anti-Fras1 Related Extracellular Matrix Protein 2 (FREM2) Antibodies

FREM2 encodes a membrane protein that belongs to the FRAS1 family.

Gene Name	GeneID	UniProt
FREM2	341640	Q5SZK8
FREM2	242022	Q6NVD0
FREM2	310418

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Top anti-FREM2 Antibodies at antibodies-online.com

Showing 10 out of 29 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN570769	Please inquire	Goat	Un-conjugated	ELISA	100 μg	Log in to see	6 to 7 Days	$291.53	Details
ABIN625946	Human	Rabbit	Un-conjugated	ELISA, ICC, IHC, IHC (p), WB	50 μg	Log in to see	11 to 14 Days	$484.00	Details
ABIN2464578	Human	Goat	Un-conjugated	ELISA	0.1 mg	Log in to see	2 to 3 Days	$446.88	Details
ABIN5554374	Human	Rabbit	Un-conjugated	EIA, IF, WB	0.1 mg	Log in to see	8 to 11 Days	$474.10	Details
ABIN490614	Cow	Goat	Un-conjugated	ELISA	100 μg	Log in to see	11 to 14 Days	$507.83	Details
ABIN4312568	Human	Rabbit	Un-conjugated	IHC, IHC (p)	0.1 mL	Log in to see	10 to 13 Days	$494.38	Details
ABIN1734464	Human	Rabbit	Un-conjugated	ICC, IHC (p), ELISA, WB	50 μg	Log in to see	12 to 14 Days	$673.48	Details
ABIN784083	Human	Rabbit	Un-conjugated	EIA, IF, IHC (p), WB	50 μg	Log in to see	6 to 8 Days	$390.50	Details
ABIN5578385	Human	Rabbit	Un-conjugated	ELISA, ICC, WB	100 μg	Log in to see	11 to 12 Days	$349.54	Details
ABIN5578386	Human	Rabbit	Un-conjugated	IHC (p)	100 μL	Log in to see	11 to 12 Days	$452.00	Details

More Antibodies against FREM2 Interaction Partners

Human Fras1 Related Extracellular Matrix Protein 2 (FREM2) interaction partners

FREM2 is thus proposed as a novel GB biomarker and a putative biomarker of glioblastoma stem cells. Both FREM2 and SPRY1 are expressed on the surface of the GB cells, while SPRY1 alone was found overexpressed in the cytosol of non-malignant astrocytes.
In 15 of 590 families, we identified recessive mutations in the genes FRAS1, FREM2, GRIP1, FREM1, ITGA8, and GREM1, all of which function in the interaction of the ureteric bud and the metanephric mesenchyme.
Amplification of the FREM2 gene is associated with mesenchymal differentiation in gliosarcoma.
Heterozygous missense mutations in FREM2 cause non-syndromic congenital abnormalities of the kidney and urinary tract in humans.
report on 2 fetuses affected by Fraser syndrome (FS); a homozygous IVS14 + 1G -- A mutation in FREM2 was indentified; present report provides additional evidence that FS may be caused by complete or near-complete lack or loss of function of FREM2 protein
1 new mutation in FREM2 was identified in families with Fraser syndrome.

Mouse (Murine) Fras1 Related Extracellular Matrix Protein 2 (FREM2) interaction partners

Report Fras1 up-regulation/Frem down-regulation in nephrons from mice with polycystic kidney disease and Frem2 mutations.
The QBRICK, together with Frem2, defines the ability of BMs to bind integrin 81 through modulating the BM assembly of nephronectin, thereby regulating the integrin 81-mediated signals transmitted from the ureteric buds to the metanephric mesenchyme.
expression of Frem2 may dynamically alter the extracellular matrix to provide a substrate for cell migration and rearrangements during embryogenesis
QBRICK/Frem1, Fras1, and Frem2 interactions at the basement membrane have roles in preventing Fraser syndrome-like defects
Study reports a comparative analysis of the spatiotemporal localization of Fras1, Frem1, Frem2 and Frem3 proteins during mouse embryonic development.
Fras1 is not only essential as a component of a macromolecular complex for the extracellular stabilization of Frem2 but it is also required for its proper intracellular trafficking and export from embryonic epithelial cells.
The localization pattern of Fras1 and Frem2 was indistinguishable, while both proteins along with Frem3 could be detected even in the absence of Frem1.

FREM2 Antigen Profile

Protein Summary

This gene encodes a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes. Mutations in this gene are associated with Fraser syndrome.

Gene names and symbols associated with FREM2

FRAS1 related extracellular matrix protein 2 (FREM2) antibody
Fras1 related extracellular matrix protein 2 (Frem2) antibody

6030440P17Rik antibody
8430406N05Rik antibody
b2b1562Clo antibody
Gm409 antibody
my antibody
ne antibody
nv1 antibody
RGD1566012 antibody

Protein level used designations for FREM2

ECM3 homolog , FRAS1-related extracellular matrix protein 2 , NV domain containing protein NV1 , NV domain-containing protein 1

GENE ID	SPECIES
341640	Homo sapiens
242022	Mus musculus
310418	Rattus norvegicus
486002	Canis lupus familiaris
527601	Bos taurus

Selected quality suppliers for anti-FREM2 (FREM2) Antibodies

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