Homeobox A2 Proteins (HOXA2)

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping HOXA2 Antibodies (47) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HOXA2 3199 O43364
HOXA2 15399 P31245
HOXA2 103690123 P31246;
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Top HOXA2 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Yeast REACT_Eastern Newt His tag   1 mg 60 to 71 Days
Yeast Heterodontus francisci His tag   1 mg 60 to 71 Days
Yeast Rat His tag   1 mg 60 to 71 Days
Yeast Cow His tag   1 mg 60 to 71 Days
Yeast Callithrix jacchus His tag   1 mg 60 to 71 Days
Yeast Primates His tag   1 mg 60 to 71 Days

HOXA2 Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

Rat (Rattus)

More Proteins for Homeobox A2 (HOXA2) Interaction Partners

Human Homeobox A2 (HOXA2) interaction partners

  1. Performed mutational analysis of TCOF1, GSC, and HOXA2 to determine the mutational features of the 3 genes in Chinese patients with Treacher Collins syndrome.

  2. The role of HOXA2 gene in dominant isolated microtia and the dysmorphogenetic effect of this gene on ear development

  3. 5 genomic variants in GSC, HOXA2 and PRKRA were identified through mutational analysis in Chinese patients with microtia.

  4. The Hoxa2-mediated decay of RCHY1 involves both the 19S and 20S proteasome complexes

  5. HOXA2 acts as a suppressor or TBP-antagonist to inhibit MMP-9 expression; while methylation-mediated inactivation of HOXA2 in NPC derepresses MMP-9 production and increases invasion of NPC cells.

  6. we have identified a nonsense mutation (Q235*) in HOXA2 that segregates with bilateral nonsyndromic microtia and hearing loss through three generations of a family in an autosomal dominant pattern.

  7. Lack of mutations in the coding region of HOXA2 among the sporadic microtia patients.

  8. A missense mutation in the HOXA2 in a consanguineous iranian family with bilateral microtia was reported.

Mouse (Murine) Homeobox A2 (HOXA2) interaction partners

  1. Study demonstrates that Hoxa-2 protein express in all ossicular blastemata of the mouse embryo, which could suggest a contribution of second arch cells to the entire ossicular chain.

  2. These results establish a role for Hox factors in tonotopic refinement of connectivity and in ensuring the precision of sound transmission in the mammalian auditory circuit.

  3. Hoxa2, Meis and Pbx proteins act cooperatively on the ECR, via a core 32 bp sequence, to regulate Hmx1 expression.

  4. our data support that KPC2 regulates Hoxa2 by promoting its relocation to the cytoplasm.

  5. Ectopic Hoxa2 expression results in the transformation of the proximal Meckel's cartilage and the malleus into a supernumerary styloid process (SP), a second pharyngeal arch-derived mammalian-specific skeletal structure.

  6. Hoxa2 operates as a tissue-specific cofactor, enhancing Meis binding to specific sites that provide the second arch with its anatomical identity

  7. The impairment of chondrogenic differentiation by Hoxa2 overexpression.

  8. Data show that the transcription factor Hoxa2 binds to Pcp4 chromatin and regulates Pcp4 expression in the second arch.

  9. Hoxa2 partly controls the morphogenesis of the pinna through the BMP signalling pathway and expression of Eya1, which in humans is involved in branchio-oto-renal syndrome.

  10. Hoxb2 antagonizes Hoxa2 during rostral hindbrain oligodendrogenesis.

  11. the sustained expression of Hoxa2 in the chondrocyte lineage is characterized by a proportionate short stature resulting from skeletal growth defect.

  12. The data reveals that Hoxa2 has large genome coverage and potentially regulates thousands of genes.

  13. The inhibition of miR-3960 expression attenuated the osteoblastogenesis. Homeobox A2 (Hoxa2), a repressor of Runx2 expression, was confirmed to be a target of miR-3960.

  14. Meox1 expression is downregulated in the second arch of Hoxa2 mouse mutant embryos.

  15. The Satb2 gene was down-regulated and the Hoxa2 gene was up-regulated in phenytoin-treated mouse embryonic craniofacial tissue.

  16. Hoxa2 enhancer 2 contains a critical Hoxa2 responsive regulatory element

  17. although Hoxa2 is expressed throughout oligodendrocyte development, it does not appear to be critical for early stages of oligodendrogenesis in the murine spinal cord

  18. Hoxa2 regulation of Six2 is confined to a 0.9 kb fragment of the Six2 promoter and that Hoxa2 binds to this promoter region

  19. Hoxa2 is selectively required in cranial neural crest cells (NCCs)

  20. Hoxa2- and rhombomere 3-dependent cues determine the whisker area map and are required for the assembly of the whisker-to-barrel somatosensory circuit

Xenopus laevis Homeobox A2 (HOXA2) interaction partners

  1. Hoxa2 knockdown in Xenopus results in hyoid to mandibular homeosis.

HOXA2 Protein Profile

Protein Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.

Gene names and symbols associated with Homeobox A2 Proteins (HOXA2)

  • homeobox A2 (HOXA2)
  • homeobox A2 (Hoxa2)
  • homeobox A2 L homeolog (hoxa2.L)
  • homeobox A2 S homeolog (hoxa2.S)
  • homeobox A2 (hoxa2)
  • homeo box A2 (Hoxa2)
  • homeobox A2b (hoxa2b)
  • AI324701 protein
  • hox-1.11 protein
  • Hox-A2 protein
  • HOX1.11 protein
  • hox1k protein
  • Hoxa-2 protein
  • HOXA2 protein
  • hoxa2b protein
  • hoxa2b-A protein
  • Hoxa11 protein
  • MGC154497 protein
  • RATHOX111A protein
  • X-Hoxa2 protein
  • Z-75 protein

Protein level used designations for Homeobox A2 Proteins (HOXA2)

homeobox protein Hox-1K , homeobox protein Hox-A2 , homeo box A2 , homeobox protein Hox-1.11 , homeobox A2 , transcription factor Hoxa2b , transcription factor Hoxa2 , Homeobox protein Hox-A2 , homeobox protein Hox-A2-like , Homeobox gene A11 , Homeobox gene A2 , Homeobox protein Hox-1.11 , etID309949.16 , homeo box A2b , homeobox gene A-2 , homeobox protein Hox-A2b , hox-A2

3199 Homo sapiens
15399 Mus musculus
373836 Xenopus laevis
396055 Gallus gallus
399169 Xenopus laevis
472322 Pan troglodytes
524150 Bos taurus
609592 Canis lupus familiaris
700605 Macaca mulatta
100010189 Monodelphis domestica
100038099 Xenopus (Silurana) tropicalis
100137359 Papio anubis
100328783 Oryctolagus cuniculus
100399103 Callithrix jacchus
100587863 Nomascus leucogenys
103690123 Rattus norvegicus
30325 Danio rerio
100719038 Cavia porcellus
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