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anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Antibodies

HNRNPA1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

list all antibodies Gene Name GeneID UniProt
Anti-Human HNRNPA1 HNRNPA1 3178 P09651
Anti-Mouse HNRNPA1 HNRNPA1 15382 P49312
Anti-Rat HNRNPA1 HNRNPA1 29578 P04256
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Top anti-Heterogeneous Nuclear Ribonucleoprotein A1 Antibodies at antibodies-online.com

Showing 10 out of 136 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Mouse Un-conjugated ICC, IF, IP, MA, ELISA, WB Western Blot: hnRNP A1 Antibody (4B10) [ABIN152096] - Whole cell protein from HeLa (lane 1), A431 (lane 2), Hek293 (lane 3) and MCF7 (lane 4) were separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 0.5 mg/ml anti-hnRNP in 1% milk. Precision Plus Protein All Blue molecular weight markers (BioRad) were detected with 1 ug/ml Anti-Blue Marker antibody (NBP2-33376). Both antibodies were detected with an anti-mouse HRP secondary antibody using chemiluminescence. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HNRPA1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate HNRNPA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit Anti-HNRPA1 Antibody Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HNRPA1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate HNRNPA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells ARP40384 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$229.00
Details
Mouse Mouse Un-conjugated ICC, FACS, IF, IHC (p), IP, ELISA, WB Western blot for anti-hnRNP-A1 on HeLa cell extracts 50 μL Log in to see 7 to 8 Days
$455.57
Details
Chicken Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of hnRNP A1 staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of hnRNP A1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image hnRNP A1 antibody detects HNRNPA1 protein by Western blot analysis. A. 30 µg PC-12 whole cell lysate/extract 12 % SDS-PAGE hnRNP A1 antibody , dilution: 1:1000 WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB HnRNP A1 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- HnRNP A1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). HnRNP A1 was detected in paraffin-embedded sections of human placenta tissues using rabbit anti- HnRNP A1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from 293/Jurkat/COLO205 cells, using hnRNP A1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using hnRNP A1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: hnRNP A1 Antibody [NBP1-32161] - Paraffin-embedded Ca922 xenograft, using antibody at 1:100 dilution. Western Blot: hnRNP A1 Antibody [NBP1-32161] - Sample(30 ug of whole cell lysate) A:H1299 B:HeLa S3 12% SDS PAGE, antibody diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB Anti-HNRNPA1 / HnRNP A1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN959331 concentration 5 ug/ml. 50 μL Log in to see 7 to 9 Days
$484.00
Details

Top referenced anti-Heterogeneous Nuclear Ribonucleoprotein A1 Antibodies

  1. Cow (Bovine) Monoclonal HNRNPA1 Primary Antibody for ICC, IF - ABIN152096 : Izaurralde, Jarmolowski, Beisel, Mattaj, Dreyfuss, Fischer: A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. in The Journal of cell biology 1997 (PubMed)
    Show all 18 Pubmed References

  2. Mouse (Murine) Monoclonal HNRNPA1 Primary Antibody for ICC, FACS - ABIN108609 : Burd, Dreyfuss: RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. in The EMBO journal 1994 (PubMed)
    Show all 10 Pubmed References

  3. Mouse (Murine) Monoclonal HNRNPA1 Primary Antibody for ICC, FACS - ABIN108610 : Matunis, Xing, Dreyfuss: The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. in Nucleic acids research 1994 (PubMed)
    Show all 10 Pubmed References

  4. Cow (Bovine) Polyclonal HNRNPA1 Primary Antibody for IHC, WB - ABIN2778789 : Xia: Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal HNRNPA1 Primary Antibody for ICC, IF - ABIN108583 : Piñol-Roma, Choi, Matunis, Dreyfuss: Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins. in Genes & development 1988 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal HNRNPA1 Primary Antibody for ICC, IF - ABIN108584 : Guil, Cáceres: The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. in Nature structural & molecular biology 2007 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Heterogeneous Nuclear Ribonucleoprotein A1 Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. Results suggest that telomeric repeat-containing RNA (TERRA (show DMRT2 Antibodies)) regulates binding of heterogeneous nuclear ribonucleoprotein A1 to the telomere in a region surrounding the telomere, leading to a deeper understanding of the mechanism of TERRA (show DMRT2 Antibodies) function.

  2. mutation in HNRNPA1 located in the nuclear localization signal domain of hnRNPA1, enhances the recruitment of mutant hnRNPA1 into stress granules, indicating that an altered nuclear localization signal activity plays an essential role in amyotrophic lateral sclerosis pathogenesis.

  3. Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution have been described.

  4. study showed that UVB induces alternative splicing of hdm2 by increasing the expression and the binding of hnRNP A1 to hdm2 full-length mRNA

  5. The authors show by NMR spectroscopy that both RNA recognition motifs of hnRNP A1 can bind simultaneously to a single bipartite motif of the human intronic splicing silencer ISS-N1, which controls survival of motor neuron exon 7 splicing.

  6. current knowledge of the involvement of hnRNPA1 in cancer, including its roles in regulating cell proliferation, invasiveness, metabolism, adaptation to stress and immortalization.

  7. Case Report: inflammatory myofibroblastic tumor (IMT) of the urinary bladder with a novel HNRNPA1-ALK fusion.

  8. EGF (show EGF Antibodies) signaling upregulates an E3 ubiquitin (Ub) ligase adaptor, SPRY domain-containing SOCS box protein 1 (SPSB1 (show SPSB1 Antibodies)), which recruits Elongin B (show TCEB2 Antibodies)/C-Cullin complexes to conjugate lysine 29-linked poly Ubiquitin chains onto hnRNP A1.

