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Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Additionally we are shipping Hexamthylene Bis-Acetamide Inducible 2 Antibodies (42) and Hexamthylene Bis-Acetamide Inducible 2 Proteins (4) and many more products for this protein.
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HEXIM2 can functionally and quantitatively compensate for the loss of HEXIM1
utilization of HEXIM1 or HEXIM2 to bind and inhibit P-TEFb can be differentially regulated in vivo.
Positive transcription elongation factor b regulates eukaryotic gene expression at the level of elongation and is controlled by the reversible association with HEXIM2.
The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed.
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity).
, hexamethylene bis-acetamide-inducible protein 2
, hexamethylene-bis-acetamide-inducible transcript 2
, hexamthylene bis-acetamide inducible 2
, protein HEXIM2