Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) ELISA Kits

FSCN1 encodes a member of the fascin family of actin-binding proteins. Additionally we are shipping Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Antibodies (200) and Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FSCN1 14086 Q61553
FSCN1 683788 P85845
FSCN1 6624 Q16658
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Top Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) ELISA Kits at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.131 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$700.00
Details
Mouse 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests 12 to 14 Days
$630.00
Details
Rat 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Chicken 0.469 ng/mL 0.781-50 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details

Top referenced Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) ELISA Kits

  1. Human FSCN1 ELISA Kit for Sandwich ELISA - ABIN414808 : Teng, Xu, Yue, Ma, Zhang, Zhao, Guo, Zhang, Gu, Wang: Serological investigation of the clinical significance of fascin in non-small-cell lung cancer. in Lung cancer (Amsterdam, Netherlands) 2013 (PubMed)

More ELISA Kits for Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Interaction Partners

Fruit Fly (Drosophila melanogaster) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture.

  2. essential for actin bundle initiation and stiffening during embryonic tracheal system development

  3. Fascin and Ena cooperate to extend and maintain robust filopodia of uniform thickness with aligned barbed ends by a unique mechanistic cycle.

  4. Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis.

  5. These data lead to the conclusion that prostaglandins regulate Fascin to control actin remodeling

  6. The terminal branchlets of different classes of neurons have distinctive dynamics and are formed on the basis of molecularly separable mechanisms; in particular, class III neurons require fascin for terminal branching whereas class IV neurons do not.

  7. The regulatory role of FascinS52 appears to be tissuespecific, and its importance might depend on the dynamics and the turnover rate of actin bundles between various cell types.

  8. Fascin deficiency does not impair 20-hydroxyecdysone response, but neurites fail to maintain their normal, nearly straight trajectory, instead forming curls and hooks. This is accompanied by abnormally distributed filamentous actin.

  9. Fascin is required for plasmatocyte migration, both as these cells undergo developmental dispersal and during an inflammatory response to epithelial wounding.

  10. study found that Rab35 regulates the assembly of actin filaments during bristle development; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35

Zebrafish Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fscn1 acts as a molecular linker between TGF-beta family type I receptors and the actin filaments to promote the trafficking of internalized receptors from clathrin-coated vesicles to early endosomes during zebrafish endoderm formation.

  2. These data show that fscn1a-dependent filopodia are required in a subset of NC cells to promote cell migration and NC derivative formation

Mouse (Murine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fascin-1 is specifically expressed in podocytes.

  2. MAGE-G1 interacted with fascin 1 or vimentin in P19 cells after a 6-day retinoic acid-induced neuronal differentiation.

  3. The data suggested that Daam1 affected actin assembly during oocyte meiotic division via the regulation of fascin expression.

  4. Filopodia formation by crosslinking of F-actin with fascin in two different binding manners

  5. Fascin-1 expression, cadherin-17 expression, tumor size, and differentiation were independent risk factors for GC.

  6. Fascin1 facilitates phagolysosomal fusion for killing of phagocytosed Listeria. It binds to LC3, an autophagosome marker, both in vivo & in vitro. It plays a critical role in dendritic cell survivalduring Listeria infection.

  7. A tightly regulated phospho/dephospho-fascin cycle modulated by extracellular signals is required for the polarized morphology and migration in neuroblasts, thus contributing to efficient neurogenesis.

  8. fascin 1 promotes cell migration and has a role in growth and cell cycle progression

  9. Suppression of fascin expression results in reduction of activation-induced migration and invasion in mouse monocytic leukemia RAW264.7 macrophages.

  10. Both STAT3 and NFkappaB are required for the cytokine-induced expression of fascin in cancer cells.

  11. Fascin1 is critical for cell migration; expression of exogenous fascin1 in fascin1-null dendritic cells (DC) rescues the defects in membrane protrusive activity, as well as in DC podosome disassembly.

  12. fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development

  13. We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.

  14. Fascin is a novel target of beta-catenin-TCF signaling and is expressed at the invasive front of human colon cancer

  15. Fascin mRNA & protein levels were significantly lower in the cultured ANXA2(-/-) cells than in cultured ANXA2(+/+) cells. ANXA2 may be an inducer or enhancer of fascin expression at the transcription level.

  16. The results indicate that fascin1-mediated filopodia assembly is dispensable for mouse development.

  17. study found that Rab35 regulates the assembly of actin filaments in filopodia formation; effect was mediated by the actin-bundling protein fascin, which directly associated with active Rab35

Human Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Fascin-1 significantly increased in AML.

  2. we found that there was a significant association between FSCN1 expression and poor relapse-free survival and overall survival. Therefore, we suggest that co-targeting epidermal growth factor receptor and FSCN1 dual biomarker may be used as a novel therapeutic strategy for triple-negative breast cancer.

  3. genetic variations in the FSCN1 gene may serve as an important predictor of early-stage breast cancer.

  4. we found that ZEB1-AS1 is a downstream target of TGF-beta1 and is involved in its regulatory mechanism on cell migration and invasion by affecting miR-200b/FSCN1 axis in bladder cancer cells

  5. Study demonstrated that Fascin-1 expression correlates with poor patient survival and can be used as an additional prognostic factor for osteosarcoma patient outcome.

