Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) ELISA Kits

IGF2BP2 encodes a member of the IGF-II mRNA-binding protein (IMP) family. Additionally we are shipping IGF2BP2 Antibodies (154) and IGF2BP2 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IGF2BP2 10644 Q9Y6M1
Anti-Mouse IGF2BP2 IGF2BP2 319765 Q5SF07
Anti-Rat IGF2BP2 IGF2BP2 303824  
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Top IGF2BP2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 31.25 pg/mL 125-8000 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Details

More ELISA Kits for IGF2BP2 Interaction Partners

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) interaction partners

  1. miR-181a-5p suppresses the invasion and migration of cytotrophoblasts, and its inhibitory effects were at least partially mediated by the suppression of IGF2BP2 expression

  2. Study generated a high-resolution, genome-wide map of chromatin architecture in pancreatic islets and used this map to annotate candidate target genes of islet enhancers. At the IGF2BP2 locus, type 2 diabetes risk alleles reduce islet chromatin accessibility and expression of target gene IGF2BP2 and that conditional knockout of IGF2BP2 homolog Imp2 in mouse islets impairs glucose-stimulated insulin secretion.

  3. neither rs4402960 nor rs11705701 associated with gestational diabetes; rs4402960 and/or rs11705701 may affect length of gestation and Apgar score of newborn

  4. The direct binding of IGF2BPs to RNA N(6)-methyladenosine through their KH domains enhances mRNA stability and translation.

  5. IGF2BP2 and HMGA2 are significantly upregulated in metaplastic carcinoma compared to other breast cancer subtypes.

  6. The results showed that IGF2BP2 was overexpressed in Acute Myelocytic Leukemia patients.

  7. Data show that insulin-like growth factor-II mRNA-binding protein 2 and 3 (IMP2/3)-miR-200a-progesterone receptor axis represents a double-negative feedback loop and serves as a new potential therapeutic target for the treatment of Triple-negative breast cancer (TNBC).

  8. IGF2BP2 protein is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1.

  9. The miR-485-5p/IGF2BP2 axis orchestrates the growth and metastasis of non-small cell lung cancer.

  10. IGF2BP2/IMP2 expression is linked to short survival and metastasis in esophageal adenocarcinoma

  11. insulin-like growth factor 2 mRNA-binding protein 2 (IMP2) binds to let-7 miRNA recognition elements (MREs) and prevents let-7 target gene silencing.

  12. miR-1193 suppressed proliferation and invasion of human breast cancer cells via translational suppression of IGF2BP2.

  13. Our data suggests that IGF2BP2 polymorphisms are associated with Type 2 Diabetes Mellitus in Asian populations.

  14. Study conclude that integration of genomic and transcriptomic data implicate circulating IGF2BP2 mRNA levels associated with glucose and insulin homeostasis

  15. IGF2BP2 as a post-transcriptional regulatory mRNA-binding factor that contributes to Colorectal carcinogenesis.

  16. p62/IMP2 stimulates cell migration and reduces cell adhesion, contributing to breast cancer progression.

  17. IMP2 expression is higher in ovarian and endometrial high-grade serous carcinomas (HGSC) than in ovarian or endometrial endometrioid carcinoma. Knockdown in ovarian HGSC cell line decreased cell proliferation.

  18. Our results suggest IGF2BP2 and KCNQ1 polymorphisms might be independent predictors of chemotherapeutic response

  19. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion

  20. Imp2 regulates the activity of IGF2, which further activates PI3K/Akt signaling.

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) interaction partners

  1. Study generated a high-resolution, genome-wide map of chromatin architecture in pancreatic islets and used this map to annotate candidate target genes of islet enhancers. At the IGF2BP2 locus, type 2 diabetes risk alleles reduce islet chromatin accessibility and expression of target gene IGF2BP2 and that conditional knockout of IGF2BP2 homolog Imp2 in mouse islets impairs glucose-stimulated insulin secretion.

  2. The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis.

  3. results reveal a highly distinctive axonal enrichment of IMP2, show that it interacts with a network of axon guidance-related mRNAs, and reveal that it is required for normal axon pathfinding during vertebrate development.

  4. these results highlight the previously undiscovered and crucial role of the HMGB2-IGF2BP2 axis in myogenesis and muscle regeneration.

  5. p62/IMP2 promotes hepatocarcinogenesis by an amplification of inflammation.

  6. IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins.

  7. p62/IGF2BP2-2 drives the progression of NAFLD through elevation of hepatic iron deposition and increased production of hepatic free cholesterol.

  8. Mice with a liver overexpression of insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IMP2-2/IGF2BP2-2 show elevated Ccl2 levels, which models all stages of non-alcoholic fatty liver disease.

  9. data demonstrate that the HMGA2-IGF2BP2 axis functions as a key regulator of satellite cell activation and therefore skeletal muscle development

  10. oncofetal insulin-like growth factor 2 mRNA-binding protein 2 (IMP2, IGF2BP2) regulates oxidative phosphorylation (OXPHOS) in primary glioblastoma (GBM) sphere cultures (gliomaspheres)

  11. Dual phosphorylation of IMP2 at the mTOR sites is evident in the mouse embryo, likely coupling nutrient sufficiency to IGF2 expression and fetal growth

IGF2BP2 Antigen Profile

Antigen Summary

This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with IGF2BP2

  • insulin like growth factor 2 mRNA binding protein 2 (IGF2BP2) antibody
  • insulin-like growth factor 2 mRNA binding protein 2 (Igf2bp2) antibody
  • C330012H03Rik antibody
  • IMP-2 antibody
  • Imp2 antibody
  • Neilsen antibody
  • p62 antibody
  • RGD1305614 antibody
  • VICKZ2 antibody

Protein level used designations for IGF2BP2

IGF-II mRNA-binding protein 2 , IGF2 mRNA-binding protein 2 , VICKZ family member 2 , hepatocellular carcinoma autoantigen p62 , insulin-like growth factor 2 mRNA-binding protein 2 , insulin-like growth factor 2, binding protein 2 , IMP-2

GENE ID SPECIES
10644 Homo sapiens
478662 Canis lupus familiaris
319765 Mus musculus
519028 Bos taurus
303824 Rattus norvegicus
100172487 Pongo abelii
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