anti-Histamine Receptor H4 (HRH4) Antibodies

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Additionally we are shipping Histamine Receptor H4 Kits (28) and Histamine Receptor H4 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRH4 59340 Q9H3N8
HRH4 170704 Q91ZY1
HRH4 225192 Q91ZY2
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Top anti-Histamine Receptor H4 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HRH4 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell HRH4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using HRH4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Image Histamine H4 Receptor antibody detects Histamine H4 Receptor protein by western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg Raji whole cell lysate/extract C. 30 μg NCI-H929 whole cell lysate/extract 10 % SDS-PAGE Histamine H4 Receptor antibody , dilution: 1:500 WB Image Histamine H4 Receptor antibody detects Histamine H4 Receptor protein by western blot analysis. A. 30 μg HeLa whole cell lysate/extract B. 30 μg whole cell lysate/extract of HRH4 shRNA-transfected HeLa cells 10 % SDS-PAGE Histamine H4 Receptor antibody , dilution: 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of human chronic myelogenous leukemia (K562) (lanes 1 and 3) and human promyelocytic leukemia (HL-60) (lanes 2 and 4) cell lysates: 1, 2. Anti-Human H4 Histamine Receptor (extracellular) antibody, (1:400). 3, 4. Anti-Human H4 Histamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Indirect flow cytometry analysis of H4 Histamine Receptor expression in live intact Jurkat (acute T-cell leukemia) cell lines <br />Black: Unstained cells + goat-anti-rabbit-PE. <br />Green: Cells+ Anti-Human H4 Histamine Receptor (extracellular) antibody, (1:20) + goat-anti-rabbit-PE. 0.2 mL Log in to see 10 to 11 Days
$832.43
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-HRH4 / Histamine H4 Receptor antibody  ABIN1048963 IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-HRH4 / Histamine H4 Receptor antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Anti-HRH4 / Histamine H4 Receptor antibody  ABIN1048964 IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-HRH4 / Histamine H4 Receptor antibody IHC of human Ovary, Carcinoma and Inflammatory Cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-HRH4 / Histamine H4 Receptor antibody  ABIN1048966 IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-HRH4 / Histamine H4 Receptor antibody IHC of human Colon, Carcinoma and Inflammatory Cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Histamine H4 R Antibody [NLS3775] - IHC analysis of Lymph node using this antibody at 12 ug/ ml. Immunohistochemistry-Paraffin: Histamine H4 R Antibody  - Anti-HRH4 / Histamine H4 Receptor antibody IHC of human Ovary, Carcinoma and Inflammatory Cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Log in to see 10 to 13 Days
$514.63
Details

More Antibodies against Histamine Receptor H4 Interaction Partners

Human Histamine Receptor H4 (HRH4) interaction partners

  1. Our novel scientific data provide further indication that histamine, in particular via the H4R, plays a potent role in the pathophysiology of allergic diseases through tight control of Th1 (show TH1L Antibodies)-Th2 mediator production favoring Th2 lymphocyte accumulation in inflamed tissues. Our results add to a growing evidence of data suggesting that the H4R may serve as a therapeutic target in allergic diseases.

  2. The expression of H4R was increased in peripheral blood monocytes in rheumatoid arthritis patients. Histamine and Th17 cytokines induced the osteoclast differentiation from monocytes and JNJ7777120 decreased the osteoclastogenesis.

  3. H1R (show HRH1 Antibodies) and H4R are useful biomarkers of allergic inflammation on the ocular surface. Most notably, H4R expressed on eosinophils is useful as a biomarker of eosinophilic inflammation of the ocular surface.

  4. Histamine stimulation influences the IL-17 (show IL17A Antibodies) pathway in psoriasis via the fourth histamine receptor subtype, H4R, on CD4 (show CD4 Antibodies)+ T cells.

  5. This study suggests that genetic variations within the HRH4 gene might be associated with special clinical features of psoriasis.