  6. FSCN1 is a driver of invasiveness in renal cell carcinoma cells via PI3 K/AKT signaling axis.

  7. Through stimulation with cancerassociated fibroblasts and growth factors, study demonstrated that fascin expression was regulated by stromal factors of the microenvironment surrounding the tumor. A fascindepleted cell line showed low RhoA and NFkappaB activity suggesting that RhoA and NFkappaB signals are involved in fascin expression.

  8. Fascin is important for Rab25-induced breast and ovarian cancer invasion.

  9. esults indicate that the inhibition of autophagy and exogenous expression of fascin-1 may promote the invasiveness of endometrial cells.

  10. fascin1 constitutively interacts with IkappaB kinase (IKK) in the RIG-I signaling pathway. In summary, we have identified fascin1 as a suppressor of the RIG-I signaling pathway associating with IkappaB kinase in DLD-1 colon cancer cells to suppress immune responses to viral infection.

  11. fascin protein accumulation, caused by reduced proteasomal activity, contributes to the acquisition of cancer stemness in chronic inflammation-related colon carcinogenesis.

  12. Fascin1 is related with clinicopathologic parameters of gastric cancer and overexpressed both in gastric cell lines and gastric tumor tissue

  13. the expression of Fascin_1 protein differed between cancer tissue and paracarcinoma tissues in NSCLC patients and it was also correlated with poor prognosis.

  14. FSCN1 physiologically interacted with and increased the levels of snail1 to promote ovarian cancer cell epithelial-mesenchymal transition .

  15. fascin1 is an important mediator of TGF-beta1-induced invasion and migration of kidney carcinoma cells through ERK and JNK signal pathways.

  16. findings demonstrate that fascin is required for migration and invasion induced by LA in MDA-MB-231 breast cancer cells.

  17. PCAT-1 accelerated prostate cancer cell proliferation, migration, invasion and suppressed apoptosis by up-regulating FSCN1 mediated via miR-145-5p.

  18. Lentivirus-mediated fascin-1 knockdown significantly decreased the proliferation of non-small cell lung cancer cells. Furthermore, fascin-1 silencing partly inhibited cell invasion and migration. Inhibition of fascin-1 decreased the activity of the MAPK pathway.

  19. Study shows that Fascin 1 has a nuclear function in the regulation of the amino-acid transporter SLC3A2.

  20. SNAI2 overexpression significantly increased FSCN1 expression at both mRNA and protein level. FSCN1 overexpression reduced the expression of E-cadherin and Claudin 1, but increased the expression of Vimentin and N-cadherin in SCC9 and SCC-15 cells. It is inferred that FSCN1 is a downstream effector of SNAI2 in promoting EMT in HNSC cells.

Pig (Porcine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. FSCN1 gene plays an in prenatal skeletal muscle development and was a candidate gene for meat production trait.

Cow (Bovine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. miR-145 targeted and regulated FSCN1. Knock-down of FSCN1 significantly increased the secretion of IL-12, while the secretion of TNF-alpha was significantly downregulated in Mac-T cells.

Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antigen Profile

Antigen Summary

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Gene names and symbols associated with FSCN1

  • singed (sn) antibody
  • fascin actin-bundling protein 1 (fscn1) antibody
  • fascin actin-bundling protein 1a (fscn1a) antibody
  • fascin actin-bundling protein 1 (Fscn1) antibody
  • fascin actin-bundling protein 1 L homeolog (fscn1.L) antibody
  • fascin actin-bundling protein 1 (FSCN1) antibody
  • AI663989 antibody
  • CG1536 antibody
  • CG15331 antibody
  • CG32858 antibody
  • Dmel\\CG32858 antibody
  • FAN1 antibody
  • fascin antibody
  • fascin-1 antibody
  • fs(1)A1057 antibody
  • fs(1)K418 antibody
  • fs(1)K473 antibody
  • fs(1)K743 antibody
  • fs(1)K1421 antibody
  • fs(1)M45 antibody
  • fscn antibody
  • fscn1 antibody
  • HSN antibody
  • MGC75811 antibody
  • p55 antibody
  • sb:cb589 antibody
  • Sn antibody
  • SNL antibody
  • zgc:153632 antibody

Protein level used designations for FSCN1

CG32858-PA , CG32858-PB , CG32858-PD , CG32858-PE , CG32858-PF , CG32858-PG , fascin , sn-PA , sn-PB , sn-PD , sn-PE , sn-PF , sn-PG , fascin-1 , fascin 1 , singed-like protein , 55 kDa actin-bundling protein , singed-like (fascin homolog, sea urchin)

GENE ID SPECIES
31717 Drosophila melanogaster
394733 Xenopus (Silurana) tropicalis
558271 Danio rerio
14086 Mus musculus
683788 Rattus norvegicus
397934 Xenopus laevis
6624 Homo sapiens
489880 Canis lupus familiaris
100286741 Sus scrofa
100733694 Cavia porcellus
507342 Bos taurus
416485 Gallus gallus
101108186 Ovis aries
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