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FDXR encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH.
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S. pombe is either very robust to mitochondrial reactive oxygen species (ROS (show ROS1 ELISA Kits)) production or does not undergo apoptotic cell death in response to mitochondrial ROS (show ROS1 ELISA Kits) at all.
Using surface plasmon resonance, physiologically relevant concentrations of isatin (25-100 muM) were found to increase affinity of interactions between human recombinant ferrochelatase (FECH (show FECH ELISA Kits)) and NADPH (show NQO1 ELISA Kits)-dependent adrenodoxin reductase (ADR).
Mutation in FDXR gene is associated with Sensorial Neuropathies.
NOS-3 overexpression resulted in an increased sensitivity to anti-Fas (show FAS ELISA Kits) induced cell death, independently of AR expression and CatD (show CTSD ELISA Kits) activity.
These results indicated that abundant FDXR expression in these steroidogenic cells was maintained through SF-1 (show NR5A1 ELISA Kits) binding to the intronic enhancer of the FDXR gene
results suggest that both FDX1 (show FDX1 ELISA Kits) and FDX2 (show FDX1L ELISA Kits) and their likely reductase partner, FDXR, contribute to iron-sulfur cluster biogenesis
comparison of catalytic properties between conditions of limiting and saturating adrenodoxin reductase [cytochrome P450scc (show CYP11A1 ELISA Kits)]
The ferredoxin reductase gene is regulated by the p53 (show TP53 ELISA Kits) family and sensitizes cells to oxidative stress-induced (show SQSTM1 ELISA Kits) apoptosis
ADXR rate of hydroxylation was linear with incubation time.
This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene.
NADPH:adrenodoxin oxidoreductase, mitochondrial
, adrenodoxin reductase
, ferredoxin--NADP(+) reductase
, ferredoxin reductase
, ferredoxin--NADP reductase
, adrenodoxin-NADP(+) reductase
, ferredoxin reductase L homeolog