagen VI and deficiency of FKBP10 reduces lung fibroblast migration by down-regulation of collage VI synthesis.

  3. Data found novel mutations of the SERPINF1 and FKBP10 genes in Chinese families with autosomal recessive osteogenesis imperfecta

  4. an endoplasmic reticulum complex of resident chaperones that includes HSP47, FKBP65, and BiP regulating the activity of LH2.

  5. FKBP10 protein is overexpressed in renal cell carcinoma

  6. FKBP65 is linked to pyridinoline cross-linking by specifically mediating the dimerization of LH2.

  7. observed changes in activity of six rER-resident PPIases, cyclophilin B (encoded by the PPIB gene), FKBP13 (FKBP2), FKBP19 (FKBP11), FKBP22 (FKBP14), FKBP23 (FKBP7), and FKBP65 (FKBP10), due to posttranslational modifications of proline residues in the substrate.

  8. novel pathogenic mutations of FKBP10 can lead to the extremely rare type XI Osteogenesis imperfecta without contractures, which expands the genotypic spectrum of Osteogenesis imperfecta.

  9. Mutations in FKBP10, localised to chromosome 17q21, have been identified in a patient of Bruck syndrome. Additional cases are also discussed.

  10. A pathogenic change was found in the FKBP10 gene in patients with osteogenesis imperfecta.

  11. findings further extend the body of evidence that supports the importance of FKBP10 gene in the development of skeletal system

  12. Mutations in the HSP47 and FKBP65 produce a moderately severe form of Osteogenesis imperfect.

  13. CTSD, FKBP10, and SLC2A1 are novel genes that participate in the acquisition and maintenance of the adriamycin-resistant phenotype in leukemia cells.

  14. Results imply that FKBP10 mutations affect collagen indirectly, by ablating FKBP65 support for collagen telopeptide hydroxylation by lysyl hydroxylase 2, thus decreasing collagen cross-links in tendon and bone matrix.

  15. Elastin binding protein and FKBP65 modulate the kinetics of self-assembly of tropoelastin in an in vitro system.

  16. FKBP10 depletion enhances glucocerebrosidase proteostasis in Gaucher disease fibroblasts

  17. underexpression of FKBP65 protein is characteristic of high-grade serous carcinomas and this expression profile may be linked to molecular pathways associated with an unfavourable outcome in cancer patients.

  18. FKBP10 acts during procollagen maturation to contribute to molecular stability and post-translational modification of type I procollagen, without which bone mass and quality are abnormal and fractures and contractures result

  19. identified a Palestinian pedigree with moderate and lethal forms of recessive OI caused by mutations in FKBP10 or PPIB, which encode endoplasmic reticulum resident chaperone/isomerases FKBP65 and CyPB, respectively

  20. Homozygosity mapping identified FKBP10 as a candidate gene, and sequencing revealed a base pair exchange that causes a C-terminal premature stop codon in this gene.

FK506 Binding Protein 10, 65 KDa (FKBP10) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.

Gene names and symbols associated with FKBP10

  • FK506 binding protein 1A, 12kDa (fkbp1a)
  • FK506 binding protein 10 (FKBP10)
  • FK506 binding protein 10b (fkbp10b)
  • FK506 binding protein 10 L homeolog (fkbp10.L)
  • FK506 binding protein 10 (fkbp10)
  • FK506 binding protein 10 (Fkbp10)
  • AI325255 protein
  • FKBP-10 protein
  • FKBP-65 protein
  • Fkbp-rs1 protein
  • Fkbp1-rs protein
  • Fkbp6 protein
  • FKBP10 protein
  • FKBP65 protein
  • Fkbprp protein
  • hFKBP65 protein
  • MGC82987 protein
  • OI6 protein
  • OI11 protein
  • PPIASE protein
  • wu:fc27c03 protein

Protein level used designations for FKBP10

FK506 binding protein 10 , FK506 binding protein 10, 65 kDa , peptidyl-prolyl cis-trans isomerase FKBP10 , FK506-binding protein , peptidyl-prolyl cis-trans isomerase FKBP10-like , 65 kDa FK506-binding protein , 65 kDa FKBP , FK506 binding protein 6 (65 kDa) , FK506-binding protein 10 , PPIase FKBP10 , immunophilin FKBP65 , rotamase , FKBP-10 , FKBP-65

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100012883 Monodelphis domestica
100438077 Pongo abelii
100562955 Anolis carolinensis
100600793 Nomascus leucogenys
14230 Mus musculus
360627 Rattus norvegicus
60681 Homo sapiens
535310 Bos taurus
490975 Canis lupus familiaris
100511038 Sus scrofa
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