anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) Antibodies

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Additionally we are shipping HSP90AA2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID
HSP90AA2 3324
HSP90AA2  
HSP90AA2  
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Top anti-HSP90AA2 Antibodies at antibodies-online.com

Showing 10 out of 236 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC, ELISA, WB Hsp90alpha (K41009) Mouse Colon Cancer 1 IN 5,000, Amplifier. Total Rat Tissue Hsp90alpha WB 1 in 1000. 100 μg Log in to see 3 to 4 Days
$399.30
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Figure 1 shows a Western blot of mouse HSP84 and HSP86 using ABIN266969 and ABIN266968, respectively. Western Blot: HSP90 alpha Antibody [ABIN266969] - Proteins were transferred to a PVDF membrane and blocked with 5% BSA/TBST for at least 1 hour. The membrane was probed with a HSP86 polyclonal antibody at a dilution of 1:1000 overnight at 4C on a rocking platform, washed in TBS-0.1%Tween 20, and probed with a goat anti-rabbit IgG HRP secondary antibody at a dilution of 1:20,000 for at least 1 hour. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Mouse Un-conjugated ICC, IF, IP, IHC, ELISA, WB Western Blotting Hsp90lpha RatTissue 10ug 1 in 1000 copy. 50 μg Log in to see 3 to 4 Days
$217.80
Details
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of HSP90 alpha staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HSP90 alpha staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry: HSP90 alpha Antibody [NBP1-77682] - Hsp90A Antibody [NBP1-77682] - Analysis of Hsp901a in human kidney carcinoma using DAB with hematoxylin counterstain. Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody [NBP1-77682] - Hsp90A Antibody [NBP1-77682] - HSP90-1A antibody was tested in MCF-7 cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red). 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody (SY14-06)  - Staining Hsp90 alpha in Ags cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Immunocytochemistry/Immunofluorescence: HSP90 alpha Antibody (SY14-06)  - Staining Hsp90 alpha in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 100 μL Log in to see 34 Days
$373.75
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse testis Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes Blocking buffer (normal goat serum) at 37°C for 30min Antibody incubation with HSP90 alpha Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, DAB staining. 100 μL Log in to see 14 to 21 Days
$306.90
Details
Human Mouse Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (p), WB Immunohistochemistry-Paraffin: HSP90 alpha Antibody (5G5) [NBP2-22208] - Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using Hsp90A mouse mAb with DAB staining. Flow Cytometry: HSP90 alpha Antibody (5G5) [NBP2-22208] - Flow cytometric analysis of HeLa cells using Hsp90A mouse mAb (green) and negative control (red). 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Mouse HRP IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3 to 4 Days
$437.80
Details
Human Mouse FITC IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Log in to see 3 to 4 Days
$442.20
Details

HSP90AA2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-HSP90AA2 Antibodies

  1. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN266969 : Peterson, Moran, Conley, Bird: Zonal expression of endothelial nitric oxide synthase in sheep and rhesus adrenal cortex. in Endocrinology 2001 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal HSP90AA2 Primary Antibody for IHC, ELISA - ABIN361714 : Arlander, Eapen, Vroman, McDonald, Toft, Karnitz: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. in The Journal of biological chemistry 2003 (PubMed)
    Show all 16 Pubmed References

  3. Human Monoclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN361663 : Minami, Kawasaki, Miyata, Suzuki, Yahara: Analysis of native forms and isoform compositions of the mouse 90-kDa heat shock protein, HSP90. in The Journal of biological chemistry 1991 (PubMed)
    Show all 15 Pubmed References

  4. Human Polyclonal HSP90AA2 Primary Antibody for IF (p), IHC (p) - ABIN1714199 : Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost. in Developmental and comparative immunology 2013 (PubMed)

  5. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN4320479 : Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. in Journal of leukocyte biology 2017 (PubMed)

More Antibodies against HSP90AA2 Interaction Partners

Zebrafish Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) interaction partners

  1. The transcriptional up-regulation of unc45b, hsp90aa1.1 and smyd1b is specific to zebrafish mutants with myosin folding defects, and is not triggered in other zebrafish myopathy models

  2. Data indicate that heat shock protein 90alpha (Hsp90alpha1) function in myosin thick filament organization is potentially regulated by post-translational modification (PTM) involving phosphorylation and acetylation.

