anti-Homeobox A13 (HOXA13) Antibodies

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping Homeobox A13 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HOXA13 500129  
HOXA13 3209 P31271
HOXA13 15398 Q62424
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Top anti-Homeobox A13 Antibodies at

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-HOXA13 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of HOXA13 / HOX1J Antibody (C-term) in Y79 cell line lysates (35ug/lane). This demonstrates the HOXA13 antibody detected the HOXA13 protein (arrow). 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
Human Rabbit Un-conjugated WB Western blot analysis in Y79 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using HOXA13 antibody. 100 μL 11 to 13 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti-HOXA13 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
Human Rabbit Un-conjugated IF, WB Western blot analysis of extracts of various cells, using HOXA13 antibody. 100 μL 6 to 11 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using HOXA13 antibody. 200 μL 12 to 14 Days
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days

Top referenced anti-Homeobox A13 Antibodies

  1. Dog (Canine) Polyclonal HOXA13 Primary Antibody for WB - ABIN2777518 : Villavicencio-Lorini, Kuss, Friedrich, Haupt, Farooq, Türkmen, Duboule, Hecht, Mundlos: Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. in The Journal of clinical investigation 2010 (PubMed)

More Antibodies against Homeobox A13 Interaction Partners

Human Homeobox A13 (HOXA13) interaction partners

  1. Significant decrease in the expression of the genes HOXA13 and COL3A in the uterosacral ligaments in advanced stages of prolapse, indicates that these gene expressions may play a role in the development of uterine prolapse.

  2. Homeobox A13 (HOXA13) played a role of carcinogenesis through directly down-regulating dehydrogenase/reductase 2 (DHRS2) to increase proto-oncogene proteins c-mdm2 (MDM2).

  3. High HOXA13 expression was associated with inferior tumor regression grade and poor overall survival in esophageal squamous cell carcinoma (ESCC) patients treated with neoadjuvant chemotherapy. HOXA13 increased cisplatin-resistance and promoted epithelial-to-mesenchymal transition in ESCC cells.

  4. Data suggest that patients with HOXA13-positive hepatocellular carcinomas experience worse overall survival than those with HOXA13-negative HCC; HOXA13 and HOTTIP (know regulator of HOXA13 expression) are expressed in the same neoplastic hepatocyte populations. (HOTTIP = long noncoding RNA HOTTIP)

  5. prognostic value of HOXA13 in solid tumors

  6. HOXA13 is an unfavorable prognostic factor and a novel oncogene for prostate cancer.

  7. Our study indicated that alteration of EPHA7 promoter transactivation produced by missensemutations of HOXA13 provided a molecular basis for HFGS.

  8. Findings indicate that the recruitment of HOXA13-HOTTIP and HOXA13-HOTAIR to different sites in the BMP7 promoter is crucial for the oncogenic fate of human gastric cells.

  9. The results of our study show that high expression of HOXA13 is associated with the progression of bladder cancer and that HOXA13 might serve as a biomarker for prognosis of bladder cancer.

  10. Knockdown of HoxA13 caused the downregulation of long non-coding RNA HOTTIP and insulin growth factor-binding protein 3 (IGFBP-3) genes, indicating that both were targets of HoxA13.

  11. Findings indicated that HOTTIP modulated HOXA13 at both the transcriptional and posttranscriptional levels in ESCC cells.

  12. HoxA13 increases myometrial cell contractility by enhancing the secretion of IL-1beta, resulting in an up-regulation of CAP and other proinflammatory cytokine expression.

  13. using both knockdown and knockout approaches we show that Hottip expression is required for activation of the 5' Hoxa genes (Hoxa13 and Hoxa10/11) and for retaining Mll1 at the 5' end of Hoxa. Moreover, we demonstrate that artificially inducing Hottip expression is sufficient to activate the 5' Hoxa genes and that Hottip RNA binds to the 5' end of Hoxa

  14. HOXA13 is involved in HSAinduced EMT in HKC cells and upregulation of HOXA13 exerts a beneficial effect in EMT, which may be associated with the GR signaling pathway.

  15. expression levels of HOTTIP and HOXA13 were both higher in gastric cancer which was poorly differentiated, at advanced TNM stages and exhibited lymph node-metastasis. Spearman analyses indicated that HOTTIP and HOXA13 had a highly positive correlation both in non-tumor mucosae and cancer lesions. Collectively, these findings suggest that HOTTIP and HOXA13 play important roles in gastric cancer progression.

  16. Down-regulation of HOTTIP and HOXA13 was associated with cell growth and cell cycle, and exerts tumor-suppressive functions in the genesis and progression of prostate cancer, providing a potential attractive therapeutic approach for this malignancy.

