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The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. Additionally we are shipping IL17A Antibodies (504) and IL17A Proteins (92) and many more products for this protein.
Showing 10 out of 116 products:
Human IL17A ELISA Kit for Sandwich ELISA - ABIN411314
Tan, Liu, Yang, Wang, Qin: An inactivated Pseudomonas aeruginosa medicament inhibits airway allergic inflammation and improves epithelial functions. in The journal of physiological sciences : JPS 2012
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Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN411315
Kotake, Udagawa, Takahashi, Matsuzaki, Itoh, Ishiyama, Saito, Inoue, Kamatani, Gillespie, Martin, Suda: IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. in The Journal of clinical investigation 1999
Show all 11 Pubmed References
Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN625138
Nakai, Yoneda, Hosokawa, Moriue, Presland, Fallon, Kabashima, Kosaka, Kubota: Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies. in The American journal of pathology 2012
Show all 7 Pubmed References
Human IL17A ELISA Kit for Sandwich ELISA - ABIN365737
Deng, Chen, Zheng, Chen, Huang, Yin, Gao, Lin, Huang, Gao, Yu, Liu: Association of BAFF and IL-17A with subphenotypes of primary Sjögren's syndrome. in International journal of rheumatic diseases 2015
Show all 2 Pubmed References
Human IL17A ELISA Kit for Sandwich ELISA - ABIN1446085
Lu, Nossent: Thrombopoietin levels in systemic lupus erythematosus are linked to inflammatory cytokines, but unrelated to thrombocytopenia or thrombosis. in Lupus 2014
Mouse (Murine) IL17A ELISA Kit for Sandwich ELISA - ABIN1446148
Rosillo, Sánchez-Hidalgo, Sánchez-Fidalgo, Aparicio-Soto, Villegas, Alarcón-de-la-Lastra: Dietary extra-virgin olive oil prevents inflammatory response and cartilage matrix degradation in murine collagen-induced arthritis. in European journal of nutrition 2015
these findings suggest that the variants +2199 A/C IL-23R (show IL23R ELISA Kits) and -197 G/A IL-17A could contribute to rheumatoid arthritis development in the studied population
IL-17A rs2275913 polymorphism did not seem to influence RA susceptibility in Tunisian population.
results suggest that IL-17A stimulated keratinocytes activated PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling and inhibited autophagy by simultaneously inhibiting autophagosome formation and enhancing autophagic flux.
In the present review, we have discussed the cellular sources, modes of action and regulation of IL-17 and IL-33 (show IL33 ELISA Kits) in the context of hypersensitive diseases [Review]
Serum IL-17 and IL-23 (show IL23A ELISA Kits) values positively correlated with serum total IgE levels. Serum levels of IL-10 (show IL10 ELISA Kits) were lower in children with atopy and dyslipidemia than patients with dyslipidemia.
the frequencies of IFNgamma and IL-17A(+) cells were increased in the antrum, particularly in patients with H. pylori induced gastric ulcers.
Findings identify interleukin-17A as a potential mediator of neuroanatomical remodeling of the gut (show GUSB ELISA Kits) innervation during inflammatory bowel diseases.
This review discusses recent discoveries related to the pro-inflammatory cytokine IL17A, and its potential role in the pathogenesis of COPD (show ARCN1 ELISA Kits). We propose that an intervention strategy targeting IL-17 signaling offers an exciting opportunity to mitigate inflammatory processes, and prevent the progression of tissue pathologies associated with COPD (show ARCN1 ELISA Kits) [Review]
Study shows that higher baseline levels of Interleukin 17 are selectively associated with greater symptomatic reduction in depressed patients treated with bupropion-SSRI combination.
IL-23 (show IL23A ELISA Kits)/IL-17 axis and biochemical markers in the pathogenesis of Type 2 Diabetes
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (show AOC2 ELISA Kits)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
IL17A promoted osteoblast differentiation and calcification in a partly AKT2dependent manner in MC3T3E1 cells in vitro, possibly reflecting compensation by other signaling pathways. The results of the present study may offer novel perspectives to guide the clinical strategy for the prevention and treatment of periodontitis
Mechanistically, CREB (show CREB1 ELISA Kits), activated by CD3 (show CD3E ELISA Kits)-PKC (show PKC ELISA Kits)- signaling, plays a key role in regulating Th17 cell differentiation, at least in part through directly binding to the Il17-Il17f gene locus.
Data show that interleukin-17 (IL-17) and fungal candidalysin amplify inflammation in a self-reinforcing feed-forward loop.
The data indicate that IL-17A contributes to augmented responses to ozone in db/db (show LEPR ELISA Kits) mice. Furthermore, IL-17A appears to act at least in part by inducing expression of gastrin-releasing peptide receptor (show GRPR ELISA Kits).
miR203 expression may be upregulated by IL17 stimulation, and miR203 is a positive regulator of IL17induced VEGF (show VEGFA ELISA Kits) secretion.
IL-17 contributes to lung obliterative bronchiolitis pathogenesis through regulating macrophages function
we demonstrate that gammadelta T cells and CD4 (show CD4 ELISA Kits)+ T (Th17) cells are the two major producers of IL-17A in the lung at the early and later stages of chlamydial infection, respectively
In mice on a C57BL/6 background, neither IL-23p19 (show IL23A ELISA Kits) nor IL-17A plays a role for immune protection against L. major in the physiological context of natural infections.
IL-17A and IL-17F (show IL17F ELISA Kits) exert distinct biological effects during pulmonary infection; the IL-17F (show IL17F ELISA Kits)/IL-17RC (show IL17RC ELISA Kits) signaling axis has the potential to significantly worsen pathogen-associated inflammation of the lower respiratory tract.
TLR2/4-mediated IL-17A inflammatory signaling is involved in vessel degeneration and revascularization, indicating that modulation of the TLR2/4-IL-17A pathway may be a novel therapeutic strategy for degenerative diseases.
These results support previous gene transcription studies and extend the observation of increased IL-22 (show IL22 ELISA Kits) and IL-17A responses in M. bovis-infected animals to the level of protein production.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (show CD4 ELISA Kits)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (show IL17F ELISA Kits) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (show CD8A ELISA Kits)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (show CD3 ELISA Kits)(+)CD4 (show CD4 ELISA Kits)(+) and CD3 (show CD3 ELISA Kits)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (show IL17RA ELISA Kits)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17
, interleukin 17A
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)