anti-Glyoxalase I (GLO1) Antibodies

The enzyme encoded by GLO1 is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Additionally we are shipping Glyoxalase I Kits (28) and Glyoxalase I Proteins (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GLO1 2739 Q04760
GLO1 109801 Q9CPU0
GLO1 294320 Q6P7Q4
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Top anti-Glyoxalase I Antibodies at antibodies-online.com

Showing 10 out of 141 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GLO1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, ICC, IF, IP, SimWes, WB 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Glyoxalase I antibody [N1C3] detects Glyoxalase I protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg A431 whole cell lysate/extract C. 30 μg HeLa whole cell lysate/extract D. 30 μg HepG2 whole cell lysate/extract 12 % SDS-PAGE Glyoxalase I antibody [N1C3] , dilution: 1:1000 ICC/IF Image Glyoxalase I antibody [N1C3] detects Glyoxalase I protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Glyoxalase I protein stained by Glyoxalase I antibody [N1C3] , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Western Blot: Glyoxalase I Antibody [NBP1-31466] - Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE; antibody diluted at 1:1000. 100 μL Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of GLO1 antibody (N-term) (ABIN390591) in HL60 cell line lysates (35 µg/lane). GLO1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GLO1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GLO1 antibody (N-term) in HL60 cell line lysates (35 µg/lane). GLO1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rat Un-conjugated IC, IF, ELISA, WB 100 μg Log in to see 9 to 11 Days
$494.62
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded mouse kidney using GLO1 antibody at dilution of 1:200 (400x lens). 100 μL Log in to see 16 Days
$334.02
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Mouse Rabbit Un-conjugated IP, ELISA, WB 100 μg Log in to see 20 to 21 Days
$218.90
Details

GLO1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Glyoxalase I Antibodies

  1. Human Monoclonal GLO1 Primary Antibody for IC, IF - ABIN2451990 : Hovatta, Tennant, Helton, Marr, Singer, Redwine, Ellison, Schadt, Verma, Lockhart, Barlow: Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice. in Nature 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal GLO1 Primary Antibody for ELISA, ICC - ABIN449661 : Mailankot, Padmanabha, Pasupuleti, Major, Howell, Nagaraj: Glyoxalase I activity and immunoreactivity in the aging human lens. in Biogerontology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal GLO1 Primary Antibody for ELISA, WB - ABIN561054 : Sato, Kwon, Kamisuki, Srivastava, Mao, Kawazoe, Uesugi: Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin. in Journal of the American Chemical Society 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal GLO1 Primary Antibody for ICC, IF - ABIN441467 : Gabriele, Lombardi, Sacco, Napolioni, Altieri, Tirindelli, Gregorj, Bravaccio, Rousseau, Persico: The GLO1 C332 (Ala111) allele confers autism vulnerability: family-based genetic association and functional correlates. in Journal of psychiatric research 2014 (PubMed)

More Antibodies against Glyoxalase I Interaction Partners

Human Glyoxalase I (GLO1) interaction partners

  1. Interdependence of GLO I and PKM2 in the Metabolic shift to escape apoptosis in GLO I-dependent cancer cells.

  2. Induced Glyoxalase 1 expression is a common feature in the pathogenesis of oropharyngeal squamous cell carcinoma

  3. The lowering of glycative stress via modulation of RAGE (show AGER Antibodies)-AGE axis or glyoxalase 1 activity is beneficial for tubular homeostasis and the subsequent prevention and treatment of kidney disease, suggesting the possibility of novel therapeutic approaches which target glycative stress.

  4. Glo-1 responds to dicarbonyl stress to enhance cytoprotection at the transcriptional level through stress-responsive increase of Glo-1 expression.

  5. Glo1, together with Glo2 (show HAGH Antibodies), represents a novel mechanism in prostate cancer progression driven by a PTEN/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway.

  6. Gly82Ser and 2184 A/G RAGE (show AGER Antibodies) polymorphisms were related to the mortality due to the breast cancer and -419 A/C glyoxalase I polymorphism was related to the overall mortality of the patients suggesting their role not only in the risk of breast cancer but also in the outcome of patients with breast cancer.

  7. Reduction of GLO1 activity in atherosclerotic lesions of nondiabetic patients with increased HbA1c is associated with a functional involvement of this protective enzyme in atherogenesis.

  8. Studies suggest that the enhancement of glyoxalase I (GLO-1) is a promising strategy aimed at halting the vicious cycle between chronic kidney disease and increases in glycative stress.

  9. GLO1 on one hand is crucial to maintaining tumor characteristics of malignant cells, and, on the other hand, supports malignant transformation of cells in a hypoxic environment when overexpressed.

