anti-Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) Antibodies

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Additionally we are shipping HSP90AA2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID
HSP90AA2 3324
HSP90AA2  
HSP90AA2  
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Top anti-HSP90AA2 Antibodies at antibodies-online.com

Showing 10 out of 169 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Mouse Un-conjugated ICC, IF, IP, IHC, ELISA, WB Western Blotting Hsp90lpha RatTissue 10ug 1 in 1000 copy. 50 μg 3 to 4 Days
$257.40
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot (WB) analysis of HSP90α (P717) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:NIH-3T3 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:L02 whole cell lysate(40ug) 100 μL 3 to 4 Days
$325.00
Details
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of HSP90 alpha staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HSP90 alpha staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
$487.50
Details
Human Mouse FITC IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$522.60
Details
Human Mouse APC IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$531.70
Details
Human Mouse PerCP IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$531.70
Details
Human Mouse Atto 680 IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$533.00
Details
Human Mouse Atto 565 IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$533.00
Details
Human Mouse Atto 633 IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$533.00
Details
Human Mouse Atto 488 IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Western Blot analysis of Rat Lysates showing detection of Hsp90 alpha protein using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg 3 to 4 Days
$533.00
Details

Top referenced anti-HSP90AA2 Antibodies

  1. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN266969 : Peterson, Moran, Conley, Bird: Zonal expression of endothelial nitric oxide synthase in sheep and rhesus adrenal cortex. in Endocrinology 2001 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal HSP90AA2 Primary Antibody for IF, IHC - ABIN6711796 : Wang, Zhao, Qi, Gu, Rong, Mu, Zou, Tao, You, Guo: Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP. in Journal of cellular biochemistry 2011 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN361663 : Arlander, Eapen, Vroman, McDonald, Toft, Karnitz: Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. in The Journal of biological chemistry 2003 (PubMed)
    Show all 15 Pubmed References

  4. Human Polyclonal HSP90AA2 Primary Antibody for IF (p), IHC (p) - ABIN1714199 : Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost. in Developmental and comparative immunology 2013 (PubMed)

  5. Human Polyclonal HSP90AA2 Primary Antibody for ICC, IF - ABIN4320479 : Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. in Journal of leukocyte biology 2017 (PubMed)

More Antibodies against HSP90AA2 Interaction Partners

Human Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2) interaction partners

  1. Study suggests that HSP90AA2 gene polymorphisms are associated with SLE susceptibility in Chinese population.

  2. The Hsp90alpha binds human recombinant p23 about three times stronger than Hsp90beta but with significantly smaller exothermic enthalpy as determined by isothermal titration calorimetry of direct binding between the purified proteins.

  3. Knocking out Hsp90beta leads to tumour cell death. Extracellular supplementation with recombinant Hsp90alpha, but not Hsp90beta, protein recovers tumourigenicity of the Hsp90alpha-knockout cells. Sequential mutagenesis identifies two evolutionarily conserved lysine residues, lys-270 and lys-277, in the Hsp90alpha subfamily that determine the extracellular Hsp90alpha function.

  4. We revealed that Hsp90A and Hsp90B are partly colocalized with heparan sulfate proteoglycans (HSPGs) on the cell surface and that this colocalization was sensitive to heparin.

  5. Heat shock protein 90 stimulates rat mesenchymal stem cell migration via PI3K/Akt and ERK1/2 pathways

  6. Studied the serum prolactin, cortisol, and ACTH stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects.

  7. These results indicate that cytoplasmic HSP90alpha may serve as a biomarker for perineural invasion in pancreatic cancer

  8. Increased expression of nucleated RBC, HSP90alpha and corresponding decreased expression of HO-2 in such hypoxic condition may play a protective role; to prevent cord blood RBC against stress induced damage during preeclampsia.

  9. Heat shock protein 90alpha is a substrate and chaperone of DNA-PK necessary for the apoptotic response.

  10. STAT5b pathway regulates Hsp90alpha expression under hypoxic conditions

  11. HSP90alpha was an IMH-2 epitope-associated protein. Tumor HSP90alpha overexpression was correlated with the metastasis and poor prognosis of colorectal cancer patients.

  12. extracellular HSP90alpha transactivates EGFR/ErbB1 through TLR4 and a PKCdelta/c-Src pathway, which induces ATP release and cytosolic Ca(2+) increase and finally favors glioblastoma cell migration.

  13. High gene expression of Hsp90 alpha is associated with leukemia.

  14. extracellular Hsp90alpha promotes angiogenesis in an MMP-2-dependent manner.

  15. that Hsp90alpha can be secreted by activated endothelial cells and is a positive regulator of angiogenesis, suggesting the potential application of Hsp90alpha as a stimulator for wound repair.

  16. Promoter activity analysis revealed that hepatitis B virus X protein is directly involved in the c-Myc-mediated transcriptional activation of HSP90alpha.

  17. The hsp90 alpha isoform, but not hsp90 beta, is expressed extracellularly where it interacts with the matrix metalloproteinase 2 (MMP2). Inhibition of extracellular hsp90 alpha decreases both MMP2 activity and invasiveness.

  18. The reciprocal interactions of HSP90 and NF-kappa B activities are likely to constitute a regulatory loop, able to influence cell survival and response to stressful agents

  19. These findings provide a rationale for targeting HSP90alpha protein as a therapeutic candidate for glioma.

  20. C-terminal tail and determinants in the alphaE-helix of the catalytic domain allows the chaperones Hsp90 and Cdc37 to bind newly synthesized PKC beta II, a required event in the processing of PKC by phosphorylation

HSP90AA2 Antigen Profile

Protein Summary

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

Gene names and symbols associated with HSP90AA2

  • heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P) antibody
  • HSP90ALPHA antibody
  • HSPCA antibody
  • HSPCAL3 antibody
GENE ID SPECIES
3324 Homo sapiens
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