anti-Glutathione S-Transferase theta 1 (GSTT1) Antibodies

Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Additionally we are shipping GSTT1 Kits (31) and GSTT1 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GSTT1 2952 P30711
GSTT1 25260 Q01579
GSTT1 14871 Q64471
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Top anti-GSTT1 Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-GSTT1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Immunohistochemistry with Lung tissue at an antibody concentration of 5µg/ml using anti-GSTT1 antibody (ARP48490_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, IHC (p), WB IP Image Immunoprecipitation of GSTT1 protein from HepG2 whole cell extracts using 5 μg of GSTT1 antibody, Western blot analysis was performed using GSTT1 antibody, EasyBlot anti-Rabbit IgG  was used as a secondary reagent. WB Image GSTT1 antibody detects GSTT1 protein by Western blot analysis. A. 50 µg mouse spleen lysate/extract 12 % SDS-PAGE GSTT1 antibody , dilution: 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, IHC (p), IP, WB Immunohistochemistry: GSTT1 Antibody [NBP1-32733] - analysis of paraffin-embedded SW480 xenograft, using GSTT1 antibody at 1:500 dilution. Western Blot: GSTT1 Antibody [NBP1-32733] - Sample (30 ug of whole cell lysate)A: Hep G2 10% SDS PAGE, antibody diluted at 1:1000. 100 μL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using GSTT1 antibody. Immunohistochemistry of paraffin-embedded human kidney cancer using GSTT1 antibody at dilution of 1:200 (x400 lens) 100 μL Log in to see 16 Days
$334.02
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Anti-GSTT1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958388 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
$727.83
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Lung Tissue. 100 μg Log in to see 13 to 16 Days
$324.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of GSTT1 using anti-GSTT1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: rat liver tissue lysates, Lane 2: rat lung tissue lysates, Lane 3: mouse liver tissue lysates, Lane 4: mouse lung tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-GSTT1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GSTT1 at approximately 27KD. The expected band size for GSTT1 is at 27KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of GSTT1 (arrow) using rabbit polyclonal GSTT1 Antibody (N-term) (ABIN656825). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GSTT1 gene. Anti-GSTT1 Antibody (N-term)at 1:2000 dilution + human lung lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 27 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated WB Anti-Glutathione S Transferase theta 1 antibody, Western blotting Lane 1: COLO320 Cell Lysate Lane 2: SW620 Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, FACS, WB   0.4 mL Log in to see 8 to 11 Days
$517.00
Details

GSTT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GSTT1 Antibodies

  1. Human Monoclonal GSTT1 Primary Antibody for ELISA, WB - ABIN561166 : Aguilera, Alvarez-Marquez, Gentil, Fernandez-Alonso, Fijo, Saez, Wichmann, Nuñez-Roldan: Anti-glutathione S-transferase T1 antibody-mediated rejection in C4d-positive renal allograft recipients. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal GSTT1 Primary Antibody for ELISA, WB - ABIN561165 : Zenkel, Kruse, Naumann, Schlötzer-Schrehardt: Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma. in Investigative ophthalmology & visual science 2007 (PubMed)

More Antibodies against GSTT1 Interaction Partners

Human Glutathione S-Transferase theta 1 (GSTT1) interaction partners

  1. Homozygous deletion of GSTT1 is associated with slower HIV disease progression.

  2. The null genotype of GSTT1 is a strong predisposing factor for psoriasis in North India.

  3. The patients homozygous for the GSTT1 null alleles showed a 1.5-fold increased risk of Alzheimer's disease.

  4. Results related to GSTT (-) allele and elevation in aspartate aminotransferase (AST) levels should be considered with caution as AST may be elevated in other pathophysiological conditions

  5. MnSODVal allele is a risk factor for systemic lupus erythematosus (SLE), as well as for SLE with neurologic manifestations, while homozygous GSTT1 genotype is a risk factor for SLE with musculoskeletal manifestations.

  6. Higher NO2 exposure was associated with lower forced vital capacity for carriers of the GSTT1 null genotype. Traffic-related air pollution exposures were associated with increased risk of asthma, wheeze and lower lung function in middle-aged adults. The interaction with the GSTT1 genotype suggests that deficient antioxidant mechanisms may play a role in these adverse health effects.

  7. Overall, GSTT1 null genotype was associated with an increased esophageal cancer risk when all studies in Chinese populations pooled into this meta-analysis. In stratified studies with geographical location, significantly increased risk was found in North China (OR = 1.45, 95%CI: 1.11-1.91) and in studies with population-based control (OR = 1.29, 95%CI: 1.07-1.55).

  8. Individuals with ASD (show ARSD Antibodies) (autism spectrum disorder)showed a significant diminished level of reduced glutathione, however, the distribution of GSTT1, GSTM1 (show GSTM1 Antibodies), and GSTP1 (show GSTP1 Antibodies) polymorphisms was not found to be associated with autism in this study population.

  9. GSTM1 (show GSTM1 Antibodies) and GSTT1 gene polymorphisms are closely correlated with the pathogenesis of COPD (show ARCN1 Antibodies).

  10. CML (show BCR Antibodies) patients with carriage of heterozygous and homozygous variant genotypes of GSTP1 (show GSTP1 Antibodies) Ile105Val and GSTT1 null, have a higher risk for development of resistance to IM.

Mouse (Murine) Glutathione S-Transferase theta 1 (GSTT1) interaction partners

  1. minor structural changes in the C-terminal helix of mouse GST T1-1 induce major changes in the substrate-activity profile of the enzyme to favor novel chemical reactions and to suppress other reactions catalyzed by the parental enzyme

  2. The carcinogenic effects of DCM in the mouse are caused by the interaction with DNA of a glutathione (GSH) conjugate that is produced by the class theta glutathione S-transferase T1-1 (GST T1-1).

  3. Gstt1-null mice would be useful as an animal model of humans with the GSTT1-null genotype.

GSTT1 Antigen Profile

Protein Summary

Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Gene names and symbols associated with GSTT1

  • glutathione S-transferase theta-4 (LOC700446) antibody
  • glutathione S-transferase theta-1 (LOC100285763) antibody
  • glutathione S-transferase theta 1a (gstt1a) antibody
  • glutathione S-transferase theta 1 (GSTT1) antibody
  • glutathione S-transferase theta-1 (LOC477556) antibody
  • glutathione S-transferase theta 1 (Gstt1) antibody
  • glutathione S-transferase theta-1 (LOC100153094) antibody
  • glutathione S-transferase theta-1 (LOC100338194) antibody
  • glutathione S-transferase, theta 1 (Gstt1) antibody
  • AI255817 antibody
  • cb870 antibody
  • gstt1 antibody
  • Gstt1-1 antibody
  • GSTYRS antibody
  • LOC100285763 antibody

Protein level used designations for GSTT1

glutathione S-transferase theta 1 , glutathione S-transferase theta-1 , GST class-theta-1 , glutathione transferase T1-1 , GST 5-5 , Glutathione S-transferase 1 (theta) , glutathione S-transferase 5 , GST class-theta , GST-CL1 , theta glutathione-S-transferase

GENE ID SPECIES
700446 Macaca mulatta
100285763 Zea mays
563972 Danio rerio
2952 Homo sapiens
477556 Canis lupus familiaris
517724 Bos taurus
25260 Rattus norvegicus
396322 Gallus gallus
100153094 Sus scrofa
100338194 Oryctolagus cuniculus
14871 Mus musculus
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