anti-Heat Shock 27kDa Protein 2 (HSPB2) Antibodies

Zebrafish Heat Shock 27kDa Protein 2 (HSPB2) interaction partners

1. hspb2 is expressed during development.

Human Heat Shock 27kDa Protein 2 (HSPB2) interaction partners

1. in differentiating myoblasts, nuclear HSPB2 compartments sequester lamin A (show LMNA Antibodies).

2. HSPB2 competes with HSPB8 (show HSPB8 Antibodies) for binding to BAG3 (show BAG3 Antibodies). In contrast, HSPB3 (show HSPB3 Antibodies) negatively regulates HSPB2 association with BAG3 (show BAG3 Antibodies).

3. Three of the differentially expressed heat-schock proteins, HSP90A (show HSP90AA1 Antibodies), HSPB1 (show HSPB1 Antibodies), and HSPB2, are up-regulated in giant cell tumor of bone patients.

4. HspB2 has roles in maintaining ATP levels and as well as chaperone-dependent functions for metabolic homeostasis

5. Results suggest a limited function of alphaB-crystallin (show CRYAB Antibodies) and HSP27 (show HSPB1 Antibodies) in preventing abnormal tau protein deposition in glial cells and neurons; in addition, the expression of alphaB-crystallin (show CRYAB Antibodies) phosphorylated at Ser59 may act as a protective factor in glial cells.

6. These findings provide novel insights into the role of p53 (show TP53 Antibodies) as a regulator of bidirectional gene pair HspB2/alpha B-crystallin (show CRYAB Antibodies)-mediated ROS (show ROS1 Antibodies) and the Warburg effect

7. Study shows that HspB2 oligomers exchange subunits.

8. Reveal a novel function of HspB2 as an anti-apoptotic protein that negatively regulates apical caspase 3 (show CASP3 Antibodies)/8 activation in the extrinsic apoptotic pathway.

9. Hsp27 (show HSPB1 Antibodies), but not the classic Hsp60 (show HSPD1 Antibodies) and Hsp70 (show HSP70 Antibodies), may be associated with the development bronchiolitis obliterans syndrome.

10. Sodium salicylate can induce the expression of HSP27 (show HSPB1 Antibodies) in human lens epithelial cells.

Mouse (Murine) Heat Shock 27kDa Protein 2 (HSPB2) interaction partners

1. We found significantly slower retrograde transport of mitochondria in Ser135Phe, Pro39Leu and Arg140Gly mutant Hsp27 (show HSPB1 Antibodies) expressing motor neurons than in wild type Hsp27 (show HSPB1 Antibodies) neurons, although anterograde movement velocities remained normal.

2. HSP27 (show HSPB1 Antibodies) expression is upregulated in lung fibroblasts during pulmonary fibrosis, and subsequently, HSP27 (show HSPB1 Antibodies) modulates lung fibroblast differentiation through the Smad3 (show SMAD3 Antibodies) and ERK (show EPHB2 Antibodies) pathways.

3. phosphorylated Hsp27 (show HSPB1 Antibodies) stimulates autophagy and lipid droplet clearance and interacts with STAT3 (show STAT3 Antibodies).

4. The phosphorylation of S82 of the heat shock protein 27 kDa (HSP27 (show HSPB1 Antibodies)), was especially abundant and consistently upregulated in tissues with delays in freezing as short as 2 minutes.

5. HspB2 has roles in maintaining ATP levels and as well as chaperone-dependent functions for metabolic homeostasis

6. Hsp27 (show HSPB1 Antibodies) binding to the 3'UTR (show UTS2R Antibodies) of Bim (show BCL2L11 Antibodies) mRNA prevents neuronal death during oxidative stress-induced (show SQSTM1 Antibodies) injury.

7. These findings indicate that in mice HSP27 (show HSPB1 Antibodies) and HSP70 (show HSP70 Antibodies) play a key role in the induction of cell-mediated immunity to carcinogenic polyaromatic hydrocarbons

8. The myocardium releases HSP27 (show HSPB1 Antibodies) after global ischemia: the proinflammatory effect of extracellular HSP27 (show HSPB1 Antibodies) through TLR2 and TLR4 (show TLR4 Antibodies).

9. protective role for endothelial S1P1R against ischemic acute kidney injury most likely by regulating endothelial barrier integrity and endothelial HSP27 (show HSPB1 Antibodies) expression

10. findings reveal a novel role for HSP27 (show HSPB1 Antibodies) in the maintenance of BBB (show ALMS1 Antibodies) integrity.