KIAA1524 Proteins (KIAA1524)

Promotes anchorage-independent cell growth and tumor formation (By similarity)..

list all proteins Gene Name GeneID UniProt
Human KIAA1524 KIAA1524 57650 Q8TCG1
Mouse KIAA1524 KIAA1524 224171 Q8BWY9
Rat KIAA1524 KIAA1524 360711  
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Top KIAA1524 Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 60 to 65 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Escherichia coli (E. coli) Human GST tag,His tag 100 μg Log in to see 15 to 18 Days

More Proteins for KIAA1524 Interaction Partners

Human KIAA1524 interaction partners

  1. High expression of CIP2A is associated with cisplatin resistant gastric cancer.

  2. These data reveal that CIP2A is a crucial mediator of FN-induced bladder cancer cell proliferation via enhancing the stabilization of beta-catenin (show CTNNB1 Proteins).

  3. confirmed the high mRNA and protein expression levels of CIP2A in hepatocellular carcinoma (HCC (show FAM126A Proteins)), and found high CIP2A mRNA expression level was associated with unfavorable overall and recurrence-free survival in patients with HCC (show FAM126A Proteins)

  4. High CIP2A expression is associated with gemcitabine resistance in pancreatic cancer.

  5. These results are the first evidence that the inhibition of HDAC1 (show HDAC1 Proteins) by (S)-2 downregulates CIP2A transcription

  6. Membranous CIP2A expression as a potential novel prognostic and predictive indicator for tamoxifen resistance.

  7. Cip2a effectively promotes triple-negative breast cancer (TNBC) cell cycle progression and tumor growth via regulation of PP2A (show PPP2R4 Proteins)/c-myc (show MYC Proteins)/p27Kip1 (show CDKN1B Proteins) signaling, which could serve as a potential therapeutic target for TNBC patients.

  8. poor prognosis of chronic myeloid leukemia (show BCL11A Proteins) patients with high CIP2A levels is due to an antiapoptotic phenotype

  9. Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A (show PPP2R4 Proteins)/B56

  10. CIP2A is upregulated in MM, and CIP2A expression promotes cell proliferation and clonogenic formation ability by regulating the expression of AKT (show AKT1 Proteins) phosphorylation and c-Myc (show MYC Proteins).

Mouse (Murine) KIAA1524 interaction partners

  1. CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A (show AURKA Proteins) during meiotic maturation in mouse oocytes

  2. Knockdown of CIP2A by stable CIP2A siRNA transfection inhibited MDA-MB-231 cell proliferation, invasion, colony growth in vitro, and xenograft growth and metastasis in vivo of breast cancer in mice.

  3. CIP2A as a hitherto unrecognized mediator of T-cell activation.

  4. Downregulation of CIP2A suppresses cell proliferation and growth of nasopharyngeal carcinoma.

  5. CIP2A strongly interacts with NEK2 (show NEK2 Proteins) during G2/M phase, thereby enhancing NEK2 kinase (show NEK2 Proteins) activity to facilitate centrosome separation in a PP1 (show PPP1CC Proteins)- and PP2A (show PPP2R2B Proteins)-independent manner.

  6. Data show that CIP2A expression can be systematically inhibited without severe consequences to normal mouse development and viability may have clinical relevance regarding targeting of oncogenic CIP2A for future cancer therapies.

  7. Loss of CIP2A in Myc (show MYC Proteins)-overexpressing neural progenitor cells significantly reduces the ability of Myc (show MYC Proteins) to increase self-renewal and proliferation.

KIAA1524 Protein Profile

Protein Summary

Promotes anchorage-independent cell growth and tumor formation (By similarity).

Gene names and symbols associated with KIAA1524 Proteins (KIAA1524)

  • cell proliferation regulating inhibitor of protein phosphatase 2A (CIP2A)
  • RIKEN cDNA C330027C09 gene (C330027C09Rik)
  • KIAA1524 (KIAA1524)
  • cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog (cip2a.L)
  • CONSTANS interacting protein 2a (CIP2a)
  • cell proliferation regulating inhibitor of protein phosphatase 2A (cip2a)
  • cell proliferation regulating inhibitor of protein phosphatase 2A (Cip2a)
  • AA408511 protein
  • AU018569 protein
  • Cip2a protein
  • KIAA1524 protein
  • LOC100222895 protein
  • p90 protein
  • RGD1310335 protein

Protein level used designations for KIAA1524 Proteins (KIAA1524)

cancerous inhibitor of PP2A , p90 autoantigen , protein CIP2A , p90 autoantigen homolog , protein CIP2A homolog , KIAA1524 , CONSTANS interacting protein 2a , hypothetical protein LOC100216050

57650 Homo sapiens
224171 Mus musculus
418410 Gallus gallus
494846 Xenopus laevis
538580 Bos taurus
705690 Macaca mulatta
741836 Pan troglodytes
778347 Solanum lycopersicum
100216050 Xenopus (Silurana) tropicalis
100222895 Taeniopygia guttata
360711 Rattus norvegicus
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