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Glutathione S-Transferase alpha 2 (GSTa2) ELISA Kits

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping Glutathione S-Transferase alpha 2 Antibodies (75) and Glutathione S-Transferase alpha 2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GSTa2 2939 P09210
GSTa2 24422 P00502
GSTa2 14858 P10648
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Top Glutathione S-Transferase alpha 2 ELISA Kits at antibodies-online.com

Showing 4 out of 16 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.125 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$700.00
Details
Rat
  96 Tests 2 to 3 Days
$867.90
Details
Mouse
  96 Tests 11 to 18 Days
$682.25
Details
Cow
  96 Tests 15 to 18 Days
$1,029.60
Details

More ELISA Kits for Glutathione S-Transferase alpha 2 Interaction Partners

Human Glutathione S-Transferase alpha 2 (GSTa2) interaction partners

  1. the GSTA2 S112T polymorphism is predictive of transplant outcome in patients receiving busulfan in the preparative regimen, at least in association with cyclophosphamide.

  2. Data indicate that steroidogenic factor 1 (SF-1) and glutathione S-transferase A (GSTA) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.

  3. By direct resequencing of the 5'-flanking region, all the exons, and their flanking introns for 107 patients, 29 and 27 variants were identified in GSTA1 and GSTA2, respectively.

  4. Single nucleotide polymorphism in GSTA2 is associated with low-stage non-small cell lung cancer.

  5. Even with typical substrates, the astonishing concentration of glutathione transferase present in hepatocytes, causes an unusual "inverted" kinetics whereby the classical trends of v versus E and v versus S are reversed

  6. it is unlikely that glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 participate in breast cancer susceptibility.

  7. studied the five known allelic variants of human glutathione transferase A2-2 (GST A2-2) (EC 2.5.1.18), abundantly expressed in liver and efficiently catalyzing the bioactivation of azathioprine to release 6-mercaptopurine

  8. The 3D structures of human GSTs A2-2 and A3-3 in complex with Delta(4)-androstene-3-17-dione, were solved.

  9. Polymorphism identified in the proximal promoter of GSTA2 correlate with its expression in the liver and is expected to be of significance for individual risk of cancer or individual response to chemotherapeutic agents.

  10. transmutation into an efficient steroid isomerase

  11. expression of hGSTA1/2 and hGSTA4 steady-state mRNAs in second trimester prenatal livers

  12. expressed at high levels in duodenum and small intestine and expression decreased from proximal to distal small intestine

  13. no association was observed between individual GSTA2 polymorphisms and haplotypes and individual susceptibility to breast cancer.

  14. Overexpression of GSTA2 by transient transfection protected Colo 320HSR cells against both cycle arrest and apoptosis following exposure to HN2.

Glutathione S-Transferase alpha 2 (GSTa2) Antigen Profile

Antigen Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene names and symbols associated with GSTa2

  • glutathione S-transferase alpha 2 (GSTA2) antibody
  • glutathione S-transferase alpha 2 (Gsta2) antibody
  • glutathione S-transferase (GSTA2) antibody
  • glutathione S-transferase, alpha 2 (Yc2) (Gsta2) antibody
  • GST2 antibody
  • Gst2-2 antibody
  • Gsta1 antibody
  • GSTA2-2 antibody
  • Gstc-2 antibody
  • Gstc2 antibody
  • GTA2 antibody
  • GTH2 antibody

Protein level used designations for GSTa2

GST class-alpha member 1 , GST class-alpha member 2 , glutathione S-transferase A1 , glutathione S-transferase A2 , glutathione S-transferase alpha 1 , glutathione S-transferase alpha-1 , glutathione S-transferase alpha-2 , GST HA subunit 2 , GST-gamma , S-(hydroxyalkyl)glutathione lyase A2 , glutathione S-alkyltransferase A2 , glutathione S-aralkyltransferase A2 , glutathione S-aryltransferase A2 , liver GST2 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione-S-transferase, alpha type2 , ligandin , glutathione S-transferase alpha class A2 , glutathione S-transferase GT41A

GENE ID SPECIES
281805 Bos taurus
2939 Homo sapiens
24422 Rattus norvegicus
462769 Pan troglodytes
100379161 Meleagris gallopavo
14858 Mus musculus
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