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LSM1 encodes a member of the LSm family of RNA-binding proteins.
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Cow (Bovine) Polyclonal LSM1 Primary Antibody for IHC, WB - ABIN2779063
Jhanji, Lee, Watson, Hinds, Pearse: Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications. in Intensive care medicine 2009
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These results provide evidence that LSm1 binding to the DENV RNA 3' UTR (show UTS2R Antibodies) positively regulates DENV RNA replication.
The results of this study provided further support for previous genetic findings reporting the association of an intronic SNP (rs16887244) in LSM1 and schizophrenia in a Chinese sample
Lsm1 is deeply involved in prostate cancer progression through its down-regulation, independent of any gene mutation.
LSm1-7 proteins colocalize with DCP1 (show ACE Antibodies),DCP2 (show DCP2 Antibodies) and Xrn1 (show XRN1 Antibodies) in cytoplasmic foci
LSM1 is a breast cancer oncogene (show RAB1A Antibodies) from the 8p11-12 amplicon.
Results suggest that LSm-1/CaSm functions as an oncogene (show RAB1A Antibodies) in the promotion of cellular transformation and cancer progression.
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
LSM1 homolog, U6 small nuclear RNA associated
, U6 snRNA-associated Sm-like protein LSm1
, cancer-associated Sm-like protein
, small nuclear ribonuclear CaSm