Histone Acetyltransferase 1 (HAT1) ELISA Kits

The protein encoded by HAT1 is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Additionally we are shipping HAT1 Antibodies (111) and HAT1 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HAT1 8520 O14929
HAT1 296501 Q5M939
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Top HAT1 ELISA Kits at antibodies-online.com

Showing 4 out of 18 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.103 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse < 9.375 pg/mL 15.625 pg/mL - 1000 pg/mL   96 Tests Log in to see 11 to 18 Days
  1 kit Log in to see 11 to 12 Days

More ELISA Kits for HAT1 Interaction Partners

Human Histone Acetyltransferase 1 (HAT1) interaction partners

  1. High HAT1 expression is associated with Pancreatic ductal adenocarcinoma.

  2. In this work, we assessed the relationship between single-nucleotide polymorphisms (SNPs) of KAT1, KAT2 and IDO1 gene encoding, and the risk of depression development. Our study was performed on the DNA isolated from peripheral blood of 281 depressed patients and 236 controls. We genotyped, by using TaqMan probes, four polymorphisms.

  3. HAT gene expression is required for cisplatin resistance and Clock and Tip60 regulate not only transcription, but also DNA repair, through periodic histone acetylation

  4. Human histone acetyltransferase 1 (Hat1) acetylates lysine 5 of histone H2A in vivo.

  5. The high-resolution crystal structure of a Hat1p/Hat2p/CoA/H4 peptide complex was solved and it was found that the H4 tail interacts with both Hat1p and Hat2p, by which substrate recruitment is facilitated. It was discovered that H3 N-terminal peptides can bind to the Hat2p WD40 domain.

  6. Signalling from Toll-like or TNF-alpha receptors triggers the calcium/calmodulin-dependent protein kinase (CaMK2) to activate histone acetyltransferase-1 (HAT1), which then acetylates the transcriptional regulator PLZF. Acetylation of PLZF promotes the assembly of a repressor complex incorporating HDAC3 and the NF-kappa B p50 subunit that limits the NF-kappa B response.

  7. HAT1 is involved in the STAT5 binding to the Bcl2L12 promoter. HAT1 increased the expression of Bcl2L12. Bcl2L12 mediated the effects of HAT1 on suppressing NPC cell apoptosis. Absorption of the HAT1 shRNA plasmid-carrying liposomes induced NPC cell apoptosis. In conclusion, inhibition of HAT1 can induce NPC cell apoptosis via increasing Bcl2L12 expression, which can be a potential therapy for NPC treatment.

  8. HAT1 was upregulated in hepatocellular carcinoma.HAT1 acts as an oncogenic protein promoting cell proliferation and inducing cisplatin resistance in hepatocellular carcinoma.

  9. Nuclear HDAC2 immunopositivity was significantly higher in actinic cheilitis (AC) when compared with lip squamous cell carcinoma (LSCC). HDAC1 and HAT1 nuclear immunostaining were higher in AC, with no statistical significance. When comparing data with our previous study, we found a positive correlation between HDAC1 X DNMT1/DNMT3b, HDAC2 X DNMT3b, and HAT1 X DNMT1/DNMT3b for certain studied groups.

  10. Data show that PP32 and SET/TAF-Ibeta proteins block HAT1-mediated H4 acetylation.

  11. AMPK phosphorylates DNMT1, RBBP7, and HAT1 and increases interactions of DNMT1, RBBP7, and HAT1.

  12. Results show a novel interaction of the Lsm4 RGG domain with HAT1 and RBBP7, leading to the possibility of a posttranslational modifications network involved in mRNP regulation.

  13. These data indicated that miR-486 aggravate the cholesterol accumulation in THP-1 cells by targeting HAT1.

  14. The expression of HAT1 was higher in the primary Esophageal carcinoma tumors and adjacent tissue as compared to that of the normal esophageal tissue and HAT1 expression was directly correlated with the poor tumor differentiation

  15. Data indicate that HAT1 is required for homologous recombination in DNA repair.

  16. HAT1 differentially impacts nucleosome assembly of H3.1-H4 and H3.3-H4.

  17. the role of Hat1 in DNA damage repair is evolutionarily conserved, the ability of H3 acetylation to compensate for Hat1 deletion appears to be more variable

Candida albicans Histone Acetyltransferase 1 (HAT1) interaction partners

  1. we discover a novel function for the chromatin assembly-associated histone acetyltransferase complex NuB4 catalytic subunit HAT1 in oxidative stress response, antifungal drug tolerance as well as in fungal virulence

  2. findings show that C. albicans requires a fully functional HAT1 complex for efficient repair of DNA damages, normal cell proliferation and maintenance of the yeast morphology.

HAT1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with HAT1

  • histone acetyltransferase 1 (HAT1) antibody
  • histone acetyltransferase 1 (Hat1) antibody
  • histone acetyltransferase of the GNAT family 2 (HAG2) antibody
  • histone acetyltransferase 1 (hat1) antibody
  • histone acetyltransferase catalytic subunit (HAT1) antibody
  • histone acetyltransferase Hat1 (hat1) antibody
  • histone acetyltransferase 1 L homeolog (hat1.L) antibody
  • HAC07 antibody
  • HAC7 antibody
  • hac106 antibody
  • HAG02 antibody
  • hat1 antibody
  • histone acetyltransferase of the GNAT family 2 antibody
  • KAT1 antibody
  • MIK19.19 antibody
  • MIK19_19 antibody
  • zgc:92639 antibody

Protein level used designations for HAT1

histone acetyltransferase type B catalytic subunit , histone aminotransferase 1 , CL1399_1 , CL1399_1_ov , HAT B , hac109 , hag102 , hat-B-50 , hatB1 , hatb , histone acetyl transferase , mcg4291 , std614030B05 , hypothetical protein , histone acetyltransferase 1 L homeolog

8520 Homo sapiens
296501 Rattus norvegicus
374037 Gallus gallus
835775 Arabidopsis thaliana
542083 Zea mays
3644770 Candida albicans SC5314
100732060 Cavia porcellus
2542502 Schizosaccharomyces pombe 972h-
478799 Canis lupus familiaris
447734 Xenopus laevis
509329 Bos taurus
100861370 Capra hircus
447833 Danio rerio
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