anti-Keratin 3/12 (KRT3/12) Antibodies

The protein encoded by KRT3/12 is a member of the keratin gene family.

list all antibodies Gene Name GeneID UniProt
KRT3/12 3850 P12035
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Top anti-Keratin 3/12 Antibodies at

Showing 3 out of 3 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Mouse Un-conjugated WB   100 μg Log in to see 7 to 9 Days
Human Mouse Un-conjugated IHC, WB   200 μg Log in to see 11 to 16 Days
Human Mouse Un-conjugated IHC (fro), WB   200 μg Log in to see 2 to 3 Days

KRT3/12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Cow (Bovine)

Mouse (Murine)

More Antibodies against Keratin 3/12 Interaction Partners

Human Keratin 3/12 (KRT3/12) interaction partners

  1. we show that the two PAX6 (show PAX6 Antibodies) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12 (show KRT12 Antibodies)). PAX6 (show PAX6 Antibodies) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (show KLF4 Antibodies) enhanced this induction. A combination of PAX6 (show PAX6 Antibodies) isoform-b, KLF4 (show KLF4 Antibodies), and OCT4 (show POU5F1 Antibodies) induced KRT12 (show KRT12 Antibodies) expression

  2. Exon sequencing of KRT3 and KRT12 (show KRT12 Antibodies) in six affected and eight unaffected individuals did not detect any mutations or nucleotide sequence variants in Meesmann epithelial corneal dystrophy.

  3. A novel missense mutation (R503P) in KRT3 leads to MCD in 2 unrelated Taiwanese families.

  4. Location of the E498V mutation emphasizes the functional relevance of the highly conserved boundary motifs at the COOH-terminus of the alpha-helical rod domain in keratin 3 (show KRT3 Antibodies) (K3).

Keratin 3/12 (KRT3/12) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene names and symbols associated with anti-Keratin 3/12 (KRT3/12) Antibodies

  • keratin 3 (KRT3) antibody
  • CK3 antibody
  • K3 antibody

Protein level used designations for anti-Keratin 3/12 (KRT3/12) Antibodies

65 kDa cytokeratin , CK-3 , cytokeratin 3 , cytokeratin-3 , keratin, type II cytoskeletal 3 , type-II keratin Kb3

3850 Homo sapiens
Selected quality suppliers for anti-Keratin 3/12 (KRT3/12) Antibodies
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