Histone Cluster 3, H3 Proteins (HIST3H3)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.

list all proteins Gene Name GeneID UniProt
Human HIST3H3 HIST3H3 8290 Q16695
Mouse HIST3H3 HIST3H3 260423 P84228
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Top Histone Cluster 3, H3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 0.25 mg Log in to see Available
Yeast Candida albicans His tag   1 mg Log in to see 60 to 71 Days
Yeast Tetrahymena His tag   1 mg Log in to see 60 to 71 Days
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 60 to 71 Days
Escherichia coli (E. coli) Various Species His tag 100 μg Log in to see 15 to 18 Days

More Proteins for Histone Cluster 3, H3 (HIST3H3) Interaction Partners

Human Histone Cluster 3, H3 (HIST3H3) interaction partners

  1. Data suggest that Ki-67 (show MKI67 Proteins) antigen proliferative index has important limitations and hhosphohistone H3 (PHH3) is an alternative proliferative marker.

  2. This data indicates that, in the early developing human brain, HIST1H3B constitutes the largest proportion of H3.1 transcripts among H3.1 isoforms.

  3. Data suggest TCF19 (show TCF19 Proteins) interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger; TCF19 (show TCF19 Proteins) expression appears to regulate gluconeogenesis in hepatocytes; TCF19 (show TCF19 Proteins) interacts with CHD4 (show CHD4 Proteins) causing NuRD complex recruitment to gene promoters of enzymes involved in gluconeogenesis. (TCF19 (show TCF19 Proteins) = transcription factor 19 (show TCF19 Proteins); CHD4 (show CHD4 Proteins) = chromodomain helicase DNA binding protein 4 (show CHD4 Proteins); NuRD = nucleosome-remodeling-deacetylase)

  4. This series of 47 diffuse midline gliomas, histone H3-K27M mutation was mutually exclusive with IDH1 (show IDH1 Proteins)-R132H mutation and EGFR (show EGFR Proteins) amplification, rarely co-occurred with BRAF (show BRAF Proteins)-V600E mutation, and was commonly associated with p53 (show TP53 Proteins) overexpression, ATRX (show ATRX Proteins) loss, and monosomy 10. Among these K27M+ diffuse midline gliomas.

  5. Data show that histone chaperone HIRA (show HIRA Proteins) co-localizes with viral genomes, binds to incoming viral and deposits histone H3.3 (show H3F3A Proteins) onto these.

  6. These experiments showed that PHF13 (show PHF13 Proteins) binds specifically to DNA and to two types of histone H3 methyl tags (lysine 4-tri (show VANGL2 Proteins)-methyl or lysine 4-di-methyl) where it functions as a transcriptional co-regulator.

  7. Hemi-methylated CpGs DNA recognition activates UHRF1 (show UHRF1 Proteins) ubiquitylation towards multiple lysines on the H3 tail adjacent to the UHRF1 (show UHRF1 Proteins) histone-binding site.

  8. We describe, for the first time, the MR imaging features of pediatric diffuse midline gliomas with histone H3 K27M mutation

  9. Approximately 30% of pediatric high grade gliomas (pedHGG) including GBM and DIPG harbor a lysine 27 mutation (K27M) in histone 3.3 (H3.3) which is correlated with poor outcome and was shown to influence EZH2 (show EZH2 Proteins) function.

  10. Data suggest that, during monocyte-into-macrophage differentiation, extensive trimethylation of histone H3 lysine 4 as well as histone H3 lysine 27 promotes occupancy of histone H3 at promoters of transcription factors such as HOXA (homeodomain proteins) and FOXO (forkhead transcription factors).

Mouse (Murine) Histone Cluster 3, H3 (HIST3H3) interaction partners

  1. Histone H3.3K27M and Trp53 (show TP53 Proteins) loss and PDGFRA (show PDGFRA Proteins) overexpression accelerates disease onset and increases tumor invasion.

  2. Histone H3 arginine 2 dimethylation lysine 4 trimethylation, not simply H3lysine 4 trimethylation alone, is the mark of active promoters

  3. Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha (show PPARA Proteins) network.

  4. Increased levels of decondensed chromatin in both normal progenitor cells and cancer cells are associated with global loss of H3K27me3, which is linked to MYC (show MYC Proteins) overexpression.

  5. histone H3 phosphorylation may be a molecular signature of the activated, retinoid-controlled mRARbeta2 gene promoter

  6. differential regulation between gene expression and histone H3 acetylation in the variable regions of the TCRbeta locus

  7. Rb effects permanent cell cycle exit in part by maintaining trimethylation of histone H3 lysine 27 (H3K27) on cell cycle genes.

  8. Pygo2 (show PYGO2 Proteins) controls pattern of histone H3 hyperacetylation

  9. Here we show that cAMP signaling regulates histone H3 phosphorylation in a cell cycle-dependent fashion, increasing it in quiescent cells but dramatically reducing it in cycling cells

  10. Bmi1 (show BMI1 Proteins), which methylate H3K27, were present on the HSV-1 genome during latency.

Histone Cluster 3, H3 (HIST3H3) Protein Profile

Protein Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Gene names and symbols associated with HIST3H3

  • histone cluster 3 H3 (HIST3H3)
  • histone cluster 1 H3 family member a (HIST1H3A)
  • histone cluster 3, H3 (HIST3H3)
  • histone cluster 1, H3f (Hist1h3f)
  • H3.2-221 protein
  • H3.4 protein
  • H3/A protein
  • H3/g protein
  • H3FA protein
  • H3FT protein
  • H3t protein
  • Hist1 protein

Protein level used designations for HIST3H3

H3 histone family, member T , H3/t , histone 3, H3 , histone H3.1t , H3 histone family, member A , histone 1, H3a , histone H3.1 , histone H3/a , histone cluster 3, H3 , histone 1, H3f , histone H3 , histone H3.2 , histone gene complex 1

8290 Homo sapiens
8350 Homo sapiens
480760 Canis lupus familiaris
260423 Mus musculus
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