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The protein encoded by KRT6B is a member of the keratin gene family. Additionally we are shipping Keratin 6B Antibodies (36) and many more products for this protein.
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These results suggested that the upregulation of notch1 (show NOTCH1 Proteins) and KRT6B might be involved in the development, progression and prognosis of human renal cell carcinoma (show MOK Proteins)
Data show that calretinin (show CALB2 Proteins) and CK5 (show KRT5 Proteins)/6 were positive in 100 and 64% of mesotheliomas, and 92 and 31% of reactive effusions, respectively, and desmin (show DES Proteins) was negative in all malignant cases and positive in 85% of reactive effusions.
We found that the KRT16 (show KRT16 Proteins) mutation carriers developed plantar keratoderma at a similar age to KRT6a (show KRT6A Proteins) carriers wheras KRT6B and KRT17 (show KRT17 Proteins) carriers were significantly more likely to report later onset.
Studies show that the intrinsic molecular signature of five markers, ER, PR, HER-2 (show ERBB2 Proteins), CK 5 (show KRT5 Proteins)/6, and EGFR (show EGFR Proteins), demonstrated specificity of 100% and sensitivity of 75%, compared with classification by gene expression profiling.
Although K6a (show KRT6A Proteins) was not essential for mammary gland development, loss of both K6a (show KRT6A Proteins) and K6b resulted in an increase in PR-positive mammary epithelial cells and decreased proliferation after exposure to steroid hormones
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified\; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
cytokeratin 6B , cytokeratin-6B , keratin, epidermal, type II, K6B , keratin, type II cytoskeletal 6B , keratin-6B , keratin-like 1 (a type II keratin sequence) , type-II keratin Kb10 , keratin 6C , keratin 6A , keratin 6B , CK-6B , K6B , keratin complex 2, basic, gene 6b , keratin-6-beta , mK6-beta , cytokeratin type II, component IV , keratin K6-gamma , keratin, type II cytoskeletal 59 kDa, component IV