  10. GLO1 SNPs are significantly associated with late-onset and drug-resistant epilepsy.

Mouse (Murine) Glyoxalase I (GLO1) interaction partners

  1. Transgenic mice overexpressing Glo1 on both FVB/NJ (FVB) or C57BL/6J (B6) backgrounds showed increased voluntary EtOH consumption compared to their wild-type littermates. Transgenic Glo1 knockdown mice on a B6 background showed decreased voluntary EtOH consumption. Genetic manipulations of Glo1 had no effect on sucrose, saccharin or water consumption.

  2. the Glo1-methylglyoxal pathway integrates maternal and neural precursor cell metabolism to regulate neural development.

  3. These data indicate that Glo1 knockout reduces anxiety-like behavior, but increases depression-like behavior.

  4. Alternative detoxification of methylglyoxal in GLO1(-/-) is achieved by increased catalytic efficiency of aldose reductase (show AKR1B1 Antibodies) toward hemithioacetal (product of glutathione and methylglyoxal ), which is most likely caused by S-nitrosylation of aldose reductase (show AKR1B1 Antibodies).

  5. Glo1 knockdown does not have major short term effects on the energy expenditure or the formation of atherosclerotic plaques.

  6. Crystal structure of the mouse Glo1-inhibitor complex was determined at 2.3 A resolution.

  7. Study demonstrates that GLO1 is a novel metabolic oncogene (show RAB1A Antibodies) of the 6p21 amplicon, which promotes tumor growth and aberrant transcriptional signals via regulating cellular metabolic activities for energy production.

  8. the balance between methylglyoxal and age-dependent GLO1 downregulation contributes to delayed wound healing in old mice

  9. The difference in glyoxalase-1 mRNA was observed with Fkbp5 (show FKBP5 Antibodies)-/- mice expressing 2-fold more glyoxylase-1 protein.

  10. pharmacological inhibition of GLO1 reduced anxiety, suggesting that GLO1 is a possible target for the treatment of anxiety disorders.

Arabidopsis thaliana Glyoxalase I (GLO1) interaction partners

Glyoxalase I (GLO1) Antigen Profile

Protein Summary

The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.

Gene names and symbols associated with anti-Glyoxalase I (GLO1) Antibodies

  • glyoxalase I (GLO1) antibody
  • glyoxalase 1 (Glo1) antibody
  • glyoxalase 1 (glo1) antibody
  • glyoxalase 1 L homeolog (glo1.L) antibody
  • glyoxalase 1 S homeolog (glo1.S) antibody
  • lactoylglutathione lyase (GST3) antibody
  • glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein (GLX1) antibody
  • lactoylglutathione lyase (STY1687) antibody
  • lactoylglutathione lyase (GLO1) antibody
  • glyoxalase I (Bcen_2094) antibody
  • glyoxalase I (gloA) antibody
  • glyoxalase I (Glo1) antibody
  • 0610009E22Rik antibody
  • 1110008E19Rik antibody
  • 2510049H23Rik antibody
  • ATGLX1 antibody
  • AW550643 antibody
  • cb554 antibody
  • F12F1.32 antibody
  • F12F1_32 antibody
  • Glo-1 antibody
  • Glo-1r antibody
  • Glo-1s antibody
  • GLO1 antibody
  • Glo1-r antibody
  • Glo1-s antibody
  • glod1 antibody
  • GLY1 antibody
  • glyi antibody
  • GLYOXALASE I antibody
  • glyoxalase I homolog antibody
  • Qglo antibody
  • trypanothione-dependent glyoxalase I antibody
  • wu:fb82g09 antibody
  • zgc:66035 antibody

Protein level used designations for anti-Glyoxalase I (GLO1) Antibodies

S-D-lactoylglutathione methylglyoxal lyase , aldoketomutase , glx I , glyoxalase domain containing 1 , ketone-aldehyde mutase , lactoyl glutathione lyase , lactoylglutathione lyase , methylglyoxalase , glyoxalase 1 complex , glyoxalase 1 regulatory , glyoxalase 1 structural , glyoxalase I , hypothetical protein , trypanothione-dependent glyoxalase I , glyoxylase 1

GENE ID SPECIES
2739 Homo sapiens
109801 Mus musculus
368213 Danio rerio
421428 Gallus gallus
446359 Xenopus laevis
447401 Xenopus laevis
474894 Canis lupus familiaris
540335 Bos taurus
547925 Glycine max
594942 Xenopus (Silurana) tropicalis
719518 Macaca mulatta
748215 Pan troglodytes
837731 Arabidopsis thaliana
1248061 Salmonella enterica subsp. enterica serovar Typhi str. CT18
3639312 Candida albicans SC5314
4091104 Burkholderia cenocepacia AU 1054
4850985 Scheffersomyces stipitis CBS 6054
5073200 Leishmania infantum JPCM5
6924240 Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91
6949741 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
100156085 Sus scrofa
294320 Rattus norvegicus
100726491 Cavia porcellus
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