anti-Galactokinase 1 (GALK1) Antibodies

Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. Additionally we are shipping Galactokinase 1 Proteins (65) and Galactokinase 1 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GALK1 2584 P51570
GALK1 14635  
GALK1 287835  
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Top anti-Galactokinase 1 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GALK1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Liver 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of Galactose Kinase staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Galactose Kinase expression in HEK293T (A), HepG2 (B), SP2/0 (C), rat liver (D), Human liver (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc/HeLa cells, using GALK1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Image GALK1 antibody detects GALK1 protein by Western blot analysis. A. 30 µg Huh7 whole cell lysate/extract B. 30 µg HepG2 whole cell lysate/extract 10 % SDS-PAGE GALK1 antibody , dilution: 1:1000 WB Image Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$537.17
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis on NIH-3T3 and HeLa cell lysate using GALK1 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266745 staining HuvEc by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

More Antibodies against Galactokinase 1 Interaction Partners

Human Galactokinase 1 (GALK1) interaction partners

  1. Some of the single consensus variants (M60V, D268E, A334S and G373S) increased the catalytic turnover of the enzyme, but none resulted in improved stability. When all six changes were introduced into the protein (M60V/M180V/D268E/A334S/R366Q/G373S), thermal stability was increased.

  2. Focussing on four residues (Leu-231, Gln-242, Glu-244 and Glu-245) this study conducted molecular dynamics simulations to explore the effects of changing these residues to glycine or serine. The four serine variants were expressed as recombinant proteins. All had altered steady state enzyme kinetic parameters with alpha-d-galactose as a substrate.

  3. Mutation in the GALK gene is associated with mental disorders in galactosemia.

  4. The GALK1 gene was included in this interval and direct sequencing.

  5. Data indicate taht the interactions between galactokinase (GALK) and its potential inhibitors by molecular dynamics simulations.

  6. The study highlighted the importance of GALK gene analysis in diagnosis of galactosemia in Indian population.

  7. A possible mechanism for the unfolding caused by the Pro(28)Thr point mutation of human galactokinase.

  8. Pathogenic mutations in GALK1 that are responsible for autosomal recessive congenital cataracts in consanguineous Pakistani families, are reported.

  9. 2 new GALK1 mutations near the ATP-binding site were found in a homozygotic Turkish immigrant: S142I and G148C.

  10. Has ordered ternary complex mechanism with ATP being the first substrate to bind.

  11. In this northern Italian population age-related cataract does not appear to be associated with GALK1 alleles.

  12. structure and function of galactokinase, and role in type II galactosemia [review]

  13. Structure of the human enzyme complexed with MgAMP.PNP and galactose

  14. Mutations in GALK1 resulted in reduction of GALK activity and caused GALK deficiency.

  15. These results suggest that the elevated GALK1 activity resulted from enhanced gene expression, due to nucleotide variation within GALK1 promoter

  16. The disease-causing point mutations in the human enzyme are mapped onto the structure of the protein from Pyrococcus furiosus and speculations made about the structural consequences.

  17. 2-deoxy-D-galactose is a substrate for this enzyme. D-glucose, D-fucose, L-arabinose and N-acetyl-D-galactosamine are not. Mutations H44A, H44I, E43G/H44I are insoluble, D46A is inactive, E43G has reduced activity and E43A has wild-type activity.

Mouse (Murine) Galactokinase 1 (GALK1) interaction partners

  1. Egr-1 and galactokinase have roles in a developmentally regulated chain to prepare the neonate for suckling

Galactokinase 1 (GALK1) Antigen Profile

Protein Summary

Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.

Gene names and symbols associated with anti-Galactokinase 1 (GALK1) Antibodies

  • galactokinase 1 (GALK1) antibody
  • galactokinase 1 (Galk1) antibody
  • AA409894 antibody
  • Galk antibody
  • Gk antibody
  • GK1 antibody
  • Glk antibody
  • Glk1 antibody

Protein level used designations for anti-Galactokinase 1 (GALK1) Antibodies

galactokinase 1 , galactokinase , galactose kinase

GENE ID SPECIES
100341480 Oryctolagus cuniculus
2584 Homo sapiens
14635 Mus musculus
287835 Rattus norvegicus
530855 Bos taurus
403694 Canis lupus familiaris
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