  17. Atypical hand-foot-genital syndrome and developmental delay due to de novo mutations in HOXA13 and NRXN1

  18. HOXA13 promotes glioma progression in part via Wnt- and TGF-beta-induced epithelial-mesenchymal transition

  19. This pregnancy-maintaining regionalization of myometrial function may be mediated by HoxA13

  20. Transfection of HOXA13 in HKCs could inhibit the degree of EMT induced by albumin-overload, possibly by increasing BMP-7 expression.

Mouse (Murine) Homeobox A13 (HOXA13) interaction partners

  1. we report on the genome-wide profiling of HOXA13 and HOXD13 in vivo binding and changes of the transcriptome and chromatin state in the transition from the early to the late-distal limb developmental program, as well as in Hoxa13(-/-); Hoxd13(-/-) limbs.

  2. Data show that almost all muscle masses of the zeugopod (forearm) and part of the triceps contain homeobox protein HOXA13-expressing cells and/or their descendants.

  3. Defects in interdigital programmed cell death and digit separation in Hoxa13 mutant mice may be caused in part by reduced levels of RA signaling stemming from a loss in the direct regulation of Aldh1a2

  4. The data demonstrate that simvastatin contributes to prevent the progression of renal fibrosis by upregulating BMP-7-mediated anti-fibrotic signaling and that one aspect of crucial efficacies is achieved by regulating HOXA13 and USAG-1.

  5. The results show that overactivation of hedgehog signaling leads to abnormal development of the female reproductive tract, altered levels of Hoxa13 and Wnt5a mRNA, and an aberrant inflammatory response to mating.

  6. Data show that the extra-embryonic function of Hoxa10, -11, and -13 genes stems from their specific expression in the allantois, an extra-embryonic hallmark of amniote vertebrates.

  7. Data show that cis-regulatory elements driving Hoxd gene expression in distal limbs are present in fish.

  8. specific role during appendicular skeletal development

  9. complete NMR chemical shift assignments of the mouse HOXA13 DNA binding domain

  10. HoxA-13 regulates transcription through multiple pathways

  11. Hoxa13 has a role in the vascularization of the glans penis is also identified

  12. Hoxa-11 and Hoxa-13 are involved in the negative regulation of MyoD expression in limb muscle precursors

  13. Immunoprecipitation of HOXA13-bone morphogenetic protein 2 and HOXA13-bone morphogenetic protein 7 enhancer complexes from the developing autopod confirm that endogenous HOXA13 associates with these regions

  14. Microarray analysis identified 68 genes with significant, reproducible RNA expression changes in stable HOXA13-expressing cells.

  15. EphA7 is a direct downstream target of Hoxd13 and Hoxa13 during limb development

  16. the high affinity HOXA13 binding site deduced by quantitative analyses is used in vivo to facilitate HOXA13 target gene regulation, providing a critical advance toward understanding the molecular basis for defects associated with loss of HOXA13 function

  17. HOXA13 directly regulates EphA6 and EphA7 in the developing genital tubercle.

  18. The distal-specific gene HOXA13 is continually required to maintain the distal-specific transcriptional program in adult fibroblasts

  19. At least two sequences remote to the HoxA cluster are required collectively to drive Hoxa13-like expression in developing distal limbs.

  20. the antagonistic interaction between Hoxa13-Hoxd13 and Sall1-Sall3 in the developing limb may contribute to the fine-tuning of local Hox activity that leads to proper morphogenesis of each cartilage element of the vertebrate autopod.

Homeobox A13 (HOXA13) Antigen Profile

Protein Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.

Gene names and symbols associated with anti-Homeobox A13 (HOXA13) Antibodies

  • homeobox A13 (HOXA13) antibody
  • homeo box A13 (Hoxa13) antibody
  • homeobox A13 (Hoxa13) antibody
  • Hd antibody
  • Hox-1.10 antibody
  • HOX1 antibody
  • HOX1J antibody
  • HOXA13 antibody
  • RGD1562483 antibody

Protein level used designations for anti-Homeobox A13 (HOXA13) Antibodies

homeobox A13 , homeo box 1J , homeo box A13 , homeobox protein HOXA13 , homeobox protein Hox-1J , homeobox protein Hox-A13 , transcription factor HOXA13 , homeobox protein Hox-1.10 , hypodactyly , HOX protein , Hox A13

482375 Canis lupus familiaris
619386 Monodelphis domestica
100137365 Papio anubis
100225497 Taeniopygia guttata
500129 Rattus norvegicus
3209 Homo sapiens
15398 Mus musculus
373934 Gallus gallus
100359352 Sus scrofa
787194 Bos taurus
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