Grancalcin, EF-Hand Calcium Binding Protein (GCA) ELISA Kits

GCA product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. Additionally we are shipping Grancalcin Antibodies (26) and Grancalcin Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GCA 227960 Q8VC88
Anti-Rat GCA GCA 295647  
GCA 25801 P28676
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Top Grancalcin ELISA Kits at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human < 0.1 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Mouse < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days
$838.60
Details

More ELISA Kits for Grancalcin Interaction Partners

Mouse (Murine) Grancalcin, EF-Hand Calcium Binding Protein (GCA) interaction partners

  1. Homozygous Gca mutants appeared healthy and reproduced normally. Leukocyte recruitment into the peritoneal cavity upon induction of inflammation was not significantly affected by the absence of grancalcin.

  2. findings suggest that grancalcin plays a key role in leukocyte-specific functions that are responsible for host defense

  3. Adhesion to fibronectin of grancalcin-deficient neutrophils was decreased by 60% compared to control cells.

Human Grancalcin, EF-Hand Calcium Binding Protein (GCA) interaction partners

  1. Results indicate that heterodimerization of GCA and TLR9 is important for TLR9-mediated downstream signaling and might serve to fine tune processes against viral infection.

  2. GCA interacts with SRI in vivo and in vitro.

  3. The reported type 1 diabetes association is from a linkage disequilibrium region including three candidate genes, FAP, IFIH1 and GCA.

  4. IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis.

  5. IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients

Grancalcin (GCA) Antigen Profile

Antigen Summary

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction\; with magnesium alone, it partitions with the granule fraction\; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Gene names and symbols associated with GCA

  • zgc:92027 (zgc:92027) antibody
  • grancalcin (GCA) antibody
  • Grancalcin (gran) antibody
  • grancalcin (LOC100280890) antibody
  • grancalcin (Gca) antibody
  • 5133401E04Rik antibody
  • AI573844 antibody
  • GCL antibody
  • Grancalcin antibody

Protein level used designations for GCA

grancalcin , Grancalcin , grancalcin, EF-hand calcium-binding protein , grancalcin, penta-EF-hand protein

GENE ID SPECIES
449543 Danio rerio
100174456 Pongo abelii
100195546 Salmo salar
100280890 Zea mays
227960 Mus musculus
295647 Rattus norvegicus
25801 Homo sapiens
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