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Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) ELISA Kits

FSCN1 encodes a member of the fascin family of actin-binding proteins. Additionally we are shipping Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Antibodies (215) and Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FSCN1 14086 Q61553
FSCN1 683788 P85845
FSCN1 6624 Q16658
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Top Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) ELISA Kits at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.131 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Mouse 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) ELISA Kits

  1. Human FSCN1 ELISA Kit for Sandwich ELISA - ABIN414808 : Teng, Xu, Yue, Ma, Zhang, Zhao, Guo, Zhang, Gu, Wang: Serological investigation of the clinical significance of fascin in non-small-cell lung cancer. in Lung cancer (Amsterdam, Netherlands) 2013 (PubMed)

More ELISA Kits for Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) Interaction Partners

Fruit Fly (Drosophila melanogaster) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture.

  2. essential for actin bundle initiation and stiffening during embryonic tracheal system development

  3. Fascin and Ena cooperate to extend and maintain robust filopodia of uniform thickness with aligned barbed ends by a unique mechanistic cycle.

  4. Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis.

  5. These data lead to the conclusion that prostaglandins regulate Fascin to control actin remodeling

  6. The terminal branchlets of different classes of neurons have distinctive dynamics and are formed on the basis of molecularly separable mechanisms; in particular, class III neurons require fascin for terminal branching whereas class IV neurons do not.

  7. The regulatory role of FascinS52 appears to be tissuespecific, and its importance might depend on the dynamics and the turnover rate of actin bundles between various cell types.

  8. Fascin deficiency does not impair 20-hydroxyecdysone response, but neurites fail to maintain their normal, nearly straight trajectory, instead forming curls and hooks. This is accompanied by abnormally distributed filamentous actin.

  9. Fascin is required for plasmatocyte migration, both as these cells undergo developmental dispersal and during an inflammatory response to epithelial wounding.

  10. study found that Rab35 (show RAB35 ELISA Kits) regulates the assembly of actin (show ACTB ELISA Kits) filaments during bristle development; effect was mediated by the a (show ACTB ELISA Kits)ctin-bundling protein fascin, which directly associated with active R (show RAB35 ELISA Kits)ab35

Zebrafish Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. These data show that fscn1a-dependent filopodia are required in a subset of NC cells to promote cell migration and NC derivative formation

Mouse (Murine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. Filopodia formation by crosslinking of F-actin with fascin in two different binding manners

  2. Fascin-1 expression, cadherin-17 expression, tumor size, and differentiation were independent risk factors for GC.

  3. Fascin1 facilitates phagolysosomal fusion for killing of phagocytosed Listeria. It binds to LC3 (show MAP1LC3A ELISA Kits), an autophagosome marker, both in vivo & in vitro. It plays a critical role in dendritic cell survivalduring Listeria infection.

  4. A tightly regulated phospho/dephospho-fascin cycle modulated by extracellular signals is required for the polarized morphology and migration in neuroblasts, thus contributing to efficient neurogenesis.

  5. fascin 1 promotes cell migration and has a role in growth and cell cycle progression

  6. Suppression of fascin expression results in reduction of activation-induced migration and invasion in mouse monocytic leukemia RAW264.7 macrophages.

  7. Both STAT3 (show STAT3 ELISA Kits) and NFkappaB are required for the cytokine-induced expression of fascin in cancer cells.

  8. fascin-1 is principally expressed in neural and mesenchymal derivatives during embryonic development

  9. We propose that fascin is a key specific actin cross-linker, providing stiffness for filopodial bundles, and that its dynamic behavior allows for efficient coordination between elongation and bundling of filopodial actin filaments.

  10. Fascin is a novel target of beta-catenin (show CTNNB1 ELISA Kits)-TCF (show HNF4A ELISA Kits) signaling and is expressed at the invasive front of human colon cancer

Human Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. SNAI2 overexpression significantly increased FSCN1 expression at both mRNA and protein level. FSCN1 overexpression reduced the expression of E-cadherin (show CDH1 ELISA Kits) and Claudin 1 (show CLDN7 ELISA Kits), but increased the expression of Vimentin (show VIM ELISA Kits) and N-cadherin (show CDH2 ELISA Kits) in SCC9 and SCC (show CYP11A1 ELISA Kits)-15 cells. It is inferred that FSCN1 is a downstream effector of SNAI2 in promoting EMT (show ITK ELISA Kits) in HNSC cells.

