Kin of IRRE Like 3 (Drosophila) (KIRREL3) ELISA Kits

The protein encoded by KIRREL3 is a member of the nephrin-like protein family. Additionally we are shipping KIRREL3 Antibodies (37) and KIRREL3 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KIRREL3 84623 Q8IZU9
KIRREL3 67703 Q8BR86
Anti-Rat KIRREL3 KIRREL3 315546  
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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.021 ng/mL n/a   96 Tests 11 to 16 Days
  96 Tests 2 to 3 Days
  96 Tests 21 to 31 Days

More ELISA Kits for KIRREL3 Interaction Partners

Human Kin of IRRE Like 3 (Drosophila) (KIRREL3) interaction partners

  1. KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder.

  2. Results presented demonstrate for the first time that there are at least 3 splice variants of Kirrel3 expressed in adult human skeletal muscle, two of which have never previously been identified in human muscle.

  3. Alterations in KIRREL3 in patients with mild to severe intellectual disability are reported.

Mouse (Murine) Kin of IRRE Like 3 (Drosophila) (KIRREL3) interaction partners

  1. The results of this study demonstrate that Kirrel2 and Kirrel3 are essential for the formation of glomeruli and suggest they contribute to synaptogenesis in the accessory olfactory bulb.

  2. Findings provide evidence that Kirrel3(-/-) mice exhibit autistic-like behaviors, including social and communicative deficits, repetitive behaviors, and sensory abnormalities, as well as hyperactivity.

  3. This study demonstrated that selective loss of mossy fiber filopodial synapses with GABA neurons likely underlies the hippocampal activity imbalance observed in Kirrel3 knockout mice and may impact neural function in patients with Kirrel3-dependent neurodevelopmental disorders.

  4. mouse Kirrel3 is a myobast adhesion molecule which promotes the morphological change of rounded MPC to a spindle shaped myocyte that migrates in a directed fashion and participates in the tight interactions between myocytes prior to their fusion

  5. Kirrel3 is required for formation of hippocampal mossy fiber filopodia; the structures that give rise to dentate granule-GABA synapses and that regulate feed-forward inhibition of CA3 neurons.

  6. Kirrel3 has a role in coalescence of vomeronasal sensory neuron axons into glomeruli and in male-male aggression in a resident-intruder assay

  7. Here we demonstrate that Neph1, Neph2, and Neph3 are expressed differentially in various tissues during ontogenesis in mouse and chicken.

  8. Results suggest Neph2 is involved in the nucleogenesis of the pontine nucleus through the control of neuronal migration inside the nucleus.

  9. involved in the hematopoietic supportive capacity of OP9 mouse stromal cells

  10. The spatiotemporal expression pattern of mKirre mRNA suggests important roles of mKirre in later developmental processes, especially the synapse formation.

  11. In the adult brain, Neph2 is seen in the olfactory nerve layer and the glomerular layer of the olfactory bulb, in the hippocampus, and in cerebellar Purkinje cells. At the ultrastructural level, Neph2 is seen in dendritic shafts of pyramidal neurons.

  12. These results suggest that mKirre may be involved in the establishment of the pathway from sensory organs to the brain.

  13. Results suggest that Kirrel3 plays a role in the axonal pathfinding, cell recognition, and synapse formation of DRG neurons on target cells, including the targeting of proprioceptive neurons on muscle spindles through the interaction with nephrin.

KIRREL3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KIRREL3

  • kirre like nephrin family adhesion molecule 3 (KIRREL3) antibody
  • kin of IRRE like 3 (Drosophila) (Kirrel3) antibody
  • kin of IRRE like 3 (Drosophila) (KIRREL3) antibody
  • kirre like nephrin family adhesion molecule 3 (Kirrel3) antibody
  • 1500010O20Rik antibody
  • 2900036G11Rik antibody
  • KIRRE antibody
  • mKIAA1867 antibody
  • MRD4 antibody
  • NEPH2 antibody
  • PRO4502 antibody
  • SST4 antibody

Protein level used designations for KIRREL3

kin of IRRE like 3 (Drosophila) , kin of IRRE-like protein 3 , kin of irregular chiasm-like protein 3 , nephrin-like 2 , nephrin-like protein 2 , X kin of IRRE like 3 , membrane protein mKirre

489289 Canis lupus familiaris
84623 Homo sapiens
67703 Mus musculus
419719 Gallus gallus
315546 Rattus norvegicus
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