  6. Our findings provide evidence that HRH4 rs77485247 and rs77041280 polymorphisms may be associated with the risk of allergic rhinitis (AR) and the efficacy of H1 antihistamines for the treatment of AR patients.

  7. These data imply that the H4R regulates IgE-dependent processes in human basophils and provides a novel function of the H4R preventing an overwhelming immune reaction by engagement of a negative feedback loop.

  8. Pharmacological or genetic modulations of H2 and H4 HRs (H2R and H4R) not only suppressed gefitinib-induced cytostasis and differentiation of AML cells but also blocked EGFR and ERK1/2 inhibition in MDA-MB-231 cells

  9. Histamine H4 receptors could not be identified in five experimental models of the guinea-pig that are suited for the detection of presynaptic inhibitory receptors (hippocampus aorta, atrium, renal cortex and vas (show AVP Antibodies) deferens) whereas H3 receptors could be shown in the peripheral tissues but not in the hippocampus

  10. Taken together these data demonstrate that compound A and compound L may block H4R-mediated downstream signaling events.

Mouse (Murine) Histamine Receptor H4 (HRH4) interaction partners

  1. This study demonstrated that the phenotype of H4R(-)/(-) mice leads to increased neuropathic pain hypersensitivity promoting an overactivation of spinal ERK (show EPHB2 Antibodies)-CREB (show CREB1 Antibodies) pathway in DbetaH expressing neurons without modifying the innervation of the hind paw skin and integrity of the primary sensory neurons.

  2. H4R ligands have a beneficial effect in a model of lung fibrosis in the mouse, thus indicating that H4R antagonists or inverse agonists could be a novel therapeutic strategy for lung inflammatory diseases.

  3. Results illustrate that histamine H4 receptors (H4R) modulates various neurophysiological functions such as locomotor activity, anxiety, nociception and feeding behaviour, confirming the importance of the integrity and functionality of neuronal H4R in the histaminergic regulation of neuronal functions.

  4. These results identify the H4R as a new target controlling NK cell migration and NK cell-dendritic cell interaction in the skin during early allergic inflammation. These results further suggest that blocking the H4R in the skin might be beneficial in diseases like atopic dermatitis.

  5. Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis

  6. These results indicate a proinflammatory role of histamine via H4R in inflammatory bowel disease.

  7. The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis.

  8. H4R expression on murine keratinocytes was detected after stimulation with LPS (show TLR4 Antibodies) and peptidoglycan.

  9. the present study shows that H4 receptors potentially play a role in IgE induced FcepsilonRI (show FCER1A Antibodies) upregulation

  10. Acting via its H4 receptors, histamine impedes lipopolysaccharide-induced microglia migration and interleukin (IL)-1beta (show IL1B Antibodies) release under inflammatory challenge.

Guinea Pig Histamine Receptor H4 (HRH4) interaction partners

Histamine Receptor H4 (HRH4) Antigen Profile

Protein Summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HRH4

  • histamine receptor H4 (HRH4) antibody
  • histamine receptor H4 (Hrh4) antibody
  • AXOR35 antibody
  • BG26 antibody
  • GPCR105 antibody
  • GPRv53 antibody
  • H4 antibody
  • H4R antibody
  • HH4R antibody
  • HRH4 antibody

Protein level used designations for HRH4

G-protein coupled receptor 105 , SP9144 , histamine H4 receptor , pfi-013 , H4R , HH4R , histamine receptor H4 , histamine 4 receptor , histamine H4 receptor-like

GENE ID SPECIES
59340 Homo sapiens
170704 Rattus norvegicus
225192 Mus musculus
397224 Sus scrofa
468501 Pan troglodytes
490512 Canis lupus familiaris
702044 Macaca mulatta
769106 Gallus gallus
783354 Bos taurus
100034111 Equus caballus
100358525 Oryctolagus cuniculus
100379272 Cavia porcellus
100442858 Pongo abelii
Selected quality suppliers for anti-Histamine Receptor H4 (HRH4) Antibodies
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