  2. MYC (show MYC ELISA Kits)-nick, fascin, and Cdc42 (show CDC42 ELISA Kits) are frequently up-regulated in cells present at the invasive front of human colorectal tumors, suggesting a coordinated role for these proteins in tumor migration.

  3. The prognostic importance of TGF-beta (show TGFB1 ELISA Kits), TGF-beta (show TGFB1 ELISA Kits) receptor, and fascin in childhood solid tumors

  4. The results reveal that phosphorylation at FSCN1 amino acids Y23, S38, S39 and S274, in combination, downregulates the extent of anchorage-independent growth, cell migration and filopodia formation in esophageal squamous cancer cells.

  5. Fascin and alpha-actinin intrinsically segregate to discrete bundled domains that are specifically recognized by other actin-binding proteins.

  6. This study showed that fascin expression intensity may be correlated with clinical outcomes of a newly diagnosed primary glioblastoma.

  7. These data demonstrated fascin as a critical regulator of breast cancer stem cell pool at least partially via activation of the Notch (show NOTCH1 ELISA Kits) self-renewal signaling pathway.

  8. These results suggest that strong positive fascin-1 expression can be used as a diagnostic marker of TNBC.

  9. Authors demonstrated that one miRNA, miR (show MLXIP ELISA Kits)-29a-5p, can bind to both the XIAP (show XIAP ELISA Kits) and FSCN1 3'UTRs and play an important role in that interactions. We showed that the 3'UTR (show UTS2R ELISA Kits) of XIAP (show XIAP ELISA Kits) was able to antagonize miR (show MLXIP ELISA Kits)-29a-5p, and resulted in the increased translation of XIAP (show XIAP ELISA Kits) and FSCN1.

  10. The expression of fascin-1 and lanminin-5 and the serum levels of fascin-1 and laminin-5 were related to the relapse of patients with non-small cell lung cancer.

Pig (Porcine) Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) interaction partners

  1. FSCN1 gene plays an in prenatal skeletal muscle development and was a candidate gene for meat production trait.

Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus) (FSCN1) Antigen Profile

Antigen Summary

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Gene names and symbols associated with FSCN1

  • singed (sn) antibody
  • fascin actin-bundling protein 1 (fscn1) antibody
  • fascin actin-bundling protein 1a (fscn1a) antibody
  • fascin actin-bundling protein 1 (Fscn1) antibody
  • fascin actin-bundling protein 1 L homeolog (fscn1.L) antibody
  • fascin actin-bundling protein 1 (FSCN1) antibody
  • AI663989 antibody
  • CG1536 antibody
  • CG15331 antibody
  • CG32858 antibody
  • Dmel\\CG32858 antibody
  • FAN1 antibody
  • fascin antibody
  • fascin-1 antibody
  • fs(1)A1057 antibody
  • fs(1)K418 antibody
  • fs(1)K473 antibody
  • fs(1)K743 antibody
  • fs(1)K1421 antibody
  • fs(1)M45 antibody
  • fscn antibody
  • fscn1 antibody
  • HSN antibody
  • MGC75811 antibody
  • p55 antibody
  • sb:cb589 antibody
  • Sn antibody
  • SNL antibody
  • zgc:153632 antibody

Protein level used designations for FSCN1

CG32858-PA , CG32858-PB , CG32858-PD , CG32858-PE , CG32858-PF , CG32858-PG , fascin , sn-PA , sn-PB , sn-PD , sn-PE , sn-PF , sn-PG , fascin-1 , fascin 1 , singed-like protein , 55 kDa actin-bundling protein , singed-like (fascin homolog, sea urchin)

GENE ID SPECIES
31717 Drosophila melanogaster
394733 Xenopus (Silurana) tropicalis
558271 Danio rerio
14086 Mus musculus
683788 Rattus norvegicus
397934 Xenopus laevis
6624 Homo sapiens
489880 Canis lupus familiaris
100286741 Sus scrofa
100733694 Cavia porcellus
507342 Bos taurus
416485 Gallus gallus
101108186 Ovis aries
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