  3. The chaperone proteins Ahsa1 (show AHSA1 Antibodies) and Hsp90 (show HSP90 Antibodies) promote severe craniofacial phenotypes in zebrafish model of HDR (show GATA3 Antibodies) syndrome.

  4. Perturbation of the HSP70 (show HSPA1A Antibodies)-HSP90 (show HSP90 Antibodies) heat-shock protein axis stimulates degradation of endothelial VEGFR2 (show KDR Antibodies).

  5. studies indicate that the hsp90alpha1 mutant phenotype is not simply due to disruption of myosin folding and assembly, suggesting that Hsp90alpha1 may play a role in the assembly and organization of other sarcomeric structures

  6. Mild perturbation of Hsp90 (show HSP90 Antibodies) function at critical developmental stages may underpin the variable penetrance and expressivity of many developmental anomalies where the interaction between genotype and environment plays a major role.

  7. Steif/Unc-45b (show UNC45B Antibodies) interacts with the chaperone Hsp90a (show HSP90AA1 Antibodies) in vitro. The two genes are co-expressed in the skeletal musculature.

  8. Embryonic heat shock reveals latent hsp90 (show HSP90 Antibodies) translation in zebrafish.

  9. Loss of Hsp90a (show HSP90AA1 Antibodies) function leads to the downregulation of genes encoding sarcomeric proteins and upregulation of hsp90a (show HSP90AA1 Antibodies) and several other genes encoding proteins that may act with Hsp90a (show HSP90AA1 Antibodies) during sarcomere assembly.

  10. In response to stress or damage to the myofiber, Unc45b and Hsp90a dissociate from the Z line and transiently associate with myosin.

Human Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) interaction partners

  1. Knocking out Hsp90beta (show HSP90AB1 Antibodies) leads to tumour cell death. Extracellular supplementation with recombinant Hsp90alpha, but not Hsp90beta (show HSP90AB1 Antibodies), protein recovers tumourigenicity of the Hsp90alpha-knockout cells. Sequential mutagenesis identifies two evolutionarily conserved lysine residues, lys (show LYZ Antibodies)-270 and lys (show LYZ Antibodies)-277, in the Hsp90alpha subfamily that determine the extracellular Hsp90alpha function.

  2. We revealed that Hsp90A (show HSP90AA1 Antibodies) and Hsp90B (show HSP90AB1 Antibodies) are partly colocalized with heparan sulfate proteoglycans (HSPGs) on the cell surface and that this colocalization was sensitive to heparin.

  3. Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways

  4. Studied the serum prolactin (show PRL Antibodies), cortisol, and ACTH (show POMC Antibodies) stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects.

  5. These results indicate that cytoplasmic HSP90alpha may serve as a biomarker for perineural invasion in pancreatic cancer

  6. Increased expression of nucleated RBC (show CACNA1C Antibodies), HSP90alpha and corresponding decreased expression of HO-2 (show HMOX2 Antibodies) in such hypoxic condition may play a protective role; to prevent cord blood RBC (show CACNA1C Antibodies) against stress induced damage during preeclampsia.

  7. STAT5b (show STAT5B Antibodies) pathway regulates Hsp90alpha expression under hypoxic conditions

  8. HSP90alpha was an IMH-2 epitope-associated protein. Tumor HSP90alpha overexpression was correlated with the metastasis and poor prognosis of colorectal cancer patients.

  9. extracellular HSP90alpha transactivates EGFR/ErbB1 (show EGFR Antibodies) through TLR4 (show TLR4 Antibodies) and a PKCdelta (show PKCd Antibodies)/c-Src (show SRC Antibodies) pathway, which induces ATP release and cytosolic Ca(2 (show CA2 Antibodies)+) increase and finally favors glioblastoma cell migration.

  10. High gene expression of Hsp90 alpha (show HSP90AA1 Antibodies) is associated with leukemia.

HSP90AA2 Antigen Profile

Protein Summary

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

Gene names and symbols associated with HSP90AA2

  • heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P) antibody
  • HSP90ALPHA antibody
  • HSPCA antibody
  • HSPCAL3 antibody
GENE ID SPECIES
3324 Homo sapiens
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