ITPK1 Proteins

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.

Data Quality
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Type
  • 11
    Protein
Antigen
  • 11
Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
  • 1
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Protein Type
  • 11
Format
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  • 4
Suggested next Filters
11 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3093199
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3136320
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2130186
$564.71
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1308246
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN1098354
$646.15
Plus shipping costs $45.00
Delivery in 15 to 19 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2723914
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2723915
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityEntamoeba histolytica (E. histolytica)
Application ELISA
Order details Cat. No. ABIN1659096
$2,856.33
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityZebrafish (Danio rerio)
Application ELISA
Order details Cat. No. ABIN1677535
$3,094.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityChicken
Application ELISA
Order details Cat. No. ABIN1630973
$3,129.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1459571
$3,166.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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ITPK1 Protein Profile

Protein Summary

Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.

Gene names and symbols associated with ITPK1

  • inositol-tetrakisphosphate 1-kinase (ITPK1) antibody
  • inositol 1,3,4-triphosphate 5/6 kinase (Itpk1) antibody
  • inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L) antibody
  • inositol-tetrakisphosphate 1-kinase a (itpk1a) antibody
  • inositol-tetrakisphosphate 1-kinase (Itpk1) antibody
  • BC031182 antibody
  • ITRPK1 antibody
  • wu:fj15d08 antibody
  • zgc:56075 antibody

Protein level used designations for ITPK1

inositol 1,3,4-triphosphate 5/6 kinase , inositol 1,3,4-trisphosphate 5/6 kinase , inositol 1,3,4-trisphosphate 5/6-kinase , inositol-triphosphate 5/6-kinase , ins(1,3,4)P(3) 5/6-kinase , inositol-tetrakisphosphate 1-kinase

GENE ID SPECIES
3705 Homo sapiens
217837 Mus musculus
379828 Xenopus laevis
406290 Danio rerio
423421 Gallus gallus
500709 Rattus norvegicus
518488 Bos taurus
100152339 Sus scrofa
100717610 Cavia porcellus
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