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The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Additionally we are shipping GOLGA5 Antibodies (91) and many more products for this protein.
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Mdm2 (show MDM2 Proteins) overexpression and Cdc25C (show CDC25C Proteins) downregulation delay cell cycle progression through the G2/M phase.
Xanthatin functions as a DNA-damaging agent in non-small cell lung carcinomas by activating Chk1 (show CHEK1 Proteins)-mediated DDR (show DDR1 Proteins) and lysosome-mediated degradation of Cdc25C (show CDC25C Proteins).
Myelodysplastic syndrome -related P95 (show NBN Proteins) point mutants of SRSF2 (show SRSF2 Proteins) lead to alternative splicing of CDC25C (show CDC25C Proteins) in a manner that is not dependent on the DNA damage response.
The aim of this review is to shed light on the role of four different phosphatases (PTEN, PP2A (show PPP2R4 Proteins), CDC25 (show RASGRF1 Proteins) and DUSP1 (show DUSP1 Proteins)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.
Data show that TRIB2 (show TRIB2 Proteins)-mediated degradation of CDC25C (show CDC25C Proteins) is associated with lysine-48-linked CDC25C (show CDC25C Proteins) polyubiquitination driven by the TRIB2 (show TRIB2 Proteins) kinase-like domain.
the biology of the activation/deactivation of CDC25 (show RASGRF1 Proteins) by kinases/phosphatases to maintain the level of CDK (show CDK4 Proteins)-cyclin (show PCNA Proteins) activities and thus the genomic stability
the knockdown of CDC25C (show CDC25C Proteins) can reduce both the radiotherapy sensitivity and the proliferation activity of EC9706 cells.
results identify CDC25C (show CDC25C Proteins) as a downstream target of the mutated tyrosine kinase (show TXK Proteins) FLT3 (show FLT3 Proteins)-ITD affecting cell-cycle regulation in a model of AML (show RUNX1 Proteins)
Suggest that the p53-p21-DREAM-CDE/CHR pathway regulates p53-dependent repression of Survivin, CDC25C, and PLK1 in HCT116 cells.
Data indicate that nine compounds were identified with Ki values for CDC25A, -B and -C ranging from 0.01 to 4.4 muM.
Golga5 is not required for mouse embryonic development, postnatal survival, or fertility.
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues\; the chimeric sequences have been designated RET-II and PTC5.
Golgin subfamily A member 5
, RET-fused gene 5 protein
, cell proliferation-inducing gene 31 protein
, golgi autoantigen, golgin subfamily a, 5
, golgi integral membrane protein 5
, golgin A5
, golgin subfamily A member 5-like
, Golgin subfamily A member 5-like
, protein Sumiko
, golgin subfamily A member 5