Hermansky-Pudlak Syndrome 5 Proteins (HPS5)

HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Additionally we are shipping HPS5 Antibodies (26) and HPS5 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HPS5 11234 Q9UPZ3
Rat HPS5 HPS5 308598  
HPS5 246694 P59438
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top HPS5 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

HPS5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Hermansky-Pudlak Syndrome 5 (HPS5) Interaction Partners

Human Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. HPS5 mutation is associated with high hypopigmentation in Hermansky-Pudlak syndrome.

  2. We report a 92-year-old man with HPS 5 who, to our knowledge, is the oldest patient with HPS (show HPS1 Proteins) documented in the literature.

  3. Seven mutations (six previously unreported) were described in the HPS1 (show HPS1 Proteins), HPS4 (show HPS4 Proteins), and HPS5 genes among Hermansky-Pudlak Syndrome patients of Mexican, Uruguayan, Honduran, Cuban, Venezuelan, and Salvadoran ancestries.

  4. Component of BLOC-2 (show HPS6 Proteins). Results suggest a common biological basis underlying the pathogenesis of HPS-3 (show HPS3 Proteins), -5 and -6 disease.

  5. LAMP-3 (show CD63 Proteins) distribution was restricted to the perinuclear region in HPS-5 fibroblasts, instead of extending to the periphery

  6. Tyrosinase (show TYR Proteins) and TYRP1 (show TYRP1 Proteins) are mistrafficked, however, and fail to be efficiently delivered to melanosomes of HPS-5 melanocytes

Zebrafish Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. The snw/hps5I76N mutant provides a valuable resource for structure-function analyses of Hps5 and enables further elucidation of the molecular and cellular mechanisms underlying HPS (show AP3B1 Proteins).

Mouse (Murine) Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. Nonsense Mutation in HPS5 gene is associated with hypopigmentation in colitis mice.

  2. Effects of the ru2(d) allele on pheomelanin synthesis were investigated.

  3. These results suggest that the ru2(d) allele suppresses the differentiation of melanocytes through the inhibition of eumelanin synthesis, but stimulates pheomelanin synthesis in melanocytes.

  4. These results suggest that the ru2(d) allele inhibits melanocyte differentiation, and that its impaired differentiation is rescued by excess tyrosine.

HPS5 Protein Profile

Protein Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

Gene names and symbols associated with HPS5

  • HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 (HPS5)
  • HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 (Hps5)
  • Hermansky-Pudlak syndrome 5 (hps5)
  • Aa2-028 protein
  • Ab1-018 protein
  • AI646796 protein
  • AIBP63 protein
  • AL022647 protein
  • C85120 protein
  • haze protein
  • hz protein
  • maroon protein
  • mr protein
  • ru-2 protein
  • ru2 protein
  • zgc:162420 protein

Protein level used designations for HPS5

Hermansky-Pudlak syndrome 5 protein , alpha integrin binding protein 63 , alpha-integrin-binding protein 63 , ruby-eye protein 2 homolog , Hermansky-Pudlak syndrome 5 , Hermansky-Pudlak syndrome 5 protein homolog , ruby eye 2 , ruby-eye protein 2

GENE ID SPECIES
11234 Homo sapiens
308598 Rattus norvegicus
423079 Gallus gallus
510165 Bos taurus
100036709 Xenopus (Silurana) tropicalis
100037388 Danio rerio
100049701 Sus scrofa
100446504 Pongo abelii
100549976 Meleagris gallopavo
100616949 Monodelphis domestica
246694 Mus musculus
100716300 Cavia porcellus
101119945 Ovis aries
Selected quality suppliers for HPS5 Proteins (HPS5)
Did you look for something else?