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The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. Additionally we are shipping IL17A Antibodies (514) and IL17A Proteins (94) and many more products for this protein.
Showing 10 out of 114 products:
Human IL17A ELISA Kit for Sandwich ELISA - ABIN411314
Tan, Liu, Yang, Wang, Qin: An inactivated Pseudomonas aeruginosa medicament inhibits airway allergic inflammation and improves epithelial functions. in The journal of physiological sciences : JPS 2012
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Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN411315
Kotake, Udagawa, Takahashi, Matsuzaki, Itoh, Ishiyama, Saito, Inoue, Kamatani, Gillespie, Martin, Suda: IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. in The Journal of clinical investigation 1999
Show all 11 Pubmed References
Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN625138
Nakai, Yoneda, Hosokawa, Moriue, Presland, Fallon, Kabashima, Kosaka, Kubota: Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies. in The American journal of pathology 2012
Show all 7 Pubmed References
Human IL17A ELISA Kit for Sandwich ELISA - ABIN365737
Deng, Chen, Zheng, Chen, Huang, Yin, Gao, Lin, Huang, Gao, Yu, Liu: Association of BAFF and IL-17A with subphenotypes of primary Sjögren's syndrome. in International journal of rheumatic diseases 2015
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Human IL17A ELISA Kit for Sandwich ELISA - ABIN1446085
Lu, Nossent: Thrombopoietin levels in systemic lupus erythematosus are linked to inflammatory cytokines, but unrelated to thrombocytopenia or thrombosis. in Lupus 2014
Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN1446148
Rosillo, Sánchez-Hidalgo, Sánchez-Fidalgo, Aparicio-Soto, Villegas, Alarcón-de-la-Lastra: Dietary extra-virgin olive oil prevents inflammatory response and cartilage matrix degradation in murine collagen-induced arthritis. in European journal of nutrition 2015
SNPs of rs3819024 in IL-17A and rs763780 in IL-17F (show IL17F ELISA Kits) were weakly related to a prognosis of tuberculosis.
this study shows that aberrant NKG2D (show KLRK1 ELISA Kits) expression with IL-17 production of CD4 (show CD4 ELISA Kits)+ T subsets in patients with type 2 diabetes
Luciferase assay using the 5'-UTR (show UTS2R ELISA Kits) of the IL-17 F gene revealed transcriptional regulation. Induced IL-17 F production was further confirmed at the protein level by ELISA. Smad1 (show GARS ELISA Kits)/5/8 inhibitor pretreatment decreased IL-17 F expression levels in the cells.
Study shows increased IL-17A expression in early tendinopathy and proposes IL-17A as an inflammatory regulator in tendon remodeling.
Several studies identified IL-17A as a pro-inflammatory player in atherosclerosis while its expression was associated with increased inflammation and plaque vulnerability in human atherosclerotic lesions. Moreover, IL-17A induced a pro-inflammatory, pro-thrombotic, plaque-destabilizing, and cell-attracting response of the inflammatory milieu of human plaque tissue samples. [review]
asymmetric cell divisions in psoriasis are IL17A-dependent.
Serum IL-23 (show IL23A ELISA Kits) and IL-17 levels were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH (show ASAH1 ELISA Kits)) showing upregulation of IL-23 (show IL23A ELISA Kits)/IL-17 inflammatory axis after aSAH (show ASAH1 ELISA Kits). Serum IL-23 (show IL23A ELISA Kits) and IL-17 showed differential correlations with post hemorrhagic complications and no correlation with clinical outcome.
More prominent IL-17 and IFN-gamma (show IFNG ELISA Kits) production by all lymphocyte subsets in Behcet disease (BD) might be associated with the increased innate responses, early tissue neutrophil infiltrations and late adaptive immunity in BD.
Data showed that IL-17A levels were sustained in respiratory samples from cystic fibrosis (show S100A8 ELISA Kits) patients infected by P. aeruginosa. IL-17 mediated-immunity plays a double-edged found during chronic airways infection: in one hand, it contributes to the control of P. aeruginosa burden, modulating host resistance, while, on the other, it alters host tolerance, propagating exacerbated pulmonary neutrophilia and tissue remodeling.
gamma delta T cells, rather than Th17cells, are the principal producers of IL-17 in acute gouty arthritis patients during the acute gout flares.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 ELISA Kits)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
IL-17A and IL-17F (show IL17F ELISA Kits) exert distinct biological effects during pulmonary infection; the IL-17F (show IL17F ELISA Kits)/IL-17RC (show IL17RC ELISA Kits) signaling axis has the potential to significantly worsen pathogen-associated inflammation of the lower respiratory tract.
TLR2/4-mediated IL-17A inflammatory signaling is involved in vessel degeneration and revascularization, indicating that modulation of the TLR2/4-IL-17A pathway may be a novel therapeutic strategy for degenerative diseases.
The hormone levels are significantly reduced and lymphocytic infiltration in the lacrimal gland in ovariectomized mice, whereas the frequency of Th17 cells in the blood and spleen and IL-17A and IL-23 (show IL23A ELISA Kits) expression in the lacrimal glands are increased, leading to reduced tear production and positive fluorescein staining in the cornea.
the results suggest that IL-17A induces podocyte injury by activating the NLRP3 (show NLRP3 ELISA Kits) inflammasome and IL-1beta (show IL1B ELISA Kits) secretion and contributes to disruption of the kidney's filtration system.
These results suggest that a low concentration of IL-17A is likely to promote autophagic activity via activating RANKL (show TNFSF11 ELISA Kits)-JNK (show MAPK8 ELISA Kits) pathway during osteoclastogenesis.
study shows that IL-17A plays an important role in comorbid depression associated with psoriatic inflammation, where both NFkappaB and p38MAPK (show MAPK14 ELISA Kits) pathways play significant roles via upregulation of inflammatory mediators in the brain
the present study demonstrated that IL-17A crucially regulated the wound healing process and that accelerated neutrophil accumulation caused by IL-17A led to the delayed wound repair.
The results emphasize the importance of IL-17 in experimental autoimmune myasthenia gravis development and that IL-17 independent pathways drive the autoimmune reaction.
In estrogen receptor (show ESR1 ELISA Kits) negative breast cancer cells targeting of IL-17A inhibited PDL1 (show CD274 ELISA Kits) expression in the tumor microenvironment, decreasing the percentage of Treg cells in tumor-infiltrating lymphocytes, and promoting CD4 (show CD4 ELISA Kits)+ and CD8 (show CD8A ELISA Kits)+ T cells to secrete interferon gamma (show IFNG ELISA Kits).
Report provides evidence that IL-17 can promote Lewis lung carcinoma growth through inhibition of myeloid-derived suppressor cells apoptosis, which maybe dependent on ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathway.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 ELISA Kits)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F ELISA Kits) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A ELISA Kits)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 ELISA Kits)(+)CD4 (show CD4 ELISA Kits)(+) and CD3 (show CD3 ELISA Kits)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA ELISA Kits)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17
, interleukin 17A
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)