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GLIS2 is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. Additionally we are shipping GLIS2 Proteins (4) and many more products for this protein.
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Cow (Bovine) Polyclonal GLIS2 Primary Antibody for IHC, WB - ABIN2779249
Zhang, Nakanishi, Kurebayashi, Yoshino, Perantoni, Kim, Jetten: Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis. in The Journal of biological chemistry 2002
Show all 2 Pubmed References
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.
Kruppel-like zinc finger protein GLIS2
, Gli-Kruppel zinc-finger protein NKL
, GLI-similar 2
, GLI-similar protein 2
, neuronal Krueppel-like protein
, zinc finger protein GLIS2
, GLI-Kruppel family member GLI5
, Kruppel-like factor 16 (neuronal)
, zinc finger protein GLI5
, GLIS family zinc finger 2