  9. hnRNP A1 directly binds to the 5' untranslated region of the RON (show MST1R Antibodies) mRNA and activates its translation through G-quadruplex RNA secondary structures

  10. We demonstrate that the wild-type sequence harbors an hnRNP A1 and hnRNP A2/B1 (show HNRNPA2B1 Antibodies)-binding exonic splicing silencer (ESS) overlapping the 5'splice site (5'ss) that prevents pseudoexon inclusion.we demonstrate that splice switching oligonucleotide (SSO) mediated blocking of the pseudoexon 3'ss and 5'ss effectively restores normal GLA (show NAT8 Antibodies) splicing

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. Study demonstrated that hnRNPA1 plays a critical and irreplaceable role in embryonic muscle development by regulating the expression and alternative splicing of muscle-related genes.

  2. hnRNPA1 is a critical regulator of vascular smooth muscle cell function and behavior in the context of neointima hyperplasia via miR (show MLXIP Antibodies)-124/IQGAP1 (show IQGAP1 Antibodies) regulatory axis.

  3. PRMT5 (show PRMT5 Antibodies) regulates internal ribosome entry site-dependent translation via methylation of hnRNP A1.

  4. Resveratrol causes a shift from the mesenchymal-specific forms of these factors to the respective epithelial forms and increases the expression of the RNA-binding proteins KHSRP (show KHSRP Antibodies) and hnRNPA1.

  5. this study identified hnRNPA1, an RNA-binding protein and auxiliary splicing factor (show SLU7 Antibodies), as a substrate of TRAF6 (show TRAF6 Antibodies); TRAF6 (show TRAF6 Antibodies) ubiquitination of hnRNPA1 regulated alternative splicing of Arhgap1 (show ARHGAP1 Antibodies), which resulted in activation of the GTP-binding (show RND2 Antibodies) Rho family protein Cdc42 (show CDC42 Antibodies) and accounted for hematopoietic defects in TRAF6 (show TRAF6 Antibodies)-expressing hematopoietic stem/ progenitor cells

  6. hnRNP A1 improves intestinal injury in anti-CD3 (show CD3E Antibodies) antibody-induced enteritis mice through the upregulation of TFF2 (show TFF2 Antibodies), which regulates apoptosis and enhances epithelial restoration

  7. Relevant to biological processes anticipated for hnRNP A1 and HuR (show ELAVL1 Antibodies).

  8. This study provides evidence that PCBP2 (show PCBP2 Antibodies) and hnRNP A1 bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  9. Heteronuclear ribonucleoprotein A1 interacts with an element that overlaps the 5' splice site of Mag (show MAG Antibodies) exon 12.

  10. MMP-3 (show MMP3 Antibodies)-triggered Rac1 splicing regulation is modulated by hnRNP A1

Pig (Porcine) Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. the swine HNRPA1 gene was moderately expressed in fat, spleen and kidney, weakly expressed in muscle and lung, and hardly expressed in small intestine, large intestine and liver.

Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Antigen Profile

Protein Summary

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

Gene names and symbols associated with HNRNPA1

  • heterogeneous nuclear ribonucleoprotein A1b (hnrnpa1b) antibody
  • heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) antibody
  • heterogeneous nuclear ribonucleoprotein A1 (LOC100101226) antibody
  • Heterogeneous nuclear ribonucleoprotein A1 (roa1) antibody
  • heterogeneous nuclear ribonucleoprotein A1 S homeolog (hnrnpa1.S) antibody
  • heterogeneous nuclear ribonucleoprotein A1 (hnrnpa1) antibody
  • heterogeneous nuclear ribonucleoprotein A1 (Hnrnpa1) antibody
  • heterogeneous nuclear ribonucleoprotein A1-like (LOC100359118) antibody
  • ribonucleoprotein A1a (hnrnpa1) antibody
  • D15Ertd119e antibody
  • Hdp antibody
  • hnrnp-A1 antibody
  • HNRNPA1 antibody
  • hnRNP A1 antibody
  • Hnrpa1 antibody
  • HNRPA1L3 antibody
  • ROA1 antibody
  • TPT1P antibody

Protein level used designations for HNRNPA1

heterogeneous nuclear ribonucleoprotein A1 , hnRNP core protein A1 , helix-destabilizing protein , single-strand-binding protein , hormonally upregulated Neu-associated kinase , Heterogeneous nuclear ribonucleoprotein A1 , heterogeneous ribonuclear particle protein , hnRNP A1 , Putative heterogeneous nuclear ribonucleoprotein A1-like 3 , heterogeneous nuclear ribonucleoprotein A1B protein , heterogeneous nuclear ribonucleoprotein B2 protein , heterogeneous nuclear ribonucleoprotein core protein A1 , hnRNP A1-like 3 , hnRNP core protein A1-like 3 , nuclear ribonucleoprotein particle A1 protein , single-strand DNA-binding protein UP1 , single-strand RNA-binding protein , HDP-1 , helix destabilizing protein , topoisomerase-inhibitor suppressed , UP1 , unwinding protein 1 , HDP , hnRNP A1-gamma isoform , heterogeneous nuclear ribonucleoproteins A1 homolog

GENE ID SPECIES
378453 Danio rerio
739306 Pan troglodytes
100101226 Bombyx mori
100195734 Salmo salar
380381 Xenopus laevis
496507 Xenopus (Silurana) tropicalis
3178 Homo sapiens
15382 Mus musculus
768103 Sus scrofa
505093 Bos taurus
29578 Rattus norvegicus
100359118 Oryctolagus cuniculus
100726972 Cavia porcellus
747284 Pan troglodytes
702977 Macaca mulatta
397751 Xenopus laevis
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