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Fibroblast Growth Factor Receptor Substrate 3 Proteins (FRS3)

The protein encoded by FRS3 is a substrate for the fibroblast growth factor receptor. Additionally we are shipping Fibroblast Growth Factor Receptor Substrate 3 Antibodies (54) and Fibroblast Growth Factor Receptor Substrate 3 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FRS3 10817 O43559
FRS3 107971 Q91WJ0
FRS3 316213 Q52RG8
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Top Fibroblast Growth Factor Receptor Substrate 3 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,389.83
Details
Baculovirus infected Insect Cells Human GST tag   20 μg Log in to see 1 to 2 Days
$309.10
Details
Baculovirus infected Insect Cells Human Un-conjugated   50 μg Log in to see 10 to 12 Days
$673.36
Details

FRS3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Fibroblast Growth Factor Receptor Substrate 3 (FRS3) Interaction Partners

Xenopus laevis Fibroblast Growth Factor Receptor Substrate 3 (FRS3) interaction partners

  1. signaling via Pax6 expression through Shp2-binding sites of XFrs3 is necessary for the eye development in Xenopus laevis

Human Fibroblast Growth Factor Receptor Substrate 3 (FRS3) interaction partners

  1. Mechanisms by which FRS2beta acts as a feedback inhibitor of EGFR family members and suggest a role for FRS2beta as a tumor suppressor.

  2. an FRS2beta-CIN85/CD2AP-Cbl axis for downregulation of ErbB2 may regulate ErbB2 protein levels in physiological and pathological settings

  3. FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors

  4. FRS2beta can compensate for the loss of FRS2alpha for activation of MAP kinase when expressed in fibroblasts

  5. SNT-2 negatively regulates ERK2 signaling activated via EGF stimulation through direct binding to ERK2

  6. Novel mechanism of negative control of EGFR tyrosine kinase activity with SNT-2 by recruiting ERK2.

Mouse (Murine) Fibroblast Growth Factor Receptor Substrate 3 (FRS3) interaction partners

  1. FRS2 and FRS3, are together required for postnatal brain development. In the hippocampus, FRS2&3 promote dentate gyrus morphogenesis and dentate granule cell (DGC) maturation during developmental neurogenesis. Frs2,3-double mutants have reduced numbers of dendritic branches and spines in DGCs. Double-mutant mice exhibit fewer excitatory synaptic inputs onto DGCs.

  2. Analysis of a mutant Fgfr1 allele, unable to bind to the adaptor protein, Frs2/3, indicates that Sox2 maintenance can be

  3. data indicate that the fibroblast growth factor receptor substrate 2 and fibroblast growth factor receptor substrate 3 adapters may have a role in thyroid carcinogenesis triggered by TRK oncogenes

  4. Some essential functions of Fgfr1 are mediated by Frs-independent signaling.

  5. ULK2, by interaction with FRS2/3 and inhibition of SynGAP, functions to negatively regulate tyrosyl phosphorylation of signaling proteins downstream of FGFR1.

  6. SNT family proteins may play significant roles in cellular transformation triggered by NPM-ALK.

  7. The results showed that the interaction of full-length FRS2beta with FGFR1 was not enhanced by activation of the receptor kinase.

  8. Prominent expression of Frs2beta protein in neural cells and its association with intracellular vesicles is reported.

Fibroblast Growth Factor Receptor Substrate 3 (FRS3) Protein Profile

Protein Summary

The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.

Gene names and symbols associated with FRS3

  • fibroblast growth factor receptor substrate 3 S homeolog (frs3.S)
  • fibroblast growth factor receptor substrate 3 (FRS3)
  • fibroblast growth factor receptor substrate 3 (frs3)
  • fibroblast growth factor receptor substrate 3 (Frs3)
  • 4930417B13Rik protein
  • AI449674 protein
  • FRS2-beta protein
  • FRS2B protein
  • Frs2beta protein
  • MGC82242 protein
  • SNT-2 protein
  • Snt2 protein

Protein level used designations for FRS3

fibroblast growth factor receptor substrate 3 , FGFR substrate 3 , FGFR-signaling adaptor SNT2 , suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) , FRS2-beta , SNT-2 , suc1-associated neurotrophic factor target 2

GENE ID SPECIES
432079 Xenopus laevis
472005 Pan troglodytes
694462 Macaca mulatta
100054379 Equus caballus
100101737 Xenopus (Silurana) tropicalis
100137210 Papio anubis
100405094 Callithrix jacchus
100450222 Pongo abelii
100579840 Nomascus leucogenys
10817 Homo sapiens
107971 Mus musculus
316213 Rattus norvegicus
481794 Canis lupus familiaris
509838 Bos taurus
100328715 Oryctolagus cuniculus
100153876 Sus scrofa
419923 Gallus gallus
100716560 Cavia porcellus
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